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Sclerosing adenosis of breast

MedGen UID:
235582
•Concept ID:
C1335931
•
Disease or Syndrome
Synonyms: Breast Sclerosing Adenosis; breast sclerosing adenosis; sclerosing adenosis; Sclerosing Adenosis of Breast; sclerosing adenosis of breast; Sclerosing Adenosis of the Breast; sclerosing adenosis of the breast; Sclerosing Breast Adenosis; sclerosing breast adenosis
SNOMED CT: Sclerosing adenosis of breast (105261000119101)
 
Monarch Initiative: MONDO:0004531

Definition

Breast adenosis characterized by the proliferation of acini, a lobulated architectural pattern, and stromal sclerosis. The luminal epithelial and myopepithelial cells are preserved. Microcalcifications and foci of apocrine metaplasia may be present. [from NCI]

Professional guidelines

PubMed

Core needle biopsy of benign, borderline and in-situ problematic lesions of the breast: Diagnosis, differential diagnosis and immunohistochemistry.
Rosa M, Agosto-Arroyo E
Ann Diagn Pathol 2019 Dec;43:151407. Epub 2019 Sep 3 doi: 10.1016/j.anndiagpath.2019.151407. PMID: 31634810
The diagnosis and management of diabetic mastopathy.
Thorncroft K, Forsyth L, Desmond S, Audisio RA
Breast J 2007 Nov-Dec;13(6):607-13. doi: 10.1111/j.1524-4741.2007.00489.x. PMID: 17983405
Breast disease: a primer on diagnosis and management.
Drukker BH
Int J Fertil Womens Med 1997 Sep-Oct;42(5):278-87. PMID: 9406832

Recent clinical studies

Etiology

Deep learning radiomics of ultrasonography for differentiating sclerosing adenosis from breast cancer.
Li C, Zhang H, Chen J, Shao S, Li X, Yao M, Zheng Y, Wu R, Shi J
Clin Hemorheol Microcirc 2023;84(2):153-163. doi: 10.3233/CH-221608. PMID: 36373313
Conventional and contrast-enhanced ultrasound features in sclerosing adenosis and correlation with pathology.
Shao S, Yao M, Li X, Li C, Chen J, Li G, Jia C, Wu R
Clin Hemorheol Microcirc 2021;77(2):173-181. doi: 10.3233/CH-200943. PMID: 32924999
Ultrasound characteristics of sclerosing adenosis mimicking breast carcinoma.
Liu W, Li W, Li Z, Shi L, Zhao P, Guo Z, Tian J, Wang Z
Breast Cancer Res Treat 2020 May;181(1):127-134. Epub 2020 Mar 29 doi: 10.1007/s10549-020-05609-2. PMID: 32227257
Radiological and clinical findings in sclerosing adenosis of the breast.
Tan H, Zhang H, Lei Z, Fu F, Wang M
Medicine (Baltimore) 2019 Sep;98(39):e17061. doi: 10.1097/MD.0000000000017061. PMID: 31574804Free PMC Article
Sclerosing adenosis and risk of breast cancer.
Visscher DW, Nassar A, Degnim AC, Frost MH, Vierkant RA, Frank RD, Tarabishy Y, Radisky DC, Hartmann LC
Breast Cancer Res Treat 2014 Feb;144(1):205-12. Epub 2014 Feb 8 doi: 10.1007/s10549-014-2862-5. PMID: 24510013Free PMC Article

Diagnosis

Apocrine lesions of the breast.
Quinn CM, D'Arcy C, Wells C
Virchows Arch 2022 Jan;480(1):177-189. Epub 2021 Sep 18 doi: 10.1007/s00428-021-03185-4. PMID: 34537861Free PMC Article
Sclerosing Polycystic Adenoma.
Bishop JA, Thompson LDR
Surg Pathol Clin 2021 Mar;14(1):17-24. doi: 10.1016/j.path.2020.09.004. PMID: 33526220
Ultrasound characteristics of sclerosing adenosis mimicking breast carcinoma.
Liu W, Li W, Li Z, Shi L, Zhao P, Guo Z, Tian J, Wang Z
Breast Cancer Res Treat 2020 May;181(1):127-134. Epub 2020 Mar 29 doi: 10.1007/s10549-020-05609-2. PMID: 32227257
Benign mimickers of malignant breast lesions.
Spruill L
Semin Diagn Pathol 2016 Jan;33(1):2-12. Epub 2015 Sep 5 doi: 10.1053/j.semdp.2015.09.002. PMID: 26472694
Sclerosing adenosis.
Preece PE
World J Surg 1989 Nov-Dec;13(6):721-5. doi: 10.1007/BF01658421. PMID: 2623882

