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Non-Neoplastic Paranasal Sinus Disorder

MedGen UID:
233775
•Concept ID:
C1335027
•
Disease or Syndrome
Synonym: Non-Neoplastic Paranasal Sinus Disease

Definition

A non-neoplastic disorder that affects the paranasal sinuses. Representative examples include sinusitis and mucocele. [from NCI]

Professional guidelines

PubMed

Non-neoplastic cystic lesions of the sellar region presentation, diagnosis and management of eight cases and review of the literature.
Iqbal J, Kanaan I, Al Homsi M
Acta Neurochir (Wien) 1999;141(4):389-97; discussion 397-8. doi: 10.1007/s007010050315. PMID: 10352749

Recent clinical studies

Etiology

Mucin receptors in chronic rhinosinusitis with nasal polyps.
Bedir A, Özgür A, Bakırtaş M, Özdemir D, Mehel DM, Akgül G, Çelebi M
Acta Otolaryngol 2022 Jul-Aug;142(7-8):585-589. Epub 2022 Sep 15 doi: 10.1080/00016489.2022.2116487. PMID: 36106988
CD163 Immunohistochemical "Circle Sign" Staining Pattern Differentiates Sinonasal Papillomas From Morphologically Similar Non-neoplastic Lesions.
Sterling BC, Mehrad M, Ely KA, Lewis JS Jr
Am J Surg Pathol 2022 Nov 1;46(11):1507-1513. Epub 2022 Aug 23 doi: 10.1097/PAS.0000000000001953. PMID: 35993580Free PMC Article
Sinonasal organized hematoma: Clinical features of seventeen cases and a systematic review.
Choi SJ, Seo ST, Rha KS, Kim YM
Laryngoscope 2015 Sep;125(9):2027-33. Epub 2015 Feb 13 doi: 10.1002/lary.25200. PMID: 25682739
Benign sinonasal masses: a clinicopathological and radiological profile.
Nepal A, Chettri ST, Joshi JJ, Karki S
Kathmandu Univ Med J (KUMJ) 2013 Jan-Mar;11(41):4-8. doi: 10.3126/kumj.v11i1.11015. PMID: 23774404
Organized hematoma in the paranasal sinus and nasal cavity--imaging diagnosis and pathological findings.
Omura G, Watanabe K, Fujishiro Y, Ebihara Y, Nakao K, Asakage T
Auris Nasus Larynx 2010 Apr;37(2):173-7. Epub 2009 Aug 20 doi: 10.1016/j.anl.2009.06.009. PMID: 19699045

Diagnosis

Mucin receptors in chronic rhinosinusitis with nasal polyps.
Bedir A, Özgür A, Bakırtaş M, Özdemir D, Mehel DM, Akgül G, Çelebi M
Acta Otolaryngol 2022 Jul-Aug;142(7-8):585-589. Epub 2022 Sep 15 doi: 10.1080/00016489.2022.2116487. PMID: 36106988
Organized hematoma in the paranasal sinus and nasal cavity--imaging diagnosis and pathological findings.
Omura G, Watanabe K, Fujishiro Y, Ebihara Y, Nakao K, Asakage T
Auris Nasus Larynx 2010 Apr;37(2):173-7. Epub 2009 Aug 20 doi: 10.1016/j.anl.2009.06.009. PMID: 19699045
Clinicopathological study of non-neoplastic lesions of nasal cavity and paranasal sinuses.
Zafar U, Khan N, Afroz N, Hasan SA
Indian J Pathol Microbiol 2008 Jan-Mar;51(1):26-9. doi: 10.4103/0377-4929.40386. PMID: 18417845
Non-neoplastic cystic lesions of the sellar region presentation, diagnosis and management of eight cases and review of the literature.
Iqbal J, Kanaan I, Al Homsi M
Acta Neurochir (Wien) 1999;141(4):389-97; discussion 397-8. doi: 10.1007/s007010050315. PMID: 10352749
Paranasal sinus radiography.
MacLeod B
Emerg Med Clin North Am 1991 Nov;9(4):743-55. PMID: 1915046

