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External ear basal cell carcinoma

MedGen UID:
234239
•Concept ID:
C1333491
•
Neoplastic Process
Synonyms: Basal Cell Carcinoma of External Ear; basal cell carcinoma of external Ear; basal cell carcinoma of external ear; Basal Cell Carcinoma of the External Ear; basal cell carcinoma of the external Ear; basal cell carcinoma of the external ear; basal cell external ear carcinoma; External Ear Basal Cell Carcinoma; external ear basal cell carcinoma; external Ear basal cell carcinoma; external ear skin basal cell carcinoma; skin basal cell carcinoma of external ear
 
Monarch Initiative: MONDO:0002943

Definition

A basal cell carcinoma that arises from the skin of the external ear. [from NCI]

Professional guidelines

PubMed

Carcinoma of the external auditory canal: histological and treatment groups.
Hosokawa S, Mizuta K, Takahashi G, Okamura J, Takizawa Y, Hosokawa K, Yamatodani T, Mineta H
B-ENT 2014;10(4):259-64. PMID: 25654948
Melanotic and non-melanotic malignancies of the face and external ear - A review of current treatment concepts and future options.
Kolk A, Wolff KD, Smeets R, Kesting M, Hein R, Eckert AW
Cancer Treat Rev 2014 Aug;40(7):819-37. Epub 2014 Apr 16 doi: 10.1016/j.ctrv.2014.04.002. PMID: 24814015
Optimum management of the discharging ear.
Ruddy J, Bickerton RC
Drugs 1992 Feb;43(2):219-35. doi: 10.2165/00003495-199243020-00008. PMID: 1372220

Recent clinical studies

Etiology

Malignant lesions of the ear.
Tammaro A, Adebanjo GAR, Chello C, Parisella FR, Cantisani C, Farnetani F, Pellacani G
Arch Dermatol Res 2022 Nov;314(9):839-845. Epub 2021 Nov 18 doi: 10.1007/s00403-021-02304-0. PMID: 34792642
External auditory canal carcinoma: clinical characteristics and long-term treatment outcomes.
Correia-Rodrigues P, Ramalho S, Montalvão P, Magalhães M
Eur Arch Otorhinolaryngol 2020 Oct;277(10):2709-2720. Epub 2020 May 4 doi: 10.1007/s00405-020-06019-2. PMID: 32367152
Temporal bone carcinoma: Treatment patterns and survival.
Seligman KL, Sun DQ, Ten Eyck PP, Schularick NM, Hansen MR
Laryngoscope 2020 Jan;130(1):E11-E20. Epub 2019 Mar 15 doi: 10.1002/lary.27877. PMID: 30874314Free PMC Article
Basal cell carcinoma of the temporal bone and external auditory canal.
Breen JT, Roberts DB, Gidley PW
Laryngoscope 2018 Jun;128(6):1425-1430. Epub 2017 Aug 29 doi: 10.1002/lary.26785. PMID: 28850700
Dermatologic diseases of the external ear.
Oztürkcan S, Oztürkcan S
Clin Dermatol 2014 Jan-Feb;32(1):141-52. doi: 10.1016/j.clindermatol.2013.05.036. PMID: 24314388

Diagnosis

Malignant lesions of the ear.
Tammaro A, Adebanjo GAR, Chello C, Parisella FR, Cantisani C, Farnetani F, Pellacani G
Arch Dermatol Res 2022 Nov;314(9):839-845. Epub 2021 Nov 18 doi: 10.1007/s00403-021-02304-0. PMID: 34792642
Locally aggressive trichilemmal carcinoma.
Maya-Rico AM, Jaramillo-Pulgarín C, Londoño-García Á, Peña-Zúñiga B
An Bras Dermatol 2018 Jul-Aug;93(4):579-581. doi: 10.1590/abd1806-4841.20187461. PMID: 30066770Free PMC Article
Melanotic and non-melanotic malignancies of the face and external ear - A review of current treatment concepts and future options.
Kolk A, Wolff KD, Smeets R, Kesting M, Hein R, Eckert AW
Cancer Treat Rev 2014 Aug;40(7):819-37. Epub 2014 Apr 16 doi: 10.1016/j.ctrv.2014.04.002. PMID: 24814015
Dermatologic diseases of the external ear.
Oztürkcan S, Oztürkcan S
Clin Dermatol 2014 Jan-Feb;32(1):141-52. doi: 10.1016/j.clindermatol.2013.05.036. PMID: 24314388
Epidemiology of basal cell carcinoma and squamous cell carcinoma of the pinna.
Ahmad I, Das Gupta AR
J Laryngol Otol 2001 Feb;115(2):85-6. doi: 10.1258/0022215011907497. PMID: 11320842

