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Ameloblastic Carcinoma Derived From Odontogenic Cyst

MedGen UID:
231053
•Concept ID:
C1332242
•
Neoplastic Process
Synonym: Ameloblastic Carcinoma Ex Odontogenic Cyst

Definition

A rare, aggressive malignant tumor that originates from an odontogenic cyst in the maxillomandibular region. It combines the histologic features of an ameloblastoma and carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAmeloblastic Carcinoma Derived From Odontogenic Cyst

Recent clinical studies

Etiology

BDNF/TrkB/Akt Signaling Pathway Epithelial Odontogenic Tumors and Keratocyst: An Immunohistochemical Study Comparative With Dental Germs.
Dornelles FML, Wagner VP, Fonseca FP, Ariotti C, Carrard VC, Vargas PA, Sánchez-Romero C, Beovide V, Bologna-Molina R, Martins MD
Appl Immunohistochem Mol Morphol 2021 May-Jun 01;29(5):366-373. doi: 10.1097/PAI.0000000000000874. PMID: 32941187
Malignant odontogenic tumors: a 22-year experience.
Goldenberg D, Sciubba J, Koch W, Tufano RP
Laryngoscope 2004 Oct;114(10):1770-4. doi: 10.1097/00005537-200410000-00018. PMID: 15454770

Diagnosis

Malignant odontogenic tumors: a 22-year experience.
Goldenberg D, Sciubba J, Koch W, Tufano RP
Laryngoscope 2004 Oct;114(10):1770-4. doi: 10.1097/00005537-200410000-00018. PMID: 15454770

Therapy

BDNF/TrkB/Akt Signaling Pathway Epithelial Odontogenic Tumors and Keratocyst: An Immunohistochemical Study Comparative With Dental Germs.
Dornelles FML, Wagner VP, Fonseca FP, Ariotti C, Carrard VC, Vargas PA, Sánchez-Romero C, Beovide V, Bologna-Molina R, Martins MD
Appl Immunohistochem Mol Morphol 2021 May-Jun 01;29(5):366-373. doi: 10.1097/PAI.0000000000000874. PMID: 32941187

Clinical prediction guides

BDNF/TrkB/Akt Signaling Pathway Epithelial Odontogenic Tumors and Keratocyst: An Immunohistochemical Study Comparative With Dental Germs.
Dornelles FML, Wagner VP, Fonseca FP, Ariotti C, Carrard VC, Vargas PA, Sánchez-Romero C, Beovide V, Bologna-Molina R, Martins MD
Appl Immunohistochem Mol Morphol 2021 May-Jun 01;29(5):366-373. doi: 10.1097/PAI.0000000000000874. PMID: 32941187
Teratocarcinoma-derived growth factor-1 (Cripto-1) is overexpressed in epithelial odontogenic lesions displaying more aggressive behaviour.
da Silva LP, Severo MLB, da Silva LAB, Galvão HC, de Souza LB, da Costa Miguel MC
Oral Maxillofac Surg 2020 Dec;24(4):455-460. Epub 2020 Jul 5 doi: 10.1007/s10006-020-00877-0. PMID: 32623516

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