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Signet ring cell breast carcinoma

MedGen UID:
236816
•Concept ID:
C1335964
•
Neoplastic Process
Synonyms: breast carcinoma with signet ring; breast signet ring cell adenocarcinoma; Breast Signet Ring Cell Carcinoma; breast signet ring cell carcinoma; Breast Signet-Ring Cell Carcinoma; Mammary Signet Ring Cell Carcinoma; mammary signet Ring cell carcinoma; Primary Mammary Signet Ring Cell Carcinoma; primary mammary signet Ring cell carcinoma; Primary Signet Ring Cell Breast Carcinoma; primary signet Ring cell breast carcinoma; Primary Signet Ring Cell Carcinoma of Breast; primary signet Ring cell carcinoma of breast; Primary Signet Ring Cell Carcinoma of the Breast; primary signet Ring cell carcinoma of the breast; Primary SRC Breast Carcinoma; primary SRC breast carcinoma; Primary SRC Carcinoma of Breast; primary SRC carcinoma of breast; Primary SRC Carcinoma of the Breast; primary SRC carcinoma of the breast; Signet Ring Cell Breast Carcinoma; signet ring cell breast carcinoma; signet Ring cell breast carcinoma; Signet Ring Cell Carcinoma of Breast; signet Ring cell carcinoma of breast; signet ring cell carcinoma of breast; Signet Ring Cell Carcinoma of the Breast; signet Ring cell carcinoma of the breast; SRC Breast Carcinoma; SRC breast carcinoma; SRC Carcinoma of Breast; SRC carcinoma of breast; SRC Carcinoma of the Breast; SRC carcinoma of the breast
 
Monarch Initiative: MONDO:0002671

Definition

An invasive breast adenocarcinoma characterized by the presence of malignant epithelial cells with signet ring appearance. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSignet ring cell breast carcinoma

Professional guidelines

PubMed

Hereditary Diffuse Gastric Cancer: Approaches to Screening, Surveillance, and Treatment.
Pilonis ND, Tischkowitz M, Fitzgerald RC, di Pietro M
Annu Rev Med 2021 Jan 27;72:263-280. Epub 2020 Nov 20 doi: 10.1146/annurev-med-051019-103216. PMID: 33217247
Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers.
van der Post RS, Vogelaar IP, Carneiro F, Guilford P, Huntsman D, Hoogerbrugge N, Caldas C, Schreiber KE, Hardwick RH, Ausems MG, Bardram L, Benusiglio PR, Bisseling TM, Blair V, Bleiker E, Boussioutas A, Cats A, Coit D, DeGregorio L, Figueiredo J, Ford JM, Heijkoop E, Hermens R, Humar B, Kaurah P, Keller G, Lai J, Ligtenberg MJ, O'Donovan M, Oliveira C, Pinheiro H, Ragunath K, Rasenberg E, Richardson S, Roviello F, Schackert H, Seruca R, Taylor A, Ter Huurne A, Tischkowitz M, Joe ST, van Dijck B, van Grieken NC, van Hillegersberg R, van Sandick JW, Vehof R, van Krieken JH, Fitzgerald RC
J Med Genet 2015 Jun;52(6):361-74. Epub 2015 May 15 doi: 10.1136/jmedgenet-2015-103094. PMID: 25979631Free PMC Article
Hereditary diffuse gastric cancer: diagnosis and management.
Blair V, Martin I, Shaw D, Winship I, Kerr D, Arnold J, Harawira P, McLeod M, Parry S, Charlton A, Findlay M, Cox B, Humar B, More H, Guilford P
Clin Gastroenterol Hepatol 2006 Mar;4(3):262-75. doi: 10.1016/j.cgh.2005.12.003. PMID: 16527687

Recent clinical studies

Etiology

Prognostic Outcomes of Signet Ring Cell Carcinoma of the Breast.
Mehdi M, Kong AL, Frebault J, Huang S, Huang CC, Cortina CS
J Surg Res 2021 Aug;264:138-148. Epub 2021 Apr 3 doi: 10.1016/j.jss.2021.02.020. PMID: 33823490Free PMC Article

Diagnosis

Prognostic Outcomes of Signet Ring Cell Carcinoma of the Breast.
Mehdi M, Kong AL, Frebault J, Huang S, Huang CC, Cortina CS
J Surg Res 2021 Aug;264:138-148. Epub 2021 Apr 3 doi: 10.1016/j.jss.2021.02.020. PMID: 33823490Free PMC Article
Breast metastasis of gastric signet-ring cell carcinoma: a case report and literature review.
He CL, Chen P, Xia BL, Xiao Q, Cai FL
World J Surg Oncol 2015 Mar 26;13:120. doi: 10.1186/s12957-015-0538-1. PMID: 25890325Free PMC Article
Metastatic signet ring carcinoma of the breast as a source of positive cervicovaginal cytology. A case report.
Fiorella RM, Beckwith LG, Miller LK, Kragel PJ
Acta Cytol 1993 Nov-Dec;37(6):948-52. PMID: 8249518
Breast metastasis from gastric signet ring cell carcinoma, mimicking inflammatory carcinoma. A case report.
Cavazzini G, Colpani F, Cantore M, Aitini E, Rabbi C, Taffurelli M, Pari F, Bellomi A, Bertuzzi A, Smerierl F
Tumori 1993 Dec 31;79(6):450-3. doi: 10.1177/030089169307900617. PMID: 8171750

Therapy

Prognostic Outcomes of Signet Ring Cell Carcinoma of the Breast.
Mehdi M, Kong AL, Frebault J, Huang S, Huang CC, Cortina CS
J Surg Res 2021 Aug;264:138-148. Epub 2021 Apr 3 doi: 10.1016/j.jss.2021.02.020. PMID: 33823490Free PMC Article
Breast metastasis of gastric signet-ring cell carcinoma: a case report and literature review.
He CL, Chen P, Xia BL, Xiao Q, Cai FL
World J Surg Oncol 2015 Mar 26;13:120. doi: 10.1186/s12957-015-0538-1. PMID: 25890325Free PMC Article

Prognosis

Prognostic Outcomes of Signet Ring Cell Carcinoma of the Breast.
Mehdi M, Kong AL, Frebault J, Huang S, Huang CC, Cortina CS
J Surg Res 2021 Aug;264:138-148. Epub 2021 Apr 3 doi: 10.1016/j.jss.2021.02.020. PMID: 33823490Free PMC Article
Breast metastasis of gastric signet-ring cell carcinoma: a case report and literature review.
He CL, Chen P, Xia BL, Xiao Q, Cai FL
World J Surg Oncol 2015 Mar 26;13:120. doi: 10.1186/s12957-015-0538-1. PMID: 25890325Free PMC Article

Clinical prediction guides

Prognostic Outcomes of Signet Ring Cell Carcinoma of the Breast.
Mehdi M, Kong AL, Frebault J, Huang S, Huang CC, Cortina CS
J Surg Res 2021 Aug;264:138-148. Epub 2021 Apr 3 doi: 10.1016/j.jss.2021.02.020. PMID: 33823490Free PMC Article

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