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Endobronchial Hamartoma

MedGen UID:
232454
•Concept ID:
C1333385
•
Neoplastic Process

Definition

A benign neoplasm that arises endobronchially. It is characterized by the presence of mesenchymal tissues admixed with entrapped respiratory epithelium. It presents with signs and symptoms of bronchial obstruction. Bronchoplastic resection is usually curative. Recurrence is very rare. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEndobronchial Hamartoma

Professional guidelines

PubMed

Can we prevent recurrences in the endoscopic treatment of endobronchial hamartomas?
Aktaş Z, Yılmaz A, Öztürk A, Karataş M
Tuberk Toraks 2018 Dec;66(4):312-316. doi: 10.5578/tt.67434. PMID: 30683026

Recent clinical studies

Etiology

Endobronchial hamartoma in a young COVID-19 symptomatic woman. Radical endoscopic treatment with a disposable bronchoscope. Case Report.
Guarino C, Cesaro C, La Cerra G, Lucci R, Cesaro F, Zamparelli E, Gaglione G, Pontarelli A, De Rosa A, Parrella R
Monaldi Arch Chest Dis 2021 Dec 16;92(3) doi: 10.4081/monaldi.2021.1822. PMID: 34918499
Efficacy and safety of flexible endoscopic intervention via laryngeal mask airway for endobronchial hamartoma removal.
Song W, Zha W, Qi X, Jiwang W
Minim Invasive Ther Allied Technol 2021 Jun;30(3):139-146. Epub 2020 Feb 3 doi: 10.1080/13645706.2020.1720250. PMID: 32011200
Clinical and characteristic features of surgically treated endobronchial hamartoma cases: analysis of twenty-two cases.
Celik A, Yazici U, Aydin E, Karaoglanoglu N
Clin Ter 2014;165(3):e191-3. doi: 10.7417/CT.2014.1717. PMID: 24999572
Bronchoscopic features and bronchoscopic intervention for endobronchial hamartoma.
Kim SA, Um SW, Song JU, Jeon K, Koh WJ, Suh GY, Jung MP, Kwon OJ, Park JH, Yi CA, Han J, Kim H
Respirology 2010 Jan;15(1):150-4. Epub 2009 Nov 23 doi: 10.1111/j.1440-1843.2009.01662.x. PMID: 19947992
Endobronchial hamartoma.
Cosío BG, Villena V, Echave-Sustaeta J, de Miguel E, Alfaro J, Hernandez L, Sotelo T
Chest 2002 Jul;122(1):202-5. doi: 10.1378/chest.122.1.202. PMID: 12114359

Diagnosis

Endobronchial hamartoma mimicking malignant lung tumor contralateral endobronchial metastasis: A case report.
Chen SS, Zhou H, Tong B, Yu LL, Fan SS, Xiao ZK
Medicine (Baltimore) 2017 Dec;96(49):e9085. doi: 10.1097/MD.0000000000009085. PMID: 29245328Free PMC Article
Multiple endobronchial hamartoma.
Mertoğlu A, Tellioğlu E, Yücel N
Clin Respir J 2017 Mar;11(2):263-266. Epub 2015 Jul 14 doi: 10.1111/crj.12322. PMID: 26076678
Bronchoscopic features and bronchoscopic intervention for endobronchial hamartoma.
Kim SA, Um SW, Song JU, Jeon K, Koh WJ, Suh GY, Jung MP, Kwon OJ, Park JH, Yi CA, Han J, Kim H
Respirology 2010 Jan;15(1):150-4. Epub 2009 Nov 23 doi: 10.1111/j.1440-1843.2009.01662.x. PMID: 19947992
Fat-containing lesions of the chest.
Gaerte SC, Meyer CA, Winer-Muram HT, Tarver RD, Conces DJ Jr
Radiographics 2002 Oct;22 Spec No:S61-78. doi: 10.1148/radiographics.22.suppl_1.g02oc08s61. PMID: 12376601
Endobronchial hamartoma.
Cosío BG, Villena V, Echave-Sustaeta J, de Miguel E, Alfaro J, Hernandez L, Sotelo T
Chest 2002 Jul;122(1):202-5. doi: 10.1378/chest.122.1.202. PMID: 12114359

Therapy

Resection of a endobronchial hamartoma by electrocautery and argon plasma ablation via fiberoptic bronchoscopy.
Jain S, Agrawal D, Shah T, Udwadia ZE
Indian J Chest Dis Allied Sci 2006 Jul-Sep;48(3):217-9. PMID: 18610683

Prognosis

Endobronchial hamartoma as a cause of pneumonia.
Oguma T, Takiguchi H, Niimi K, Tomomatsu H, Tomomatsu K, Hayama N, Aoki T, Urano T, Nakano N, Ogura G, Nakagawa T, Masuda R, Iwazaki M, Abe T, Asano K
Am J Case Rep 2014 Sep 11;15:388-92. doi: 10.12659/AJCR.890869. PMID: 25208559Free PMC Article
Endobronchial hamartoma with obstructive pneumonia due to Nocardia asiatica.
Matsumoto T, Shimizu T, Aoshima Y, Oda H, Kikuchi K, Katsura H, Fujiwara T, Onuki T
Gen Thorac Cardiovasc Surg 2011 Feb;59(2):141-4. Epub 2011 Feb 10 doi: 10.1007/s11748-010-0619-6. PMID: 21308445
Endobronchial lipomatous hamartoma with mediastinal extension.
Tsitouridis I, Michaelides M, Kyriakou V, Arvanity M
J Thorac Imaging 2010 Feb;25(1):W6-9. doi: 10.1097/RTI.0b013e318199fbd5. PMID: 20160589
Management of endobronchial hamartoma.
David O, Beasley MB, Minardi AJ Jr, Malek F, Kovitz KL
J La State Med Soc 2003 Mar-Apr;155(2):110-2. PMID: 12778997
Endobronchial hamartoma. Report of 7 cases.
Borro JM, Moya J, Botella JA, Padilla JD, Canto A, Paris F
Scand J Thorac Cardiovasc Surg 1989;23(3):285-7. doi: 10.3109/14017438909106011. PMID: 2617250

Clinical prediction guides

Can we prevent recurrences in the endoscopic treatment of endobronchial hamartomas?
Aktaş Z, Yılmaz A, Öztürk A, Karataş M
Tuberk Toraks 2018 Dec;66(4):312-316. doi: 10.5578/tt.67434. PMID: 30683026
Clinical and characteristic features of surgically treated endobronchial hamartoma cases: analysis of twenty-two cases.
Celik A, Yazici U, Aydin E, Karaoglanoglu N
Clin Ter 2014;165(3):e191-3. doi: 10.7417/CT.2014.1717. PMID: 24999572

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