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Paranasal Sinus Diffuse Large B-Cell Lymphoma

MedGen UID:
235460
•Concept ID:
C1335338
•
Neoplastic Process
Synonyms: Accessory Sinus Diffuse Large B-Cell Lymphoma; Diffuse Large B-Cell Lymphoma of Accessory Sinus; Diffuse Large B-Cell Lymphoma of Paranasal Sinus; Diffuse Large B-Cell Lymphoma of the Accessory Sinus; Diffuse Large B-Cell Lymphoma of the Paranasal Sinus; Primary Paranasal Sinus Diffuse Large B-Cell Lymphoma

Definition

A non-Hodgkin lymphoma that arises from the paranasal sinus and is characterized by the presence of a diffuse malignant infiltrate composed of large B-lymphocytes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParanasal Sinus Diffuse Large B-Cell Lymphoma

Professional guidelines

PubMed

Primary sinonasal lymphoma: A multi-institutional experience of clinical presentation, treatment, and outcomes.
Eide JG, Kshirsagar RS, Birkenbeuel JL, Abello EH, Hobday S, Herzberg S, Wang BY, Palmer JN, Adappa ND, Kuan EC
Int Forum Allergy Rhinol 2023 Aug;13(8):1492-1502. Epub 2022 Dec 7 doi: 10.1002/alr.23102. PMID: 36433723
Treatment Modalities and Survival Outcomes for Sinonasal Diffuse Large B-Cell Lymphoma.
Lehrich BM, Abiri A, Goshtasbi K, Birkenbeuel J, Yasaka TM, Papagiannopoulos P, Tajudeen BA, Brem EA, Kuan EC
Laryngoscope 2021 Nov;131(11):E2727-E2735. Epub 2021 Apr 26 doi: 10.1002/lary.29584. PMID: 33899946Free PMC Article
Epidemiologic, prognostic, and treatment factors in sinonasal diffuse large B -cell lymphoma.
Varelas AN, Eggerstedt M, Ganti A, Tajudeen BA
Laryngoscope 2019 Jun;129(6):1259-1264. Epub 2018 Dec 20 doi: 10.1002/lary.27639. PMID: 30570148

Recent clinical studies

Etiology

Clinical characteristics analysis of sinonasal diffuse large B-cell lymphoma and extranodal NK/T-cell lymphoma.
Jang HB, Lee DH, Song GY, Yang DH, Lim SC
Int Forum Allergy Rhinol 2023 Dec;13(12):2256-2258. Epub 2023 Jul 1 doi: 10.1002/alr.23217. PMID: 37329243
Sinonasal B-cell lymphomas: A nationwide cohort study, with an emphasis on the prognosis and the recurrence pattern of primary diffuse large B-cell lymphoma.
Eriksen PRG, Clasen-Linde E, Nully Brown P, Haunstrup L, Christoffersen M, Asdahl P, Thomsen TM, Harwood CD, Heegaard S, Buchwald CV
Hematol Oncol 2022 Apr;40(2):160-171. Epub 2022 Feb 6 doi: 10.1002/hon.2968. PMID: 35104916Free PMC Article
Treatment Modalities and Survival Outcomes for Sinonasal Diffuse Large B-Cell Lymphoma.
Lehrich BM, Abiri A, Goshtasbi K, Birkenbeuel J, Yasaka TM, Papagiannopoulos P, Tajudeen BA, Brem EA, Kuan EC
Laryngoscope 2021 Nov;131(11):E2727-E2735. Epub 2021 Apr 26 doi: 10.1002/lary.29584. PMID: 33899946Free PMC Article
Epidemiologic, prognostic, and treatment factors in sinonasal diffuse large B -cell lymphoma.
Varelas AN, Eggerstedt M, Ganti A, Tajudeen BA
Laryngoscope 2019 Jun;129(6):1259-1264. Epub 2018 Dec 20 doi: 10.1002/lary.27639. PMID: 30570148
Lymphoma of the nasal cavity and paranasal sinuses: A case series.
Steele TO, Buniel MC, Mace JC, El Rassi E, Smith TL
Am J Rhinol Allergy 2016 Sep;30(5):335-9. doi: 10.2500/ajra.2016.30.4347. PMID: 27657899

