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Cerebral Non-Hodgkin Lymphoma

MedGen UID:
234112
•Concept ID:
C1332909
•
Neoplastic Process
Synonyms: Cerebral Non-Hodgkin's Lymphoma; Primary Cerebral Non-Hodgkin Lymphoma; Primary Cerebral Non-Hodgkin's Lymphoma

Definition

A non-Hodgkin lymphoma that arises in the cerebral hemispheres as a primary lesion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCerebral Non-Hodgkin Lymphoma

Professional guidelines

PubMed

Prevention and management of secondary central nervous system lymphoma.
Bobillo S, Khwaja J, Ferreri AJM, Cwynarski K
Haematologica 2023 Mar 1;108(3):673-689. doi: 10.3324/haematol.2022.281457. PMID: 36384246Free PMC Article
Treatment Options for Recurrent Primary CNS Lymphoma.
Kaulen LD, Baehring JM
Curr Treat Options Oncol 2022 Nov;23(11):1548-1565. Epub 2022 Oct 7 doi: 10.1007/s11864-022-01016-5. PMID: 36205806
Rituximab for the treatment of multiple sclerosis: a review.
Chisari CG, Sgarlata E, Arena S, Toscano S, Luca M, Patti F
J Neurol 2022 Jan;269(1):159-183. Epub 2021 Jan 8 doi: 10.1007/s00415-020-10362-z. PMID: 33416999Free PMC Article

Recent clinical studies

Etiology

Methotrexate Drug Monitoring From Central Access: Can Blood Sample Collection From Central Venous Access Replace Peripheral Venipuncture in Adults?
Aydilek E, Schanz J, Brökers N
Ther Drug Monit 2023 Jun 1;45(3):364-367. Epub 2023 Feb 28 doi: 10.1097/FTD.0000000000001080. PMID: 36863027
A medical research council randomized trial in patients with primary cerebral non-Hodgkin lymphoma: cerebral radiotherapy with and without cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy.
Mead GM, Bleehen NM, Gregor A, Bullimore J, Shirley D, Rampling RP, Trevor J, Glaser MG, Lantos P, Ironside JW, Moss TH, Brada M, Whaley JB, Stenning SP
Cancer 2000 Sep 15;89(6):1359-70. PMID: 11002232

Diagnosis

Primary central nervous system lymphoma in the SMA presenting as rapidly progressive parkinsonism.
Haussermann P, Wilhelm T, Keinath S, Stölzle C, Conrad B, Ceballos-Baumann A
Mov Disord 2001 Sep;16(5):962-5. doi: 10.1002/mds.1193. PMID: 11746632
Primary cerebral anaplastic T-cell-lymphoma (type Ki-1): review and case report.
Feldges A, Gerhard L, Reinhardt V, Budach V
Clin Neuropathol 1992 Mar-Apr;11(2):55-9. PMID: 1318814
CT features of primary cerebral lymphoma in AIDS and non-AIDS patients.
Poon T, Matoso I, Tchertkoff V, Weitzner I Jr, Gade M
J Comput Assist Tomogr 1989 Jan-Feb;13(1):6-9. doi: 10.1097/00004728-198901000-00002. PMID: 2642924

Therapy

Methotrexate Drug Monitoring From Central Access: Can Blood Sample Collection From Central Venous Access Replace Peripheral Venipuncture in Adults?
Aydilek E, Schanz J, Brökers N
Ther Drug Monit 2023 Jun 1;45(3):364-367. Epub 2023 Feb 28 doi: 10.1097/FTD.0000000000001080. PMID: 36863027
Severe HIV-1 encephalitis and development of cerebral non-Hodgkin lymphoma in a patient with persistent strong HIV-1 replication in the brain despite potent HAART -- case report and review of the literature.
Baeuerle M, Schmitt-Haendle M, Taubald A, Mueller S, Walter H, Pfeiffer C, Manger B, Harrer T
Eur J Med Res 2005 Jul 29;10(7):309-16. PMID: 16055403
A medical research council randomized trial in patients with primary cerebral non-Hodgkin lymphoma: cerebral radiotherapy with and without cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy.
Mead GM, Bleehen NM, Gregor A, Bullimore J, Shirley D, Rampling RP, Trevor J, Glaser MG, Lantos P, Ironside JW, Moss TH, Brada M, Whaley JB, Stenning SP
Cancer 2000 Sep 15;89(6):1359-70. PMID: 11002232

Prognosis

Severe HIV-1 encephalitis and development of cerebral non-Hodgkin lymphoma in a patient with persistent strong HIV-1 replication in the brain despite potent HAART -- case report and review of the literature.
Baeuerle M, Schmitt-Haendle M, Taubald A, Mueller S, Walter H, Pfeiffer C, Manger B, Harrer T
Eur J Med Res 2005 Jul 29;10(7):309-16. PMID: 16055403
A medical research council randomized trial in patients with primary cerebral non-Hodgkin lymphoma: cerebral radiotherapy with and without cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy.
Mead GM, Bleehen NM, Gregor A, Bullimore J, Shirley D, Rampling RP, Trevor J, Glaser MG, Lantos P, Ironside JW, Moss TH, Brada M, Whaley JB, Stenning SP
Cancer 2000 Sep 15;89(6):1359-70. PMID: 11002232
Primary cerebral anaplastic T-cell-lymphoma (type Ki-1): review and case report.
Feldges A, Gerhard L, Reinhardt V, Budach V
Clin Neuropathol 1992 Mar-Apr;11(2):55-9. PMID: 1318814

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