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Hemispheric Anaplastic Astrocytoma

MedGen UID:
231069
•Concept ID:
C1332282
•
Neoplastic Process
Synonyms: Anaplastic Astrocytoma of Cerebral Hemisphere; Anaplastic Astrocytoma of the Cerebral Hemisphere; Anaplastic Astrocytoma, Hemispheric; Anaplastic Hemispheric Astrocytoma; Cerebral Hemisphere Anaplastic Astrocytoma; Grade 3 Astrocytic Neoplasm of Cerebral Hemisphere; Grade 3 Astrocytic Neoplasm of the Cerebral Hemisphere; Grade 3 Astrocytic Tumor of Cerebral Hemisphere; Grade 3 Astrocytic Tumor of the Cerebral Hemisphere; Grade 3 Astrocytoma of Cerebral Hemisphere; Grade 3 Astrocytoma of the Cerebral Hemisphere; Grade 3 Cerebral Hemisphere Astrocytic Neoplasm; Grade 3 Cerebral Hemisphere Astrocytoma; Grade 3 Hemispheric Astrocytic Neoplasm; Grade 3 Hemispheric Astrocytic Tumor; Grade 3 Hemispheric Astrocytoma; Grade III Astrocytic Neoplasm of Cerebral Hemisphere; Grade III Astrocytic Neoplasm of the Cerebral Hemisphere; Grade III Astrocytic Tumor of Cerebral Hemisphere; Grade III Astrocytic Tumor of the Cerebral Hemisphere; Grade III Astrocytoma of Cerebral Hemisphere; Grade III Cerebral Hemisphere Astrocytic Neoplasm; Grade III Cerebral Hemisphere Astrocytic Tumor; Grade III Cerebral Hemisphere Astrocytoma; Grade III Hemispheric Astrocytic Neoplasm; Grade III Hemispheric Astrocytic Tumor; Grade III Hemispheric Astrocytoma; Undifferentiated Astrocytoma of Cerebral Hemisphere; Undifferentiated Astrocytoma of the Cerebral Hemisphere

Definition

An anaplastic astrocytoma that arises from the cerebral hemispheres. [from NCI]

Professional guidelines

PubMed

Local treatment for relapsing glioblastoma: A decision-making tree for choosing between reirradiation and second surgery.
Scoccianti S, Perna M, Olmetto E, Delli Paoli C, Terziani F, Ciccone LP, Detti B, Greto D, Simontacchi G, Grassi R, Scoccimarro E, Bonomo P, Mangoni M, Desideri I, Di Cataldo V, Vernaleone M, Casati M, Pallotta S, Livi L
Crit Rev Oncol Hematol 2021 Jan;157:103184. Epub 2020 Nov 28 doi: 10.1016/j.critrevonc.2020.103184. PMID: 33307416
Management of Glioblastoma Multiforme by Phytochemicals: Applications of Nanoparticle-Based Targeted Drug Delivery System.
Mumtaz SM, Bhardwaj G, Goswami S, Tonk RK, Goyal RK, Abu-Izneid T, Pottoo FH
Curr Drug Targets 2021;22(4):429-442. doi: 10.2174/1389450121666200727115454. PMID: 32718288
Conventional chemotherapy and perspectives for molecular-based oncological treatment in pediatric hemispheric low-grade gliomas.
Fernández MB, Alonso VP
Childs Nerv Syst 2016 Oct;32(10):1939-45. Epub 2016 Sep 20 doi: 10.1007/s00381-016-3132-0. PMID: 27659836

Recent clinical studies

Etiology

Long-term seizure outcomes in adult patients undergoing primary resection of malignant brain astrocytomas. Clinical article.
Chaichana KL, Parker SL, Olivi A, Quiñones-Hinojosa A
J Neurosurg 2009 Aug;111(2):282-92. doi: 10.3171/2009.2.JNS081132. PMID: 19344222
Volumetric extent of resection and residual contrast enhancement on initial surgery as predictors of outcome in adult patients with hemispheric anaplastic astrocytoma.
Keles GE, Chang EF, Lamborn KR, Tihan T, Chang CJ, Chang SM, Berger MS
J Neurosurg 2006 Jul;105(1):34-40. doi: 10.3171/jns.2006.105.1.34. PMID: 16871879

Diagnosis

Volumetric extent of resection and residual contrast enhancement on initial surgery as predictors of outcome in adult patients with hemispheric anaplastic astrocytoma.
Keles GE, Chang EF, Lamborn KR, Tihan T, Chang CJ, Chang SM, Berger MS
J Neurosurg 2006 Jul;105(1):34-40. doi: 10.3171/jns.2006.105.1.34. PMID: 16871879
Cytodiagnosis of anaplastic astrocytoma with metastasis to the cerebrospinal fluid in a neonate--a case report.
Goel S, Kapila K, Sarkar C, Verma K
Neurol India 2003 Jun;51(2):276-7. PMID: 14571028

Therapy

Immunotherapy with stimulated autologous lymphocytes in a case of a juvenile anaplastic glioma.
Thomas C, Schober R, Lenard HG, Lumenta CB, Jacques DB, Wechsler W
Neuropediatrics 1992 Jun;23(3):123-5. doi: 10.1055/s-2008-1071326. PMID: 1641079

Prognosis

Volumetric extent of resection and residual contrast enhancement on initial surgery as predictors of outcome in adult patients with hemispheric anaplastic astrocytoma.
Keles GE, Chang EF, Lamborn KR, Tihan T, Chang CJ, Chang SM, Berger MS
J Neurosurg 2006 Jul;105(1):34-40. doi: 10.3171/jns.2006.105.1.34. PMID: 16871879

Clinical prediction guides

Long-term seizure outcomes in adult patients undergoing primary resection of malignant brain astrocytomas. Clinical article.
Chaichana KL, Parker SL, Olivi A, Quiñones-Hinojosa A
J Neurosurg 2009 Aug;111(2):282-92. doi: 10.3171/2009.2.JNS081132. PMID: 19344222
Volumetric extent of resection and residual contrast enhancement on initial surgery as predictors of outcome in adult patients with hemispheric anaplastic astrocytoma.
Keles GE, Chang EF, Lamborn KR, Tihan T, Chang CJ, Chang SM, Berger MS
J Neurosurg 2006 Jul;105(1):34-40. doi: 10.3171/jns.2006.105.1.34. PMID: 16871879

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