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Splenic B Lymphoblastic Lymphoma

MedGen UID:
236844
•Concept ID:
C1336072
•
Neoplastic Process
Synonyms: Splenic B-Lymphoblastic Lymphoma; Splenic Precursor B-Lymphoblastic Lymphoma

Definition

B-lymphoblastic lymphoma that involves the spleen. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSplenic B Lymphoblastic Lymphoma

Professional guidelines

PubMed

Comparison of Myocyte Enhancer Factor 2B Versus Other Germinal Center-associated Antigens in the Differential Diagnosis of B-Cell Non-Hodgkin Lymphomas.
Moore EM, Swerdlow SH, Gibson SE
Am J Surg Pathol 2018 Mar;42(3):342-350. doi: 10.1097/PAS.0000000000001015. PMID: 29309299
Amphotericin B lipid complex for the treatment of patients with acute leukemia and hepatosplenic candidiasis.
Sallah S, Semelka RC, Sallah W, Vainright JR, Philips DL
Leuk Res 1999 Nov;23(11):995-9. doi: 10.1016/s0145-2126(99)00129-0. PMID: 10576503
Diagnosis and monitoring response to treatment of hepatosplenic candidiasis in patients with acute leukemia using magnetic resonance imaging.
Sallah S, Semelka R, Kelekis N, Worawattanakul S, Sallah W
Acta Haematol 1998;100(2):77-81. doi: 10.1159/000040869. PMID: 9792936

Recent clinical studies

Etiology

Shared genetic architecture between autoimmune disorders and B-cell acute lymphoblastic leukemia: insights from large-scale genome-wide cross-trait analysis.
Yu X, Chen Y, Chen J, Fan Y, Lu H, Wu D, Xu Y
BMC Med 2024 Apr 15;22(1):161. doi: 10.1186/s12916-024-03385-0. PMID: 38616254Free PMC Article
B-cell Non-Hodgkin Lymphomas with Plasmacytic Differentiation.
Harmon CM, Smith LB
Surg Pathol Clin 2016 Mar;9(1):11-28. doi: 10.1016/j.path.2015.09.007. PMID: 26940265
Targeting the B-cell receptor signaling pathway in B lymphoid malignancies.
Buchner M, Müschen M
Curr Opin Hematol 2014 Jul;21(4):341-9. doi: 10.1097/MOH.0000000000000048. PMID: 24811161Free PMC Article
Lymphoblastic lymphoma.
Cortelazzo S, Ponzoni M, Ferreri AJ, Hoelzer D
Crit Rev Oncol Hematol 2011 Sep;79(3):330-43. Epub 2011 Jan 26 doi: 10.1016/j.critrevonc.2010.12.003. PMID: 21273093
Nonnasal lymphoma expressing the natural killer cell marker CD56: a clinicopathologic study of 49 cases of an uncommon aggressive neoplasm.
Chan JK, Sin VC, Wong KF, Ng CS, Tsang WY, Chan CH, Cheung MM, Lau WH
Blood 1997 Jun 15;89(12):4501-13. PMID: 9192774

Diagnosis

Precursor B-ALL Cell Lines Differentially Respond to SYK Inhibition by Entospletinib.
Sender S, Sekora A, Villa Perez S, Chabanovska O, Becker A, Ngezahayo A, Junghanss C, Murua Escobar H
Int J Mol Sci 2021 Jan 8;22(2) doi: 10.3390/ijms22020592. PMID: 33435587Free PMC Article
Aggressive B-cell lymphomas with a primary bone marrow presentation.
Zamò A, Johnston P, Attygalle AD, Laurent C, Arber DA, Fend F
Histopathology 2020 Sep;77(3):369-379. Epub 2020 Jul 14 doi: 10.1111/his.14124. PMID: 32324290
B-cell Non-Hodgkin Lymphomas with Plasmacytic Differentiation.
Harmon CM, Smith LB
Surg Pathol Clin 2016 Mar;9(1):11-28. doi: 10.1016/j.path.2015.09.007. PMID: 26940265
Lymphoblastic lymphoma.
Cortelazzo S, Ponzoni M, Ferreri AJ, Hoelzer D
Crit Rev Oncol Hematol 2011 Sep;79(3):330-43. Epub 2011 Jan 26 doi: 10.1016/j.critrevonc.2010.12.003. PMID: 21273093
Lymphoblastic lymphoma with primary splenic involvement and the classic 14;18 translocation.
Carli MG, Cuneo A, Piva N, Balboni M, Fagioli F, Cavazzini P, Castoldi G
Cancer Genet Cytogenet 1991 Nov;57(1):47-51. doi: 10.1016/0165-4608(91)90188-z. PMID: 1756484

