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Breast Micropapillary Ductal Carcinoma In Situ

MedGen UID:
233571
•Concept ID:
C1334249
•
Neoplastic Process
Synonyms: Breast Intraductal Micropapillary Carcinoma; Breast Micropapillary DCIS; Intraductal Micropapillary Breast Carcinoma; Micropapillary DCIS of Breast; Micropapillary DCIS of the Breast; Micropapillary Ductal Breast Carcinoma in situ; Micropapillary Ductal Carcinoma In Situ; Micropapillary Ductal Carcinoma in situ of Breast; Micropapillary Ductal Carcinoma in situ of the Breast; Non-Infiltrating Micropapillary Breast Carcinoma; Non-Infiltrating Micropapillary Carcinoma of Breast; Non-Infiltrating Micropapillary Carcinoma of the Breast; Non-Infiltrating Micropapillary Ductal Breast Carcinoma; Non-Infiltrating Micropapillary Ductal Carcinoma of Breast; Non-Infiltrating Micropapillary Ductal Carcinoma of the Breast; Non-Invasive Micropapillary Breast Carcinoma; Non-Invasive Micropapillary Carcinoma of Breast; Non-Invasive Micropapillary Carcinoma of the Breast; Non-Invasive Micropapillary Ductal Breast Carcinoma; Non-Invasive Micropapillary Ductal Carcinoma of Breast; Non-Invasive Micropapillary Ductal Carcinoma of the Breast

Definition

Breast ductal carcinoma in situ characterized by the presence of neoplastic epithelial cells arranged in micropapillary patterns. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBreast Micropapillary Ductal Carcinoma In Situ

Professional guidelines

PubMed

Flat ductal intraepithelial neoplasia of the breast: a review of diagnostic criteria, differential diagnoses, molecular-genetic findings, and clinical relevance--it is time to appreciate the Azzopardi concept!
Moinfar F
Arch Pathol Lab Med 2009 Jun;133(6):879-92. doi: 10.5858/133.6.879. PMID: 19492880
Aggressive local treatment for screen-detected DCIS results in very low rates of recurrence.
Jha MK, Avlonitis VS, Griffith CD, Lennard TW, Wilson RG, McLean LM, Dawes PD, Shrimankar J
Eur J Surg Oncol 2001 Aug;27(5):454-8. doi: 10.1053/ejso.2001.1163. PMID: 11504515
Nonpalpable in situ ductal carcinoma of the breast. Predictors of multicentricity and microinvasion and implications for treatment.
Schwartz GF, Patchefsky AS, Finklestein SD, Sohn SH, Prestipino A, Feig SA, Singer JS
Arch Surg 1989 Jan;124(1):29-32. doi: 10.1001/archsurg.1989.01410010035007. PMID: 2535928

Recent clinical studies

Etiology

Papillary lesions of the breast.
Kulka J, Madaras L, Floris G, Lax SF
Virchows Arch 2022 Jan;480(1):65-84. Epub 2021 Nov 3 doi: 10.1007/s00428-021-03182-7. PMID: 34734332Free PMC Article
Triple-Positive Breast Carcinoma: Histopathologic Features and Response to Neoadjuvant Chemotherapy.
Zeng J, Edelweiss M, Ross DS, Xu B, Moo TA, Brogi E, D'Alfonso TM
Arch Pathol Lab Med 2021 Jun 1;145(6):728-735. doi: 10.5858/arpa.2020-0293-OA. PMID: 33112958Free PMC Article
Ipsilateral and Concurrent Breast Cancer and Atypical Ductal Hyperplasia: Does Atypia Also Need Surgical Excision?
Amin AL, Fan F, Winblad OD, Larson KE, Wagner JL
Ann Surg Oncol 2020 Nov;27(12):4786-4794. Epub 2020 Jul 23 doi: 10.1245/s10434-020-08896-7. PMID: 32705514
Micropapillary ductal carcinoma in situ of the breast: an inter-institutional study.
Castellano I, Marchiò C, Tomatis M, Ponti A, Casella D, Bianchi S, Vezzosi V, Arisio R, Pietribiasi F, Frigerio A, Mano MP, Ricardi U, Allia E, Accortanzo V, Durando A, Bussolati G, Tot T, Sapino A
Mod Pathol 2010 Feb;23(2):260-9. Epub 2009 Nov 13 doi: 10.1038/modpathol.2009.169. PMID: 19915523
Ductal carcinoma in situ: a proposal for a new classification.
Holland R, Peterse JL, Millis RR, Eusebi V, Faverly D, van de Vijver MJ, Zafrani B
Semin Diagn Pathol 1994 Aug;11(3):167-80. PMID: 7831528

