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Moderately Differentiated Prostate Adenocarcinoma

MedGen UID:
233715
•Concept ID:
C1334792
•
Neoplastic Process

Definition

An invasive prostate adenocarcinoma characterized by the presence of malignant cells exhibiting moderate differentiation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVModerately Differentiated Prostate Adenocarcinoma

Professional guidelines

PubMed

Best practices recommendations in the application of immunohistochemistry in the prostate: report from the International Society of Urologic Pathology consensus conference.
Epstein JI, Egevad L, Humphrey PA, Montironi R; Members of the ISUP Immunohistochemistry in Diagnostic Urologic Pathology Group
Am J Surg Pathol 2014 Aug;38(8):e6-e19. doi: 10.1097/PAS.0000000000000238. PMID: 25029122
Active monitoring (deferred treatment or watchful waiting) in the treatment of prostate cancer. A review.
Schmid HP, Adolfsson J, Aus G
Eur Urol 2001 Nov;40(5):488-94. doi: 10.1159/000049824. PMID: 11752854
Criteria for biopsy diagnosis of minimal volume prostatic adenocarcinoma: analytic comparison with nondiagnostic but suspicious atypical small acinar proliferation.
Iczkowski KA, Bostwick DG
Arch Pathol Lab Med 2000 Jan;124(1):98-107. doi: 10.5858/2000-124-0098-CFBDOM. PMID: 10629139

Recent clinical studies

Etiology

Natural course of clinically localized prostate adenocarcinoma in men less than 70 years old.
Adolfsson J, Carstensen J
J Urol 1991 Jul;146(1):96-8. doi: 10.1016/s0022-5347(17)37722-4. PMID: 2056609

Diagnosis

Natural course of clinically localized prostate adenocarcinoma in men less than 70 years old.
Adolfsson J, Carstensen J
J Urol 1991 Jul;146(1):96-8. doi: 10.1016/s0022-5347(17)37722-4. PMID: 2056609

Prognosis

Natural course of clinically localized prostate adenocarcinoma in men less than 70 years old.
Adolfsson J, Carstensen J
J Urol 1991 Jul;146(1):96-8. doi: 10.1016/s0022-5347(17)37722-4. PMID: 2056609

Clinical prediction guides

Expression of inducible nitric oxide synthase in paired neoplastic and non-neoplastic primary prostate cell cultures and prostatectomy specimen.
Wang J, Torbenson M, Wang Q, Ro JY, Becich M
Urol Oncol 2003 Mar-Apr;21(2):117-22. doi: 10.1016/s1078-1439(02)00208-9. PMID: 12856639

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