Therapy

Shared genetic architecture between autoimmune disorders and B-cell acute lymphoblastic leukemia: insights from large-scale genome-wide cross-trait analysis.
Yu X, Chen Y, Chen J, Fan Y, Lu H, Wu D, Xu Y
BMC Med 2024 Apr 15;22(1):161. doi: 10.1186/s12916-024-03385-0. PMID: 38616254Free PMC Article
An Anti-CD7 Antibody-Drug Conjugate Target Showing Potent Antitumor Activity for T-Lymphoblastic Leukemia (T-ALL).
Wang S, Zhang R, Zhong K, Guo W, Tong A
Biomolecules 2024 Jan 15;14(1) doi: 10.3390/biom14010106. PMID: 38254706Free PMC Article
Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma.
Mansouri L, Noerenberg D, Young E, Mylonas E, Abdulla M, Frick M, Asmar F, Ljungström V, Schneider M, Yoshida K, Skaftason A, Pandzic T, Gonzalez B, Tasidou A, Waldhueter N, Rivas-Delgado A, Angelopoulou M, Ziepert M, Arends CM, Couronné L, Lenze D, Baldus CD, Bastard C, Okosun J, Fitzgibbon J, Dörken B, Drexler HG, Roos-Weil D, Schmitt CA, Munch-Petersen HD, Zenz T, Hansmann ML, Strefford JC, Enblad G, Bernard OA, Ralfkiaer E, Erlanson M, Korkolopoulou P, Hultdin M, Papadaki T, Grønbæk K, Lopez-Guillermo A, Ogawa S, Küppers R, Stamatopoulos K, Stavroyianni N, Kanellis G, Rosenwald A, Campo E, Amini RM, Ott G, Vassilakopoulos TP, Hummel M, Rosenquist R, Damm F
Blood 2016 Dec 8;128(23):2666-2670. Epub 2016 Sep 26 doi: 10.1182/blood-2016-03-704528. PMID: 27670424
Interleukin-27 inhibits pediatric B-acute lymphoblastic leukemia cell spreading in a preclinical model.
Canale S, Cocco C, Frasson C, Seganfreddo E, Di Carlo E, Ognio E, Sorrentino C, Ribatti D, Zorzoli A, Basso G, Dufour C, Airoldi I
Leukemia 2011 Dec;25(12):1815-24. Epub 2011 Jun 24 doi: 10.1038/leu.2011.158. PMID: 21701492
Lymphoblastic lymphoma.
Cortelazzo S, Ponzoni M, Ferreri AJ, Hoelzer D
Crit Rev Oncol Hematol 2011 Sep;79(3):330-43. Epub 2011 Jan 26 doi: 10.1016/j.critrevonc.2010.12.003. PMID: 21273093

Prognosis

B-cell Non-Hodgkin Lymphomas with Plasmacytic Differentiation.
Harmon CM, Smith LB
Surg Pathol Clin 2016 Mar;9(1):11-28. doi: 10.1016/j.path.2015.09.007. PMID: 26940265
Targeting the B-cell receptor signaling pathway in B lymphoid malignancies.
Buchner M, Müschen M
Curr Opin Hematol 2014 Jul;21(4):341-9. doi: 10.1097/MOH.0000000000000048. PMID: 24811161Free PMC Article
Lymphoblastic lymphoma.
Cortelazzo S, Ponzoni M, Ferreri AJ, Hoelzer D
Crit Rev Oncol Hematol 2011 Sep;79(3):330-43. Epub 2011 Jan 26 doi: 10.1016/j.critrevonc.2010.12.003. PMID: 21273093
B-cell lymphoma of 708 cases in Japan: incidence rates and clinical prognosis according to the REAL classification.
Ohshima K, Suzumiya J, Sato K, Kanda M, Haraoka S, Kikuchi M
Cancer Lett 1999 Jan 8;135(1):73-81. doi: 10.1016/s0304-3835(98)00278-x. PMID: 10077224
Nonnasal lymphoma expressing the natural killer cell marker CD56: a clinicopathologic study of 49 cases of an uncommon aggressive neoplasm.
Chan JK, Sin VC, Wong KF, Ng CS, Tsang WY, Chan CH, Cheung MM, Lau WH
Blood 1997 Jun 15;89(12):4501-13. PMID: 9192774

Clinical prediction guides

Shared genetic architecture between autoimmune disorders and B-cell acute lymphoblastic leukemia: insights from large-scale genome-wide cross-trait analysis.
Yu X, Chen Y, Chen J, Fan Y, Lu H, Wu D, Xu Y
BMC Med 2024 Apr 15;22(1):161. doi: 10.1186/s12916-024-03385-0. PMID: 38616254Free PMC Article
Constitutively active CaMKII Drives B lineage acute lymphoblastic leukemia/lymphoma in tp53 mutant zebrafish.
Rothschild SC, Lai G, Tombes RM, Clements WK
PLoS Genet 2023 Dec;19(12):e1011102. Epub 2023 Dec 20 doi: 10.1371/journal.pgen.1011102. PMID: 38117861Free PMC Article
Combined Casein Kinase II inhibition and epigenetic modulation in acute B-lymphoblastic leukemia.
Richter A, Roolf C, Hamed M, Gladbach YS, Sender S, Konkolefski C, Knübel G, Sekora A, Fuellen G, Vollmar B, Murua Escobar H, Junghanss C
BMC Cancer 2019 Mar 6;19(1):202. doi: 10.1186/s12885-019-5411-0. PMID: 30841886Free PMC Article
Chronic TCDD exposure results in the dysregulation of gene expression in splenic B-lymphocytes and in the impairments in T-cell and B-cell differentiation in mouse model.
Feng Y, Tian J, Krylova I, Xu T, Xie HQ, Guo TL, Zhao B
J Environ Sci (China) 2016 Jan;39:218-227. Epub 2016 Jan 2 doi: 10.1016/j.jes.2015.11.011. PMID: 26899660
Targeting the B-cell receptor signaling pathway in B lymphoid malignancies.
Buchner M, Müschen M
Curr Opin Hematol 2014 Jul;21(4):341-9. doi: 10.1097/MOH.0000000000000048. PMID: 24811161Free PMC Article

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