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Childhood Benign Brain Neoplasm

MedGen UID:: 231425
•Concept ID:: C1332482
•: Neoplastic Process

Synonyms:

Benign Childhood Brain Neoplasm; Benign Childhood Brain Tumor; Benign Childhood Neoplasm of Brain; Benign Childhood Neoplasm of the Brain; Benign Childhood Tumor of Brain; Benign Childhood Tumor of the Brain; Benign Pediatric Brain Neoplasm; Benign Pediatric Brain Tumor; Benign Pediatric Neoplasm of Brain; Benign Pediatric Neoplasm of the Brain; Benign Pediatric Tumor of Brain; Benign Pediatric Tumor of the Brain

Definition

A childhood neoplasm that arises from the brain and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVChildhood Benign Brain Neoplasm

Disorder of nervous system
- Disorder of the central nervous system
  - Neoplasm of the central nervous system
    - Intracranial Neoplasm
      - Benign Intracranial Neoplasm
        Benign neoplasm of brain
        Childhood Benign Brain Neoplasm
        Childhood Benign Supratentorial Neoplasm
        Childhood Benign Cerebral Neoplasm
        Childhood Choroid Plexus Papilloma

Professional guidelines

PubMed

Advances in the Diagnosis and Treatment of Pediatric Arterial Ischemic Stroke.

Sun LR, Lynch JK
Neurotherapeutics 2023 Apr;20(3):633-654. Epub 2023 Apr 18 doi: 10.1007/s13311-023-01373-5. PMID: 37072548 Free PMC Article

Molecular stratifications, biomarker candidates and new therapeutic options in current medulloblastoma treatment approaches.

Menyhárt O, Győrffy B
Cancer Metastasis Rev 2020 Mar;39(1):211-233. doi: 10.1007/s10555-020-09854-1. PMID: 31970590 Free PMC Article

Childhood brain tumors: current management, biological insights, and future directions.

Pollack IF, Agnihotri S, Broniscer A
J Neurosurg Pediatr 2019 Mar 1;23(3):261-273. doi: 10.3171/2018.10.PEDS18377. PMID: 30835699 Free PMC Article

See all (456)

Recent clinical studies

Etiology

Epidemiology of Brain and Other CNS Tumors.

Ostrom QT, Francis SS, Barnholtz-Sloan JS
Curr Neurol Neurosci Rep 2021 Nov 24;21(12):68. doi: 10.1007/s11910-021-01152-9. PMID: 34817716 Free PMC Article

Risk factors for childhood and adult primary brain tumors.

Ostrom QT, Adel Fahmideh M, Cote DJ, Muskens IS, Schraw JM, Scheurer ME, Bondy ML
Neuro Oncol 2019 Nov 4;21(11):1357-1375. doi: 10.1093/neuonc/noz123. PMID: 31301133 Free PMC Article

Childhood brain tumors: current management, biological insights, and future directions.

Pollack IF, Agnihotri S, Broniscer A
J Neurosurg Pediatr 2019 Mar 1;23(3):261-273. doi: 10.3171/2018.10.PEDS18377. PMID: 30835699 Free PMC Article

Medulloblastoma.

Millard NE, De Braganca KC
J Child Neurol 2016 Oct;31(12):1341-53. Epub 2015 Sep 2 doi: 10.1177/0883073815600866. PMID: 26336203 Free PMC Article

Pediatric brain tumors.

Wells EM, Packer RJ
Continuum (Minneap Minn) 2015 Apr;21(2 Neuro-oncology):373-96. doi: 10.1212/01.CON.0000464176.96311.d1. PMID: 25837902

See all (2911)

Diagnosis

Pediatric Neuro-Oncology.

Malbari F
Neurol Clin 2021 Aug;39(3):829-845. Epub 2021 Jun 10 doi: 10.1016/j.ncl.2021.04.005. PMID: 34215389

Risk factors for childhood and adult primary brain tumors.

Ostrom QT, Adel Fahmideh M, Cote DJ, Muskens IS, Schraw JM, Scheurer ME, Bondy ML
Neuro Oncol 2019 Nov 4;21(11):1357-1375. doi: 10.1093/neuonc/noz123. PMID: 31301133 Free PMC Article

Pediatric Brain Tumors.

Udaka YT, Packer RJ
Neurol Clin 2018 Aug;36(3):533-556. doi: 10.1016/j.ncl.2018.04.009. PMID: 30072070

Medulloblastoma.

Millard NE, De Braganca KC
J Child Neurol 2016 Oct;31(12):1341-53. Epub 2015 Sep 2 doi: 10.1177/0883073815600866. PMID: 26336203 Free PMC Article

Pediatric brain tumors.

Wells EM, Packer RJ
Continuum (Minneap Minn) 2015 Apr;21(2 Neuro-oncology):373-96. doi: 10.1212/01.CON.0000464176.96311.d1. PMID: 25837902

See all (2875)

Therapy

Molecular-Targeted Therapy for Childhood Brain Tumors: A Moving Target.

Packer RJ, Kilburn L
J Child Neurol 2020 Oct;35(12):791-798. Epub 2020 Jun 18 doi: 10.1177/0883073820931635. PMID: 32552173

Neurocognitive Outcomes in Children with Brain Tumors.

Kline CN, Mueller S
Semin Neurol 2020 Jun;40(3):315-321. Epub 2020 May 11 doi: 10.1055/s-0040-1708867. PMID: 32392601

Molecular stratifications, biomarker candidates and new therapeutic options in current medulloblastoma treatment approaches.

