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Adenosquamous prostate carcinoma

MedGen UID:: 233353
•Concept ID:: C1335503
•: Neoplastic Process

Synonyms:	Adenosquamous Carcinoma of Prostate; adenosquamous carcinoma of prostate; Adenosquamous Carcinoma of the Prostate; adenosquamous carcinoma of the prostate; adenosquamous prostate carcinoma; Prostate Adenosquamous Carcinoma; prostate adenosquamous carcinoma; prostate gland adenosquamous carcinoma

Monarch Initiative:	MONDO:0003558

Definition

An infrequent invasive carcinoma of the prostate gland characterized by the presence of both glandular and squamous neoplastic components. It is more often located in the transitional zone of the prostate gland and it tends to rapidly metastasize to the bones. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAdenosquamous prostate carcinoma

Neoplasm
- Neoplasm by Special Category
  - Malignant neoplastic disease
    - Invasive Malignant Neoplasm
      - Invasive carcinoma
        Invasive Prostate Carcinoma
        Adenosquamous prostate carcinoma

Professional guidelines

PubMed

Uncommon Cervical Lesions: A Review and Discussion of the Differential Diagnosis.

Griesinger LM, Szczepanski JM, McMullen ER, Skala SL
Arch Pathol Lab Med 2021 Jul 1;145(7):891-902. doi: 10.5858/arpa.2020-0327-RA. PMID: 33091926

Histologic variants of adenocarcinoma and other carcinomas of prostate: pathologic criteria and clinical significance.

Randolph TL, Amin MB, Ro JY, Ayala AG
Mod Pathol 1997 Jun;10(6):612-29. PMID: 9195581

See all (2)

Recent clinical studies

Etiology

The relationship between HER2 expression and (18)F-FDG in gastric carcinoma.

Ozen A, Tatar G
Hell J Nucl Med 2022 Jan-Apr;25(1):5-10. Epub 2022 Apr 8 doi: 10.1967/s002449912430. PMID: 35388798

Histologic classification of prostate cancer.

Mikuz G
Anal Quant Cytopathol Histpathol 2015 Feb;37(1):39-47. PMID: 26072633

Histological variants of prostatic carcinoma and their significance.

Humphrey PA
Histopathology 2012 Jan;60(1):59-74. doi: 10.1111/j.1365-2559.2011.04039.x. PMID: 22212078

Clinicopathological characteristics of resected adenosquamous cell carcinoma of the lung: risk of coexistent double cancer.

Uramoto H, Yamada S, Hanagiri T
J Cardiothorac Surg 2010 Oct 29;5:92. doi: 10.1186/1749-8090-5-92. PMID: 21034441 Free PMC Article

Non-solid oncogenes in solid tumors: EML4-ALK fusion genes in lung cancer.

Mano H
Cancer Sci 2008 Dec;99(12):2349-55. Epub 2008 Nov 20 doi: 10.1111/j.1349-7006.2008.00972.x. PMID: 19032370

See all (11)

Diagnosis

Histological patterns, subtypes and aspects of prostate cancer: different aspects, different outcomes.

Wasinger G, Oszwald A, Shariat SF, Compérat E
Curr Opin Urol 2022 Nov 1;32(6):643-648. Epub 2022 Sep 8 doi: 10.1097/MOU.0000000000001038. PMID: 36081403

Uncommon Cervical Lesions: A Review and Discussion of the Differential Diagnosis.

Griesinger LM, Szczepanski JM, McMullen ER, Skala SL
Arch Pathol Lab Med 2021 Jul 1;145(7):891-902. doi: 10.5858/arpa.2020-0327-RA. PMID: 33091926

Histological variants of prostatic carcinoma and their significance.

Humphrey PA
Histopathology 2012 Jan;60(1):59-74. doi: 10.1111/j.1365-2559.2011.04039.x. PMID: 22212078

Histologic variants of adenocarcinoma and other carcinomas of prostate: pathologic criteria and clinical significance.

Randolph TL, Amin MB, Ro JY, Ayala AG
Mod Pathol 1997 Jun;10(6):612-29. PMID: 9195581

Adenosquamous carcinoma of prostate.

Accetta PA, Gardner WA Jr
Urology 1983 Jul;22(1):73-5. doi: 10.1016/0090-4295(83)90355-2. PMID: 6346632

See all (34)

Therapy

Efficacy and oncologic safety of nerve-sparing radical hysterectomy for cervical cancer: a randomized controlled trial.

Roh JW, Lee DO, Suh DH, Lim MC, Seo SS, Chung J, Lee S, Park SY
J Gynecol Oncol 2015 Apr;26(2):90-9. doi: 10.3802/jgo.2015.26.2.90. PMID: 25872890 Free PMC Article

Four primary tumors of lung, bladder, prostate, and breast in a male patient.

Otrock ZK, Mahfouz RA, Salem ZM
South Med J 2005 Sep;98(9):946-9. doi: 10.1097/01.smj.0000173086.37625.e2. PMID: 16217994

Adenosquamous carcinoma of the prostate: a case report.

Devaney DM, Dorman A, Leader M
Hum Pathol 1991 Oct;22(10):1046-50. doi: 10.1016/0046-8177(91)90014-g. PMID: 1842377

Adenosquamous carcinoma of prostate.

Accetta PA, Gardner WA Jr
Urology 1983 Jul;22(1):73-5. doi: 10.1016/0090-4295(83)90355-2. PMID: 6346632

See all (4)

Prognosis

Histological patterns, subtypes and aspects of prostate cancer: different aspects, different outcomes.

Wasinger G, Oszwald A, Shariat SF, Compérat E
Curr Opin Urol 2022 Nov 1;32(6):643-648. Epub 2022 Sep 8 doi: 10.1097/MOU.0000000000001038. PMID: 36081403

Uncommon Cervical Lesions: A Review and Discussion of the Differential Diagnosis.

Griesinger LM, Szczepanski JM, McMullen ER, Skala SL
Arch Pathol Lab Med 2021 Jul 1;145(7):891-902. doi: 10.5858/arpa.2020-0327-RA. PMID: 33091926

Rare Histological Variants of Prostate Adenocarcinoma: A National Cancer Database Analysis.

Bronkema C, Arora S, Sood A, Dalela D, Keeley J, Borchert A, Baumgarten L, Rogers CG, Peabody JO, Menon M, Abdollah F
J Urol 2020 Aug;204(2):260-266. Epub 2020 Mar 6 doi: 10.1097/JU.0000000000001011. PMID: 32141804

Histologic classification of prostate cancer.

Mikuz G
Anal Quant Cytopathol Histpathol 2015 Feb;37(1):39-47. PMID: 26072633

Adenosquamous carcinoma of the prostate: case report with DNA analysis, immunohistochemistry, and literature review.

Bassler TJ Jr, Orozco R, Bassler IC, Boyle LM, Bormes T
Urology 1999 Apr;53(4):832-4. doi: 10.1016/s0090-4295(98)00418-x. PMID: 10197870

See all (19)