U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Acinar lung adenocarcinoma

MedGen UID:
233130
•Concept ID:
C1332137
•
Neoplastic Process
Synonyms: Acinar Adenocarcinoma of Lung; acinar adenocarcinoma of lung; Acinar Adenocarcinoma of the Lung; acinar adenocarcinoma of the lung; acinar lung adenocarcinoma; Lung Acinar Adenocarcinoma; lung acinar adenocarcinoma
 
Monarch Initiative: MONDO:0003892

Definition

A morphologic variant of lung adenocarcinoma characterized by the presence of acinar structures composed of columnar or cuboidal cells. (NCI05) [from NCI]

Professional guidelines

PubMed

Molecular heterogeneity in histomorphologic subtypes of lung adeno carcinoma represents a challenge for treatment decision.
Kolb T, Müller S, Möller P, Barth TFE, Marienfeld R
Neoplasia 2024 Mar;49:100955. Epub 2024 Feb 3 doi: 10.1016/j.neo.2023.100955. PMID: 38310709Free PMC Article
Pulmonary Adenocarcinomas of Low Malignant Potential: Proposed Criteria to Expand the Spectrum Beyond Adenocarcinoma In Situ and Minimally Invasive Adenocarcinoma.
Yambayev I, Sullivan TB, Suzuki K, Zhao Q, Higgins SE, Yilmaz OH, Litle VR, Moreira P, Servais EL, Stock CT, Quadri SM, Williamson C, Rieger-Christ KM, Burks EJ
Am J Surg Pathol 2021 Apr 1;45(4):567-576. doi: 10.1097/PAS.0000000000001618. PMID: 33177339
Lung adenocarcinoma with sarcomatoid transformation after tyrosine kinase inhibitor treatment and chemotherapy.
Hsieh MS, Lin MW, Lee YH
Lung Cancer 2019 Nov;137:76-84. Epub 2019 Aug 26 doi: 10.1016/j.lungcan.2019.08.029. PMID: 31561203

Recent clinical studies

Diagnosis

Spatial transcriptomics reveals heterogeneity of histological subtypes between lepidic and acinar lung adenocarcinoma.
Xie L, Kong H, Yu J, Sun M, Lu S, Zhang Y, Hu J, Du F, Lian Q, Xin H, Zhou J, Wang X, Powell CA, Hirsch FR, Bai C, Song Y, Yin J, Yang D
Clin Transl Med 2024 Feb;14(2):e1573. doi: 10.1002/ctm2.1573. PMID: 38318637Free PMC Article

Therapy

Spatial transcriptomics reveals heterogeneity of histological subtypes between lepidic and acinar lung adenocarcinoma.
Xie L, Kong H, Yu J, Sun M, Lu S, Zhang Y, Hu J, Du F, Lian Q, Xin H, Zhou J, Wang X, Powell CA, Hirsch FR, Bai C, Song Y, Yin J, Yang D
Clin Transl Med 2024 Feb;14(2):e1573. doi: 10.1002/ctm2.1573. PMID: 38318637Free PMC Article

Prognosis

Spatial transcriptomics reveals heterogeneity of histological subtypes between lepidic and acinar lung adenocarcinoma.
Xie L, Kong H, Yu J, Sun M, Lu S, Zhang Y, Hu J, Du F, Lian Q, Xin H, Zhou J, Wang X, Powell CA, Hirsch FR, Bai C, Song Y, Yin J, Yang D
Clin Transl Med 2024 Feb;14(2):e1573. doi: 10.1002/ctm2.1573. PMID: 38318637Free PMC Article
Comparative profiling of single-cell transcriptome reveals heterogeneity of tumor microenvironment between solid and acinar lung adenocarcinoma.
Li D, Yu H, Hu J, Li S, Yan Y, Li S, Sun L, Jiang G, Hou L, Zhang L, Zhang P
J Transl Med 2022 Sep 23;20(1):423. doi: 10.1186/s12967-022-03620-3. PMID: 36138435Free PMC Article

Clinical prediction guides

Spatial transcriptomics reveals heterogeneity of histological subtypes between lepidic and acinar lung adenocarcinoma.
Xie L, Kong H, Yu J, Sun M, Lu S, Zhang Y, Hu J, Du F, Lian Q, Xin H, Zhou J, Wang X, Powell CA, Hirsch FR, Bai C, Song Y, Yin J, Yang D
Clin Transl Med 2024 Feb;14(2):e1573. doi: 10.1002/ctm2.1573. PMID: 38318637Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...