Diagnosis

The Spectrum of Mucinous Lesions of the Breast.
Joneja U, Palazzo J
Arch Pathol Lab Med 2023 Jan 1;147(1):19-29. doi: 10.5858/arpa.2022-0054-RA. PMID: 36577093
Papillary lesions of the breast.
Kulka J, Madaras L, Floris G, Lax SF
Virchows Arch 2022 Jan;480(1):65-84. Epub 2021 Nov 3 doi: 10.1007/s00428-021-03182-7. PMID: 34734332Free PMC Article
Apocrine lesions of the breast.
Quinn CM, D'Arcy C, Wells C
Virchows Arch 2022 Jan;480(1):177-189. Epub 2021 Sep 18 doi: 10.1007/s00428-021-03185-4. PMID: 34537861Free PMC Article
Ipsilateral and Concurrent Breast Cancer and Atypical Ductal Hyperplasia: Does Atypia Also Need Surgical Excision?
Amin AL, Fan F, Winblad OD, Larson KE, Wagner JL
Ann Surg Oncol 2020 Nov;27(12):4786-4794. Epub 2020 Jul 23 doi: 10.1245/s10434-020-08896-7. PMID: 32705514
Noninvasive papillary proliferations.
Oyama T, Koerner FC
Semin Diagn Pathol 2004 Feb;21(1):32-41. doi: 10.1053/j.semdp.2003.10.011. PMID: 15074557

Therapy

Triple-Positive Breast Carcinoma: Histopathologic Features and Response to Neoadjuvant Chemotherapy.
Zeng J, Edelweiss M, Ross DS, Xu B, Moo TA, Brogi E, D'Alfonso TM
Arch Pathol Lab Med 2021 Jun 1;145(6):728-735. doi: 10.5858/arpa.2020-0293-OA. PMID: 33112958Free PMC Article
Secondary breast carcinoma after completely remitted chronic myeloid leukemia following targeted tyrosine kinase inhibitor therapy.
Pan L, Duan J, Qiao W, Bi L, Wu D, Fan Z, Yang M
Breast Cancer 2017 Nov;24(6):790-793. Epub 2017 Jun 5 doi: 10.1007/s12282-017-0786-8. PMID: 28585003
Intracystic papillary carcinoma of the male breast: a case report and review of the literature.
Hussain A, Sweeney KJ, Salman R, Callagy GM, Sweeney I, McLaughlin R
Ir J Med Sci 2012 Sep;181(3):329-31. Epub 2009 Jul 9 doi: 10.1007/s11845-009-0372-y. PMID: 19588226
Breast-conserving treatment with or without radiotherapy in ductal carcinoma-in-situ: ten-year results of European Organisation for Research and Treatment of Cancer randomized phase III trial 10853--a study by the EORTC Breast Cancer Cooperative Group and EORTC Radiotherapy Group.
EORTC Breast Cancer Cooperative Group; EORTC Radiotherapy Group, Bijker N, Meijnen P, Peterse JL, Bogaerts J, Van Hoorebeeck I, Julien JP, Gennaro M, Rouanet P, Avril A, Fentiman IS, Bartelink H, Rutgers EJ
J Clin Oncol 2006 Jul 20;24(21):3381-7. Epub 2006 Jun 26 doi: 10.1200/JCO.2006.06.1366. PMID: 16801628
Sentinel node biopsy in ductal carcinoma in situ patients.
Pendas S, Dauway E, Giuliano R, Ku N, Cox CE, Reintgen DS
Ann Surg Oncol 2000 Jan-Feb;7(1):15-20. doi: 10.1007/s10434-000-0015-z. PMID: 10674443

