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Bone Glomus Tumor

MedGen UID:
231952
•Concept ID:
C1332577
•
Neoplastic Process
Synonyms: Bone Glomus Neoplasm; Glomus Neoplasm of Bone; Glomus Neoplasm of the Bone; Glomus Tumor of Bone; Glomus Tumor of the Bone; Osseous Glomus Neoplasm; Osseous Glomus Tumor

Definition

A benign or malignant glomus tumor arising from the bone. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBone Glomus Tumor

Professional guidelines

PubMed

Management of the Hand Tumors.
Datta NK, Das KP, Aish PK, Datta M, Banik SK, Sen SK, Chowdhury RM
Mymensingh Med J 2023 Jan;32(1):135-143. PMID: 36594313
Clinical evaluation and management of benign soft tissue tumors of the extremities.
Erwteman AS, Balach T
Cancer Treat Res 2014;162:171-202. doi: 10.1007/978-3-319-07323-1_9. PMID: 25070236
Imaging and management of head and neck paragangliomas.
van den Berg R
Eur Radiol 2005 Jul;15(7):1310-8. Epub 2005 Apr 5 doi: 10.1007/s00330-005-2743-8. PMID: 15809825

Recent clinical studies

Etiology

Management of the Hand Tumors.
Datta NK, Das KP, Aish PK, Datta M, Banik SK, Sen SK, Chowdhury RM
Mymensingh Med J 2023 Jan;32(1):135-143. PMID: 36594313
High resolution MRI of nail tumors and tumor-like conditions.
Mundada P, Becker M, Lenoir V, Stefanelli S, Rougemont AL, Beaulieu JY, Boudabbous S
Eur J Radiol 2019 Mar;112:93-105. Epub 2019 Jan 6 doi: 10.1016/j.ejrad.2019.01.004. PMID: 30777226
The glomus tumor resorbed bone and teeth in the mandible: a case report.
Kurohara K, Michi Y, Yukimori A, Yamaguchi S
Head Face Med 2018 Sep 25;14(1):18. doi: 10.1186/s13005-018-0175-3. PMID: 30253798Free PMC Article
A Distinct Malignant Epithelioid Neoplasm With GLI1 Gene Rearrangements, Frequent S100 Protein Expression, and Metastatic Potential: Expanding the Spectrum of Pathologic Entities With ACTB/MALAT1/PTCH1-GLI1 Fusions.
Antonescu CR, Agaram NP, Sung YS, Zhang L, Swanson D, Dickson BC
Am J Surg Pathol 2018 Apr;42(4):553-560. doi: 10.1097/PAS.0000000000001010. PMID: 29309307Free PMC Article
Malignant glomus tumors.
Manolidis S, Shohet JA, Jackson CG, Glasscock ME 3rd
Laryngoscope 1999 Jan;109(1):30-4. doi: 10.1097/00005537-199901000-00007. PMID: 9917036

Diagnosis

Jugular Foramen Paragangliomas.
Ceccato GHW, Borba LAB
Adv Tech Stand Neurosurg 2024;49:201-229. doi: 10.1007/978-3-031-42398-7_10. PMID: 38700686
Metastatic paraganglioma.
Harmsworth D, Mallia A, DeGaetano J, Cassar PJ
BMJ Case Rep 2023 Jan 17;16(1) doi: 10.1136/bcr-2022-252449. PMID: 36653043Free PMC Article
A Distinct Malignant Epithelioid Neoplasm With GLI1 Gene Rearrangements, Frequent S100 Protein Expression, and Metastatic Potential: Expanding the Spectrum of Pathologic Entities With ACTB/MALAT1/PTCH1-GLI1 Fusions.
Antonescu CR, Agaram NP, Sung YS, Zhang L, Swanson D, Dickson BC
Am J Surg Pathol 2018 Apr;42(4):553-560. doi: 10.1097/PAS.0000000000001010. PMID: 29309307Free PMC Article
Benign bone tumors.
Motamedi K, Seeger LL
Radiol Clin North Am 2011 Nov;49(6):1115-34, v. doi: 10.1016/j.rcl.2011.07.002. PMID: 22024291
Jugulotympanic paragangliomas.
Weber PC, Patel S
Otolaryngol Clin North Am 2001 Dec;34(6):1231-40, x. doi: 10.1016/s0030-6665(05)70376-5. PMID: 11728943