Menyhárt O, Győrffy B
Cancer Metastasis Rev 2020 Mar;39(1):211-233. doi: 10.1007/s10555-020-09854-1. PMID: 31970590 Free PMC Article

Childhood brain tumors: current management, biological insights, and future directions.

Pollack IF, Agnihotri S, Broniscer A
J Neurosurg Pediatr 2019 Mar 1;23(3):261-273. doi: 10.3171/2018.10.PEDS18377. PMID: 30835699 Free PMC Article

Craniopharyngioma.

Müller HL
Handb Clin Neurol 2014;124:235-53. doi: 10.1016/B978-0-444-59602-4.00016-2. PMID: 25248591

See all (1602)

Prognosis

Epidemiology of Brain and Other CNS Tumors.

Ostrom QT, Francis SS, Barnholtz-Sloan JS
Curr Neurol Neurosci Rep 2021 Nov 24;21(12):68. doi: 10.1007/s11910-021-01152-9. PMID: 34817716 Free PMC Article

Pediatric Neuro-Oncology.

Malbari F
Neurol Clin 2021 Aug;39(3):829-845. Epub 2021 Jun 10 doi: 10.1016/j.ncl.2021.04.005. PMID: 34215389

Childhood brain tumors: current management, biological insights, and future directions.

Pollack IF, Agnihotri S, Broniscer A
J Neurosurg Pediatr 2019 Mar 1;23(3):261-273. doi: 10.3171/2018.10.PEDS18377. PMID: 30835699 Free PMC Article

Medulloblastoma.

Millard NE, De Braganca KC
J Child Neurol 2016 Oct;31(12):1341-53. Epub 2015 Sep 2 doi: 10.1177/0883073815600866. PMID: 26336203 Free PMC Article

Pediatric brain tumors.

Wells EM, Packer RJ
Continuum (Minneap Minn) 2015 Apr;21(2 Neuro-oncology):373-96. doi: 10.1212/01.CON.0000464176.96311.d1. PMID: 25837902

See all (2192)

Clinical prediction guides

Posterior fossa tumors in children: current insights.

Formentin C, Joaquim AF, Ghizoni E
Eur J Pediatr 2023 Nov;182(11):4833-4850. Epub 2023 Sep 8 doi: 10.1007/s00431-023-05189-5. PMID: 37679511

Updates in the classification of ependymal neoplasms: The 2021 WHO Classification and beyond.

Kresbach C, Neyazi S, Schüller U
Brain Pathol 2022 Jul;32(4):e13068. Epub 2022 Mar 21 doi: 10.1111/bpa.13068. PMID: 35307892 Free PMC Article

Immune profiling of pediatric solid tumors.

Terry RL, Meyran D, Ziegler DS, Haber M, Ekert PG, Trapani JA, Neeson PJ
J Clin Invest 2020 Jul 1;130(7):3391-3402. doi: 10.1172/JCI137181. PMID: 32538896 Free PMC Article

Neurocognitive Outcomes in Children with Brain Tumors.

Kline CN, Mueller S
Semin Neurol 2020 Jun;40(3):315-321. Epub 2020 May 11 doi: 10.1055/s-0040-1708867. PMID: 32392601

Molecular genetics of gliomas.

Appin CL, Brat DJ
Cancer J 2014 Jan-Feb;20(1):66-72. doi: 10.1097/PPO.0000000000000020. PMID: 24445767

See all (1372)

Recent systematic reviews

Risk factors for childhood brain tumours: A systematic review and meta-analysis of observational studies from 1976 to 2022.

Onyije FM, Dolatkhah R, Olsson A, Bouaoun L, Deltour I, Erdmann F, Bonaventure A, Scheurer ME, Clavel J, Schüz J
Cancer Epidemiol 2024 Feb;88:102510. Epub 2023 Dec 5 doi: 10.1016/j.canep.2023.102510. PMID: 38056243 Free PMC Article

Communication and swallowing outcomes of children diagnosed with childhood brain tumor or leukemia: A systematic review.

Hodges R, Campbell L, Chami S, Knijnik SR, Docking K
Pediatr Blood Cancer 2021 Feb;68(2):e28809. Epub 2020 Nov 21 doi: 10.1002/pbc.28809. PMID: 33219751

Overweight, obesity and adiposity in survivors of childhood brain tumours: a systematic review and meta-analysis.

Wang KW, Fleming A, Johnston DL, Zelcer SM, Rassekh SR, Ladhani S, Socha A, Shinuda J, Jaber S, Burrow S, Singh SK, Banfield L, de Souza RJ, Thabane L, Samaan MC
Clin Obes 2018 Feb;8(1):55-67. Epub 2017 Oct 11 doi: 10.1111/cob.12224. PMID: 29024558

Childhood Brain Tumors: a Systematic Review of the Structural Neuroimaging Literature.

Ailion AS, Hortman K, King TZ
Neuropsychol Rev 2017 Sep;27(3):220-244. Epub 2017 Jun 23 doi: 10.1007/s11065-017-9352-6. PMID: 28646252

Neuropsychiatric presentations and outcomes in children and adolescents with primary brain tumours: Systematic review.

Zyrianova Y, Alexander L, Faruqui R
Brain Inj 2016;30(1):1-9. Epub 2015 Nov 5 doi: 10.3109/02699052.2015.1075590. PMID: 26536821

See all (75)

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Childhood Benign Brain Neoplasm

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

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