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Prostate stromal sarcoma

MedGen UID:
233359
•Concept ID:
C1335521
•
Neoplastic Process
Synonyms: Prostate Stromal Sarcoma; prostate stromal sarcoma; Stromal Sarcoma of Prostate; stromal sarcoma of prostate; Stromal Sarcoma of the Prostate; stromal sarcoma of the prostate
 
Monarch Initiative: MONDO:0004124

Definition

A rare malignant neoplasm arising from specialized prostatic stroma. It is characterized by the presence of stromal overgrowth and hypercellularity, increased number of mitotic figures, and pleomorphism. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProstate stromal sarcoma

Professional guidelines

PubMed

Management of Recurrent Retroperitoneal Sarcoma (RPS) in the Adult: A Consensus Approach from the Trans-Atlantic RPS Working Group.
Trans-Atlantic RPS Working Group
Ann Surg Oncol 2016 Oct;23(11):3531-3540. Epub 2016 Aug 1 doi: 10.1245/s10434-016-5336-7. PMID: 27480354Free PMC Article
Beyond Prostate Adenocarcinoma: Expanding the Differential Diagnosis in Prostate Pathologic Conditions.
Li Y, Mongan J, Behr SC, Sud S, Coakley FV, Simko J, Westphalen AC
Radiographics 2016 Jul-Aug;36(4):1055-75. Epub 2016 Jun 17 doi: 10.1148/rg.2016150226. PMID: 27315446
The utility of STAT6 and ALDH1 expression in the differential diagnosis of solitary fibrous tumor versus prostate-specific stromal neoplasms.
Guner G, Bishop JA, Bezerra SM, Taheri D, Zahavi DJ, Mendoza Rodriguez MA, Sharma R, Epstein JI, Netto GJ
Hum Pathol 2016 Aug;54:184-8. Epub 2016 Apr 8 doi: 10.1016/j.humpath.2016.03.011. PMID: 27068523

Recent clinical studies

Etiology

Clinical and Pathological Features of Prostatic Stromal Tumor of Uncertain Malignant Potential: A Retrospective Study of 23 Chinese Cases.
Shen Q, Zhou Z, Liu Z, Hu S, Lin Z, Li S, Li S, Song H, Chen Y, Meng Y, Wang Y, Fan Y, Li X, Xiao Y, He Q, Jin J, Zhang Q, Yu W
Urol Int 2021;105(3-4):206-214. Epub 2020 Nov 20 doi: 10.1159/000508763. PMID: 33221793

Diagnosis

Clinical and Pathological Features of Prostatic Stromal Tumor of Uncertain Malignant Potential: A Retrospective Study of 23 Chinese Cases.
Shen Q, Zhou Z, Liu Z, Hu S, Lin Z, Li S, Li S, Song H, Chen Y, Meng Y, Wang Y, Fan Y, Li X, Xiao Y, He Q, Jin J, Zhang Q, Yu W
Urol Int 2021;105(3-4):206-214. Epub 2020 Nov 20 doi: 10.1159/000508763. PMID: 33221793
Synchronous prostate stromal sarcoma and gastrointestinal stromal tumor of rectum: case report and review of the literature.
Huang YC, Wang JY, Lin PY, Chin CC, Chen CS
Urology 2006 Sep;68(3):672.e11-3. Epub 2006 Sep 18 doi: 10.1016/j.urology.2006.03.018. PMID: 16979698

Prognosis

Clinical and Pathological Features of Prostatic Stromal Tumor of Uncertain Malignant Potential: A Retrospective Study of 23 Chinese Cases.
Shen Q, Zhou Z, Liu Z, Hu S, Lin Z, Li S, Li S, Song H, Chen Y, Meng Y, Wang Y, Fan Y, Li X, Xiao Y, He Q, Jin J, Zhang Q, Yu W
Urol Int 2021;105(3-4):206-214. Epub 2020 Nov 20 doi: 10.1159/000508763. PMID: 33221793

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