Therapy

Radiation therapy: posterior segment complications.
Seregard S, Pelayes DE, Singh AD
Dev Ophthalmol 2013;52:114-23. Epub 2013 Aug 26 doi: 10.1159/000351088. PMID: 23989132

Prognosis

CD163 Immunohistochemical "Circle Sign" Staining Pattern Differentiates Sinonasal Papillomas From Morphologically Similar Non-neoplastic Lesions.
Sterling BC, Mehrad M, Ely KA, Lewis JS Jr
Am J Surg Pathol 2022 Nov 1;46(11):1507-1513. Epub 2022 Aug 23 doi: 10.1097/PAS.0000000000001953. PMID: 35993580Free PMC Article
Human Papilloma Virus (HPV) in Sinonasal Papillomas and Squamous Cell Carcinomas: A PCR-based Study of 60 cases.
Beigh A, Rashi R, Junaid S, Khuroo MS, Farook S
Gulf J Oncolog 2018 Jan;1(26):37-42. PMID: 29607821
Clinicopathological study of non-neoplastic lesions of nasal cavity and paranasal sinuses.
Zafar U, Khan N, Afroz N, Hasan SA
Indian J Pathol Microbiol 2008 Jan-Mar;51(1):26-9. doi: 10.4103/0377-4929.40386. PMID: 18417845
Inflammatory pseudotumour (plasma cell granuloma) arising in the maxillary sinus.
Maruya S, Kurotaki H, Hashimoto T, Ohta S, Shinkawa H, Yagihashi S
Acta Otolaryngol 2005 Mar;125(3):322-7. doi: 10.1080/00016480410022994. PMID: 15966706
Giant cell reparative granuloma of the occipital bone.
Santos-Briz A, Lobato RD, Ramos A, Millán JM, Ricoy JR, Martínez-Tello FJ
Skeletal Radiol 2003 Mar;32(3):151-5. Epub 2002 Dec 7 doi: 10.1007/s00256-002-0563-3. PMID: 12605280

Clinical prediction guides

CD163 Immunohistochemical "Circle Sign" Staining Pattern Differentiates Sinonasal Papillomas From Morphologically Similar Non-neoplastic Lesions.
Sterling BC, Mehrad M, Ely KA, Lewis JS Jr
Am J Surg Pathol 2022 Nov 1;46(11):1507-1513. Epub 2022 Aug 23 doi: 10.1097/PAS.0000000000001953. PMID: 35993580Free PMC Article
Human Papilloma Virus (HPV) in Sinonasal Papillomas and Squamous Cell Carcinomas: A PCR-based Study of 60 cases.
Beigh A, Rashi R, Junaid S, Khuroo MS, Farook S
Gulf J Oncolog 2018 Jan;1(26):37-42. PMID: 29607821
Enhanced podoplanin expression in chronic maxillary sinusitis.
Zustin J, Scheuer HA, Knecht R, Friedrich RE
In Vivo 2013 Jul-Aug;27(4):551-4. PMID: 23812230
Benign sinonasal masses: a clinicopathological and radiological profile.
Nepal A, Chettri ST, Joshi JJ, Karki S
Kathmandu Univ Med J (KUMJ) 2013 Jan-Mar;11(41):4-8. doi: 10.3126/kumj.v11i1.11015. PMID: 23774404
Hematoma-like mass of the maxillary sinus.
Yagisawa M, Ishitoya J, Tsukuda M
Acta Otolaryngol 2006 Mar;126(3):277-81. doi: 10.1080/00016480500316746. PMID: 16618654

Recent systematic reviews

Sinonasal organized hematoma: Clinical features of seventeen cases and a systematic review.
Choi SJ, Seo ST, Rha KS, Kim YM
Laryngoscope 2015 Sep;125(9):2027-33. Epub 2015 Feb 13 doi: 10.1002/lary.25200. PMID: 25682739

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