Diagnosis

Clinical characteristics analysis of sinonasal diffuse large B-cell lymphoma and extranodal NK/T-cell lymphoma.
Jang HB, Lee DH, Song GY, Yang DH, Lim SC
Int Forum Allergy Rhinol 2023 Dec;13(12):2256-2258. Epub 2023 Jul 1 doi: 10.1002/alr.23217. PMID: 37329243
Treatment Modalities and Survival Outcomes for Sinonasal Diffuse Large B-Cell Lymphoma.
Lehrich BM, Abiri A, Goshtasbi K, Birkenbeuel J, Yasaka TM, Papagiannopoulos P, Tajudeen BA, Brem EA, Kuan EC
Laryngoscope 2021 Nov;131(11):E2727-E2735. Epub 2021 Apr 26 doi: 10.1002/lary.29584. PMID: 33899946Free PMC Article
Pediatric Diffuse Large B-Cell Lymphoma of the Frontal Sinus: A Case Report.
Knudson SA, Day KM, Harshbarger RJ
Cleft Palate Craniofac J 2019 Sep;56(8):1089-1095. Epub 2019 Mar 5 doi: 10.1177/1055665619831165. PMID: 30836788
Primary diffuse large B-cell lymphoma of the frontal sinus.
Yang JP, Hu CM, Zhong W, Wang ZG
J Biol Regul Homeost Agents 2017 Apr-Jun;31(2):447-451. PMID: 28685551
Hematolymphoid lesions of the sinonasal tract.
Crane GM, Duffield AS
Semin Diagn Pathol 2016 Mar;33(2):71-80. Epub 2015 Sep 9 doi: 10.1053/j.semdp.2015.09.008. PMID: 26472692Free PMC Article

Therapy

Sinonasal B-cell lymphomas: A nationwide cohort study, with an emphasis on the prognosis and the recurrence pattern of primary diffuse large B-cell lymphoma.
Eriksen PRG, Clasen-Linde E, Nully Brown P, Haunstrup L, Christoffersen M, Asdahl P, Thomsen TM, Harwood CD, Heegaard S, Buchwald CV
Hematol Oncol 2022 Apr;40(2):160-171. Epub 2022 Feb 6 doi: 10.1002/hon.2968. PMID: 35104916Free PMC Article
Treatment Modalities and Survival Outcomes for Sinonasal Diffuse Large B-Cell Lymphoma.
Lehrich BM, Abiri A, Goshtasbi K, Birkenbeuel J, Yasaka TM, Papagiannopoulos P, Tajudeen BA, Brem EA, Kuan EC
Laryngoscope 2021 Nov;131(11):E2727-E2735. Epub 2021 Apr 26 doi: 10.1002/lary.29584. PMID: 33899946Free PMC Article
Lymphoma of the nasal cavity and paranasal sinuses: A case series.
Steele TO, Buniel MC, Mace JC, El Rassi E, Smith TL
Am J Rhinol Allergy 2016 Sep;30(5):335-9. doi: 10.2500/ajra.2016.30.4347. PMID: 27657899
Antibiotic-refractory sinusitis.
Munoz J, Kuriakose P
JAMA 2012 Dec 12;308(22):2399-400. doi: 10.1001/jama.2012.91077. PMID: 23232896
Primary diffuse large B-cell lymphoma of the ethmoid sinus.
Terada T
Int J Clin Exp Pathol 2011;4(8):799-801. Epub 2011 Nov 3 PMID: 22135730Free PMC Article

