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Normoblastic Erythroid Hyperplasia

MedGen UID:
233250
•Concept ID:
C1335067
•
Finding

Definition

A laboratory test result indicating an abnormally high quantity of immature red blood cells containing hemoglobin and a pyknotic nucleus. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNormoblastic Erythroid Hyperplasia

Professional guidelines

PubMed

Clinical course and results of treatment of erythroleukaemia.
Frydecka I, Brodzka W, Lawińska B, Sciborski R
Folia Haematol Int Mag Klin Morphol Blutforsch 1984;111(3):283-9. PMID: 6205951

Recent clinical studies

Etiology

Congenital dyserythropoietic anemia, type II with SEC23B exon 12 c.1385 A → G mutation, and pseudo-Gaucher cells in two siblings.
Sharma P, Das R, Bansal D, Trehan A
Hematology 2015 Mar;20(2):104-7. Epub 2014 May 6 doi: 10.1179/1607845414Y.0000000166. PMID: 24801240

Diagnosis

Congenital dyserythropoietic anemia, type II with SEC23B exon 12 c.1385 A → G mutation, and pseudo-Gaucher cells in two siblings.
Sharma P, Das R, Bansal D, Trehan A
Hematology 2015 Mar;20(2):104-7. Epub 2014 May 6 doi: 10.1179/1607845414Y.0000000166. PMID: 24801240
Paroxysmal nocturnal hemoglobinuria in childhood: an uncommon presentation.
Gupta V, Tilak V, Ramakrishna SV, Bhatia BD
Indian J Med Sci 2006 Feb;60(2):64-7. PMID: 16505576
Amegakaryocytic thrombocytopenia with a positive direct Coombs' test.
Koduri PR
Am J Hematol 1993 Sep;44(1):68-9. doi: 10.1002/ajh.2830440116. PMID: 8342568

Therapy

Amegakaryocytic thrombocytopenia with a positive direct Coombs' test.
Koduri PR
Am J Hematol 1993 Sep;44(1):68-9. doi: 10.1002/ajh.2830440116. PMID: 8342568

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