Therapy

Conventional and contrast-enhanced ultrasound features in sclerosing adenosis and correlation with pathology.
Shao S, Yao M, Li X, Li C, Chen J, Li G, Jia C, Wu R
Clin Hemorheol Microcirc 2021;77(2):173-181. doi: 10.3233/CH-200943. PMID: 32924999
Computer-assisted Diagnosis of Breast Cancer by Cell Network Matrix Extraction and Multilayer Perceptron Analysis.
Boroujeni AM, Yousefi E, Haseeb MA, Gupta R
Ann Clin Lab Sci 2020 Mar;50(2):175-181. PMID: 32366554
IgG4-related sclerosing disease of the breast successfully treated by steroid therapy.
Ogiya A, Tanaka K, Tadokoro Y, Kikutani M, Uematsu T, Kashiwagi H, Kasami M, Takahashi K
Breast Cancer 2014 Mar;21(2):231-5. Epub 2010 Nov 3 doi: 10.1007/s12282-010-0225-6. PMID: 21042890
Epstein-Barr virus and breast cancer: lack of evidence for an association in Iranian women.
Kadivar M, Monabati A, Joulaee A, Hosseini N
Pathol Oncol Res 2011 Sep;17(3):489-92. Epub 2011 Jan 6 doi: 10.1007/s12253-010-9325-z. PMID: 21207256
Hormone replacement therapy and the risk of breast lesions that predispose to cancer.
Cahn MD, Tran T, Theur CP, Butler JA
Am Surg 1997 Oct;63(10):858-60. PMID: 9322657

Prognosis

Deep learning radiomics of ultrasonography for differentiating sclerosing adenosis from breast cancer.
Li C, Zhang H, Chen J, Shao S, Li X, Yao M, Zheng Y, Wu R, Shi J
Clin Hemorheol Microcirc 2023;84(2):153-163. doi: 10.3233/CH-221608. PMID: 36373313
Sclerosing Polycystic Adenoma.
Bishop JA, Thompson LDR
Surg Pathol Clin 2021 Mar;14(1):17-24. doi: 10.1016/j.path.2020.09.004. PMID: 33526220
Ultrasound characteristics of sclerosing adenosis mimicking breast carcinoma.
Liu W, Li W, Li Z, Shi L, Zhao P, Guo Z, Tian J, Wang Z
Breast Cancer Res Treat 2020 May;181(1):127-134. Epub 2020 Mar 29 doi: 10.1007/s10549-020-05609-2. PMID: 32227257
Breast carcinoma in sclerosing adenosis: a clinicopathological and immunophenotypical analysis on 206 lesions.
Yu BH, Tang SX, Xu XL, Cheng YF, Bi R, Shui RH, Tu XY, Lu HF, Zhou XY, Yang WT
J Clin Pathol 2018 Jun;71(6):546-553. Epub 2018 Feb 7 doi: 10.1136/jclinpath-2017-204751. PMID: 29436376
Sclerosing adenosis and risk of breast cancer.
Visscher DW, Nassar A, Degnim AC, Frost MH, Vierkant RA, Frank RD, Tarabishy Y, Radisky DC, Hartmann LC
Breast Cancer Res Treat 2014 Feb;144(1):205-12. Epub 2014 Feb 8 doi: 10.1007/s10549-014-2862-5. PMID: 24510013Free PMC Article

Clinical prediction guides

Deep learning radiomics of ultrasonography for differentiating sclerosing adenosis from breast cancer.
Li C, Zhang H, Chen J, Shao S, Li X, Yao M, Zheng Y, Wu R, Shi J
Clin Hemorheol Microcirc 2023;84(2):153-163. doi: 10.3233/CH-221608. PMID: 36373313
Ultrasound characteristics of sclerosing adenosis mimicking breast carcinoma.
Liu W, Li W, Li Z, Shi L, Zhao P, Guo Z, Tian J, Wang Z
Breast Cancer Res Treat 2020 May;181(1):127-134. Epub 2020 Mar 29 doi: 10.1007/s10549-020-05609-2. PMID: 32227257
Breast carcinoma in sclerosing adenosis: a clinicopathological and immunophenotypical analysis on 206 lesions.
Yu BH, Tang SX, Xu XL, Cheng YF, Bi R, Shui RH, Tu XY, Lu HF, Zhou XY, Yang WT
J Clin Pathol 2018 Jun;71(6):546-553. Epub 2018 Feb 7 doi: 10.1136/jclinpath-2017-204751. PMID: 29436376
NanoString-based breast cancer risk prediction for women with sclerosing adenosis.
Winham SJ, Mehner C, Heinzen EP, Broderick BT, Stallings-Mann M, Nassar A, Vierkant RA, Hoskin TL, Frank RD, Wang C, Denison LA, Vachon CM, Frost MH, Hartmann LC, Aubrey Thompson E, Sherman ME, Visscher DW, Degnim AC, Radisky DC
Breast Cancer Res Treat 2017 Nov;166(2):641-650. Epub 2017 Aug 10 doi: 10.1007/s10549-017-4441-z. PMID: 28798985Free PMC Article
Sclerosing adenosis and risk of breast cancer.
Visscher DW, Nassar A, Degnim AC, Frost MH, Vierkant RA, Frank RD, Tarabishy Y, Radisky DC, Hartmann LC
Breast Cancer Res Treat 2014 Feb;144(1):205-12. Epub 2014 Feb 8 doi: 10.1007/s10549-014-2862-5. PMID: 24510013Free PMC Article

Recent systematic reviews

Adenosquamous proliferation in radial sclerosing lesions: Histologic spectrum and key features in systematic review of 247 lesions.
Bachert SE, Cornea V, Bocklage T
Breast 2023 Oct;71:99-105. Epub 2023 Aug 7 doi: 10.1016/j.breast.2023.08.002. PMID: 37566996Free PMC Article

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