Prognosis

Clinical characteristics analysis of sinonasal diffuse large B-cell lymphoma and extranodal NK/T-cell lymphoma.
Jang HB, Lee DH, Song GY, Yang DH, Lim SC
Int Forum Allergy Rhinol 2023 Dec;13(12):2256-2258. Epub 2023 Jul 1 doi: 10.1002/alr.23217. PMID: 37329243
Diffuse Large B-Cell Lymphoma 18 Years After Bilateral Lacrimal Gland IgG4-Related Disease: Case Report and Literature Review.
Matsuo T, Tanaka T, Notohara K, Okada K
J Investig Med High Impact Case Rep 2022 Jan-Dec;10:23247096211067894. doi: 10.1177/23247096211067894. PMID: 35038946Free PMC Article
Treatment Modalities and Survival Outcomes for Sinonasal Diffuse Large B-Cell Lymphoma.
Lehrich BM, Abiri A, Goshtasbi K, Birkenbeuel J, Yasaka TM, Papagiannopoulos P, Tajudeen BA, Brem EA, Kuan EC
Laryngoscope 2021 Nov;131(11):E2727-E2735. Epub 2021 Apr 26 doi: 10.1002/lary.29584. PMID: 33899946Free PMC Article
Epidemiologic, prognostic, and treatment factors in sinonasal diffuse large B -cell lymphoma.
Varelas AN, Eggerstedt M, Ganti A, Tajudeen BA
Laryngoscope 2019 Jun;129(6):1259-1264. Epub 2018 Dec 20 doi: 10.1002/lary.27639. PMID: 30570148
Hematolymphoid lesions of the sinonasal tract.
Crane GM, Duffield AS
Semin Diagn Pathol 2016 Mar;33(2):71-80. Epub 2015 Sep 9 doi: 10.1053/j.semdp.2015.09.008. PMID: 26472692Free PMC Article

Clinical prediction guides

Primary sinonasal lymphoma: A multi-institutional experience of clinical presentation, treatment, and outcomes.
Eide JG, Kshirsagar RS, Birkenbeuel JL, Abello EH, Hobday S, Herzberg S, Wang BY, Palmer JN, Adappa ND, Kuan EC
Int Forum Allergy Rhinol 2023 Aug;13(8):1492-1502. Epub 2022 Dec 7 doi: 10.1002/alr.23102. PMID: 36433723
Treatment Modalities and Survival Outcomes for Sinonasal Diffuse Large B-Cell Lymphoma.
Lehrich BM, Abiri A, Goshtasbi K, Birkenbeuel J, Yasaka TM, Papagiannopoulos P, Tajudeen BA, Brem EA, Kuan EC
Laryngoscope 2021 Nov;131(11):E2727-E2735. Epub 2021 Apr 26 doi: 10.1002/lary.29584. PMID: 33899946Free PMC Article
Fatal primary diffuse large B-cell lymphoma of the maxillary sinus initially treated as an infectious disease in an elderly patient: A clinicopathologic report.
de Castro MS, Ribeiro CM, de Carli ML, Pereira AAC, Sperandio FF, de Almeida OP, Hanemann JAC
Gerodontology 2018 Mar;35(1):59-62. doi: 10.1111/ger.12308. PMID: 29392788
MRI of diffuse large B-cell non-Hodgkin's lymphoma of the head and neck: comparison of Waldeyer's ring and sinonasal lymphoma.
King AD, Law BK, Tang WK, Mo FK, Raghupathy R, Bhatia KS, Lei KI
Eur Arch Otorhinolaryngol 2017 Feb;274(2):1079-1087. Epub 2016 Oct 13 doi: 10.1007/s00405-016-4337-2. PMID: 27738821
Primary diffuse large B-cell non-Hodgkin lymphoma of the paranasal sinuses: a report of 14 cases.
Oprea C, Cainap C, Azoulay R, Assaf E, Jabbour E, Koscielny S, Lapusan S, Vanel D, Bosq J, Ribrag V
Br J Haematol 2005 Nov;131(4):468-71. doi: 10.1111/j.1365-2141.2005.05787.x. PMID: 16281936

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