Therapy

Role of Stereotactic Radiosurgery in Skull Base Paragangliomas - A Narrative Review.
Garg K, Singh M
Neurol India 2023 Mar-Apr;71(Supplement):S153-S160. doi: 10.4103/0028-3886.373640. PMID: 37026347
DIAGNOSIS OF ENDOCRINE DISEASE: Expanding the cause of hypopituitarism.
Pekic S, Popovic V
Eur J Endocrinol 2017 Jun;176(6):R269-R282. Epub 2017 Mar 3 doi: 10.1530/EJE-16-1065. PMID: 28258131
Middle ear and mastoid glomus tumors (glomus tympanicum): an algorithm for the surgical management.
Sanna M, Fois P, Pasanisi E, Russo A, Bacciu A
Auris Nasus Larynx 2010 Dec;37(6):661-8. Epub 2010 Apr 18 doi: 10.1016/j.anl.2010.03.006. PMID: 20400250
Vascular lesions of the skull base: endovascular prospective for the otolaryngologist.
Robinson DH
Otolaryngol Clin North Am 2005 Aug;38(4):737-71. doi: 10.1016/j.otc.2005.03.008. PMID: 16005729
Glomus jugulare tumors with intracranial extension.
Jackson CG, Kaylie DM, Coppit G, Gardner EK
Neurosurg Focus 2004 Aug 15;17(2):E7. doi: 10.3171/foc.2004.17.2.7. PMID: 15329022

Prognosis

Management of the Hand Tumors.
Datta NK, Das KP, Aish PK, Datta M, Banik SK, Sen SK, Chowdhury RM
Mymensingh Med J 2023 Jan;32(1):135-143. PMID: 36594313
Gamma Knife radiosurgery for glomus tumors: Long-term results in a series of 30 patients.
Spina A, Boari N, Gagliardi F, Bailo M, Del Vecchio A, Bolognesi A, Mortini P
Head Neck 2018 Dec;40(12):2677-2684. Epub 2018 Nov 20 doi: 10.1002/hed.25517. PMID: 30456888
The glomus tumor resorbed bone and teeth in the mandible: a case report.
Kurohara K, Michi Y, Yukimori A, Yamaguchi S
Head Face Med 2018 Sep 25;14(1):18. doi: 10.1186/s13005-018-0175-3. PMID: 30253798Free PMC Article
A Distinct Malignant Epithelioid Neoplasm With GLI1 Gene Rearrangements, Frequent S100 Protein Expression, and Metastatic Potential: Expanding the Spectrum of Pathologic Entities With ACTB/MALAT1/PTCH1-GLI1 Fusions.
Antonescu CR, Agaram NP, Sung YS, Zhang L, Swanson D, Dickson BC
Am J Surg Pathol 2018 Apr;42(4):553-560. doi: 10.1097/PAS.0000000000001010. PMID: 29309307Free PMC Article
Malignant glomus tumors.
Manolidis S, Shohet JA, Jackson CG, Glasscock ME 3rd
Laryngoscope 1999 Jan;109(1):30-4. doi: 10.1097/00005537-199901000-00007. PMID: 9917036

Clinical prediction guides

The glomus tumor resorbed bone and teeth in the mandible: a case report.
Kurohara K, Michi Y, Yukimori A, Yamaguchi S
Head Face Med 2018 Sep 25;14(1):18. doi: 10.1186/s13005-018-0175-3. PMID: 30253798Free PMC Article
Nonparaganglioma jugular foramen tumors.
Thomas AJ, Wiggins RH 3rd, Gurgel RK
Otolaryngol Clin North Am 2015 Apr;48(2):343-59. Epub 2015 Feb 4 doi: 10.1016/j.otc.2014.12.008. PMID: 25659512
Paragangliomas of the temporal bone.
Stewart KL
Am J Otolaryngol 1993 Jul-Aug;14(4):219-26. doi: 10.1016/0196-0709(93)90064-e. PMID: 8214313
Common tumors.
Diao E, Moy OJ
Orthop Clin North Am 1992 Jan;23(1):187-96. PMID: 1309601
Adult infratentorial tumors.
Bilaniuk LT
Semin Roentgenol 1990 Apr;25(2):155-73. doi: 10.1016/0037-198x(90)90047-8. PMID: 2349487

Recent systematic reviews

Tumor progression in tympanojugular paragangliomas: the role of radiotherapy and wait and scan.
Fancello G, Fancello V, Ehsani D, Porpiglia V, Piras G, Caruso A, Sanna M
Eur Arch Otorhinolaryngol 2024 Jun;281(6):2779-2789. Epub 2024 Jan 6 doi: 10.1007/s00405-023-08413-y. PMID: 38184495
Anaplastic Hemangiopericytoma of the Jugular Foramen: Case Report and Systematic Review.
Li D, Westfall E, Aasen M, Borys E, Leonetti JP, Anderson DE
World Neurosurg 2021 Sep;153:11-20. Epub 2021 Jun 26 doi: 10.1016/j.wneu.2021.06.094. PMID: 34182175
Primary Paraganglioma of the Facial Canal: An Evidence-Based Approach.
Yuhan BT, Trang A, Hutz MJ, Leonetti JP
Otolaryngol Head Neck Surg 2020 Apr;162(4):458-468. Epub 2020 Feb 25 doi: 10.1177/0194599820907303. PMID: 32093508

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