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Mediastinal mesenchymal tumor

MedGen UID:
233171
•Concept ID:
C1334669
•
Neoplastic Process
Synonyms: mediastinal mesenchymal tumor; Mediastinal Soft Tissue Neoplasm; mediastinal soft tissue neoplasm; Mediastinal Soft Tissue Tumor; mediastinal soft tissue tumor; mediastinal soft tissue tumour; Soft Tissue Neoplasm of Mediastinum; soft tissue neoplasm of mediastinum; Soft Tissue Neoplasm of the Mediastinum; soft tissue neoplasm of the mediastinum; Soft Tissue Tumor of Mediastinum; soft tissue tumor of mediastinum; Soft Tissue Tumor of the Mediastinum; soft tissue tumor of the mediastinum; soft tissue tumour of mediastinum; soft tissue tumour of the mediastinum
 
Monarch Initiative: MONDO:0003512

Definition

A benign or malignant mesenchymal neoplasm of the mediastinum. Representative examples of benign mediastinal soft tissue neoplasms include chondroma, leiomyoma, lipoma, and rhabdomyoma. Representative examples of malignant mediastinal soft tissue neoplasms include angiosarcoma, leiomyosarcoma, liposarcoma, osteosarcoma, rhabdomyosarcoma, and synovial sarcoma. [from NCI]

Professional guidelines

PubMed

Management of desmoplastic small round cell tumor.
Hayes-Jordan A, LaQuaglia MP, Modak S
Semin Pediatr Surg 2016 Oct;25(5):299-304. Epub 2016 Sep 14 doi: 10.1053/j.sempedsurg.2016.09.005. PMID: 27955733Free PMC Article
Treatment and prognostic factors in pleuropulmonary blastoma: an EXPeRT report.
Bisogno G, Brennan B, Orbach D, Stachowicz-Stencel T, Cecchetto G, Indolfi P, Bien E, Ferrari A, Dommange-Romero F
Eur J Cancer 2014 Jan;50(1):178-84. Epub 2013 Sep 13 doi: 10.1016/j.ejca.2013.08.015. PMID: 24041875
Differential diagnostic considerations and potential pitfalls in fine-needle aspiration biopsies of the mediastinum.
Geisinger KR
Diagn Cytopathol 1995 Dec;13(5):436-42. doi: 10.1002/dc.2840130512. PMID: 8834318

Recent clinical studies

Diagnosis

A case of mediastinal mesenchymal tumor with pericytic neoplasm feature that responded to radiation therapy.
Muramoto M, Kanda S, Kobayashi T, Tamada H, Fukazawa A, Koiwai K, Koizumi T
Thorac Cancer 2023 May;14(13):1204-1207. Epub 2023 Mar 25 doi: 10.1111/1759-7714.14855. PMID: 36965153Free PMC Article
Thymic Dedifferentiated Liposarcoma Having a Leiomyosarcomatous Dedifferentiated Component.
Miyaoka M, Hatanaka K, Kikuti YY, Masuda R, Iwazaki M, Nakamura N
Tokai J Exp Clin Med 2022 Apr 20;47(1):22-25. PMID: 35383866
CT features of mediastinal lymphangiohemangioma associated with superior vena cava ectasia. A case report.
Wong AM, Wa YL, Cheung YC, Ng SH, Lee KF
Acta Radiol 2000 Sep;41(5):429-31. doi: 10.1080/028418500127345866. PMID: 11016760

Clinical prediction guides

Thymic Dedifferentiated Liposarcoma Having a Leiomyosarcomatous Dedifferentiated Component.
Miyaoka M, Hatanaka K, Kikuti YY, Masuda R, Iwazaki M, Nakamura N
Tokai J Exp Clin Med 2022 Apr 20;47(1):22-25. PMID: 35383866

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