Therapy

Salvage re-irradiation in non-melanoma skin cancers: A multicenter analysis.
Miszczyk M, Suleja A, Sobel S, Stec M, Chyrek AJ, Kolbusz M, Spałek M, Nasiek A, Stankiewicz M, Lelek P, Moll M, Kluska A, Kazalski D, Saniewski P, Kaminiów K, Burchardt WM, Wojcieszek P, Chicheł A, Cichoń P, Krzysztofiak T
Radiother Oncol 2023 Dec;189:109945. Epub 2023 Oct 6 doi: 10.1016/j.radonc.2023.109945. PMID: 37806558
Rate and Proportion of Malignant Skin Biopsies for Basal Cell and Squamous Cell Carcinoma on the Face and Ears After a Single Course of Topical 5-Fluorouracil: The Veterans Affairs Keratinocyte Carcinoma Chemoprevention Trial.
Means AD, Leader NF, Siegel JA, Arron ST, Walker JL, Pomerantz H, Beatson M, Weinstock MA
Dermatol Surg 2021 Apr 1;47(4):541-543. doi: 10.1097/DSS.0000000000002437. PMID: 33795573
Repair of a Deep Auricular Wound.
Potter KA, Charos AE, Chen DL
Dermatol Surg 2020 Dec;46(12):1737-1739. doi: 10.1097/DSS.0000000000002197. PMID: 31592919
Photodynamic therapy for basal cell carcinoma of external auditory canal: A case report.
Xu S, Zhang L, Zhang M
Photodiagnosis Photodyn Ther 2019 Dec;28:102-104. Epub 2019 Aug 6 doi: 10.1016/j.pdpdt.2019.08.008. PMID: 31398513
Basal cell carcinoma of the earlobe after auricular acupuncture.
Brouard M, Kaya G, Vecchietti G, Chavaz P, Harms M
Dermatology 2002;204(2):142-4. doi: 10.1159/000051834. PMID: 11937742

Prognosis

miR-34a predicts the prognosis of advanced-stage external auditory canal squamous cell carcinoma.
Akiyama N, Yamamoto-Fukuda T, Kojima H
Acta Otolaryngol 2022 Jun;142(6):537-541. Epub 2022 Jun 22 doi: 10.1080/00016489.2022.2086292. PMID: 35732008
Malignant lesions of the ear.
Tammaro A, Adebanjo GAR, Chello C, Parisella FR, Cantisani C, Farnetani F, Pellacani G
Arch Dermatol Res 2022 Nov;314(9):839-845. Epub 2021 Nov 18 doi: 10.1007/s00403-021-02304-0. PMID: 34792642
External auditory canal carcinoma: clinical characteristics and long-term treatment outcomes.
Correia-Rodrigues P, Ramalho S, Montalvão P, Magalhães M
Eur Arch Otorhinolaryngol 2020 Oct;277(10):2709-2720. Epub 2020 May 4 doi: 10.1007/s00405-020-06019-2. PMID: 32367152
Temporal bone carcinoma: Treatment patterns and survival.
Seligman KL, Sun DQ, Ten Eyck PP, Schularick NM, Hansen MR
Laryngoscope 2020 Jan;130(1):E11-E20. Epub 2019 Mar 15 doi: 10.1002/lary.27877. PMID: 30874314Free PMC Article
Basal cell carcinoma of the temporal bone and external auditory canal.
Breen JT, Roberts DB, Gidley PW
Laryngoscope 2018 Jun;128(6):1425-1430. Epub 2017 Aug 29 doi: 10.1002/lary.26785. PMID: 28850700

Clinical prediction guides

miR-34a predicts the prognosis of advanced-stage external auditory canal squamous cell carcinoma.
Akiyama N, Yamamoto-Fukuda T, Kojima H
Acta Otolaryngol 2022 Jun;142(6):537-541. Epub 2022 Jun 22 doi: 10.1080/00016489.2022.2086292. PMID: 35732008
VITOM-3D assisted paramedian forehead flap for nasal reconstruction.
Achena A, Placentino A, Mevio N, Pilolli F, Roncoroni L, Borin M, Mantini G, Ormellese GL, Dragonetti AG
Am J Otolaryngol 2022 Sep-Oct;43(5):103493. Epub 2022 May 10 doi: 10.1016/j.amjoto.2022.103493. PMID: 35715292
External auditory canal carcinoma: clinical characteristics and long-term treatment outcomes.
Correia-Rodrigues P, Ramalho S, Montalvão P, Magalhães M
Eur Arch Otorhinolaryngol 2020 Oct;277(10):2709-2720. Epub 2020 May 4 doi: 10.1007/s00405-020-06019-2. PMID: 32367152
Temporal bone carcinoma: Treatment patterns and survival.
Seligman KL, Sun DQ, Ten Eyck PP, Schularick NM, Hansen MR
Laryngoscope 2020 Jan;130(1):E11-E20. Epub 2019 Mar 15 doi: 10.1002/lary.27877. PMID: 30874314Free PMC Article
Clinical analysis of seborrheic keratoses in the ear: a retrospective study and literature review.
Kim KW, Chang J, Lee S, Im GJ, Chae SW, Jung HH, Choi J
Eur Arch Otorhinolaryngol 2015 May;272(5):1113-7. Epub 2014 Feb 11 doi: 10.1007/s00405-014-2921-x. PMID: 24515921

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