Prognosis

The Spectrum of Mucinous Lesions of the Breast.
Joneja U, Palazzo J
Arch Pathol Lab Med 2023 Jan 1;147(1):19-29. doi: 10.5858/arpa.2022-0054-RA. PMID: 36577093
Triple-Positive Breast Carcinoma: Histopathologic Features and Response to Neoadjuvant Chemotherapy.
Zeng J, Edelweiss M, Ross DS, Xu B, Moo TA, Brogi E, D'Alfonso TM
Arch Pathol Lab Med 2021 Jun 1;145(6):728-735. doi: 10.5858/arpa.2020-0293-OA. PMID: 33112958Free PMC Article
Comparison of clinicopathological characteristics and prognosis among patients with pure invasive ductal carcinoma, invasive ductal carcinoma coexisted with invasive micropapillary carcinoma, and invasive ductal carcinoma coexisted with ductal carcinoma in situ: A retrospective cohort study.
Guan X, Xu G, Shi A, Zou Y, Zhan Y, Fan Z, Dong Y
Medicine (Baltimore) 2020 Dec 11;99(50):e23487. doi: 10.1097/MD.0000000000023487. PMID: 33327281Free PMC Article
Ipsilateral and Concurrent Breast Cancer and Atypical Ductal Hyperplasia: Does Atypia Also Need Surgical Excision?
Amin AL, Fan F, Winblad OD, Larson KE, Wagner JL
Ann Surg Oncol 2020 Nov;27(12):4786-4794. Epub 2020 Jul 23 doi: 10.1245/s10434-020-08896-7. PMID: 32705514
Papillary neoplasms of the breast: a review.
Ueng SH, Mezzetti T, Tavassoli FA
Arch Pathol Lab Med 2009 Jun;133(6):893-907. doi: 10.5858/133.6.893. PMID: 19492881

Clinical prediction guides

Papillary lesions of the breast.
Kulka J, Madaras L, Floris G, Lax SF
Virchows Arch 2022 Jan;480(1):65-84. Epub 2021 Nov 3 doi: 10.1007/s00428-021-03182-7. PMID: 34734332Free PMC Article
Triple-Positive Breast Carcinoma: Histopathologic Features and Response to Neoadjuvant Chemotherapy.
Zeng J, Edelweiss M, Ross DS, Xu B, Moo TA, Brogi E, D'Alfonso TM
Arch Pathol Lab Med 2021 Jun 1;145(6):728-735. doi: 10.5858/arpa.2020-0293-OA. PMID: 33112958Free PMC Article
Ipsilateral and Concurrent Breast Cancer and Atypical Ductal Hyperplasia: Does Atypia Also Need Surgical Excision?
Amin AL, Fan F, Winblad OD, Larson KE, Wagner JL
Ann Surg Oncol 2020 Nov;27(12):4786-4794. Epub 2020 Jul 23 doi: 10.1245/s10434-020-08896-7. PMID: 32705514
Ductal carcinoma in situ of the breast: correlation between histopathological features and age of patients.
Perez AA, Balabram D, Salles Mde A, Gobbi H
Diagn Pathol 2014 Dec 3;9:227. doi: 10.1186/s13000-014-0227-3. PMID: 25471940Free PMC Article
Noninvasive papillary proliferations.
Oyama T, Koerner FC
Semin Diagn Pathol 2004 Feb;21(1):32-41. doi: 10.1053/j.semdp.2003.10.011. PMID: 15074557

Recent systematic reviews

Exploring female medical students' knowledge, attitudes, practices, and perceptions related to breast cancer screening: a scoping review.
Tomic M, Vescan ML, Ungureanu MI
J Med Life 2023 Dec;16(12):1732-1739. doi: 10.25122/jml-2023-0412. PMID: 38585536Free PMC Article

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