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Non-Invasive Papillary Squamous Cell Carcinoma

MedGen UID:
266084
•Concept ID:
C1266003
•
Neoplastic Process
Synonyms: Papillary squamous cell carcinoma in situ; Papillary squamous cell carcinoma, non-invasive
SNOMED CT: Papillary squamous cell carcinoma in situ (128647004); Papillary squamous cell carcinoma, non-invasive (128647004)

Definition

A well differentiated squamous cell carcinoma characterized by a papillary, exophytic growth pattern, hyperkeratosis, and absence of invasion of adjacent tissues. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNon-Invasive Papillary Squamous Cell Carcinoma

Recent clinical studies

Etiology

Changes in the diagnosis of thyroid tumours in the 5th edition of the WHO classification of endocrine neoplasms.
J D
Cesk Patol 2024;60(1):59-63. PMID: 38697828
Diagnosis and therapy of actinic keratosis.
Thamm JR, Welzel J, Schuh S
J Dtsch Dermatol Ges 2024 May;22(5):675-690. Epub 2024 Mar 8 doi: 10.1111/ddg.15288. PMID: 38456369
Overview of the 2022 WHO Classification of Thyroid Neoplasms.
Baloch ZW, Asa SL, Barletta JA, Ghossein RA, Juhlin CC, Jung CK, LiVolsi VA, Papotti MG, Sobrinho-Simões M, Tallini G, Mete O
Endocr Pathol 2022 Mar;33(1):27-63. Epub 2022 Mar 14 doi: 10.1007/s12022-022-09707-3. PMID: 35288841
Utility of GATA-3 and Cytokeratin 5/6 Immunostains in Separating Condyloma Acuminatum Arising in the Urinary Tract From Non-Invasive Papillary Urothelial Carcinoma.
Montoya-Cerrillo D, Briski LM, Jorda M, Kryvenko ON
Int J Surg Pathol 2022 May;30(3):260-264. Epub 2021 Oct 19 doi: 10.1177/10668969211052235. PMID: 34665053
Urothelial eddies in papillary urothelial neoplasms: a distinct morphologic pattern with low risk for progression.
Kim M, Ro JY, Amin MB, de Peralta-Venturina M, Kwon GY, Park YW, Cho YM
Int J Clin Exp Pathol 2013;6(8):1458-66. Epub 2013 Jul 15 PMID: 23923064Free PMC Article

Diagnosis

Changes in the diagnosis of thyroid tumours in the 5th edition of the WHO classification of endocrine neoplasms.
J D
Cesk Patol 2024;60(1):59-63. PMID: 38697828
Diagnosis and therapy of actinic keratosis.
Thamm JR, Welzel J, Schuh S
J Dtsch Dermatol Ges 2024 May;22(5):675-690. Epub 2024 Mar 8 doi: 10.1111/ddg.15288. PMID: 38456369
Overview of the 2022 WHO Classification of Thyroid Neoplasms.
Baloch ZW, Asa SL, Barletta JA, Ghossein RA, Juhlin CC, Jung CK, LiVolsi VA, Papotti MG, Sobrinho-Simões M, Tallini G, Mete O
Endocr Pathol 2022 Mar;33(1):27-63. Epub 2022 Mar 14 doi: 10.1007/s12022-022-09707-3. PMID: 35288841
Utility of GATA-3 and Cytokeratin 5/6 Immunostains in Separating Condyloma Acuminatum Arising in the Urinary Tract From Non-Invasive Papillary Urothelial Carcinoma.
Montoya-Cerrillo D, Briski LM, Jorda M, Kryvenko ON
Int J Surg Pathol 2022 May;30(3):260-264. Epub 2021 Oct 19 doi: 10.1177/10668969211052235. PMID: 34665053
Immunohistochemical characterization of urothelial carcinoma.
Rajcani J, Kajo K, Adamkov M, Moravekova E, Lauko L, Felcanova D, Bencat M
Bratisl Lek Listy 2013;114(8):431-8. doi: 10.4149/bll_2013_091. PMID: 23944616

Prognosis

Overview of the 2022 WHO Classification of Thyroid Neoplasms.
Baloch ZW, Asa SL, Barletta JA, Ghossein RA, Juhlin CC, Jung CK, LiVolsi VA, Papotti MG, Sobrinho-Simões M, Tallini G, Mete O
Endocr Pathol 2022 Mar;33(1):27-63. Epub 2022 Mar 14 doi: 10.1007/s12022-022-09707-3. PMID: 35288841
Utility of GATA-3 and Cytokeratin 5/6 Immunostains in Separating Condyloma Acuminatum Arising in the Urinary Tract From Non-Invasive Papillary Urothelial Carcinoma.
Montoya-Cerrillo D, Briski LM, Jorda M, Kryvenko ON
Int J Surg Pathol 2022 May;30(3):260-264. Epub 2021 Oct 19 doi: 10.1177/10668969211052235. PMID: 34665053
Urothelial eddies in papillary urothelial neoplasms: a distinct morphologic pattern with low risk for progression.
Kim M, Ro JY, Amin MB, de Peralta-Venturina M, Kwon GY, Park YW, Cho YM
Int J Clin Exp Pathol 2013;6(8):1458-66. Epub 2013 Jul 15 PMID: 23923064Free PMC Article
Expression of cytokeratin 20 redefines urothelial papillomas of the bladder.
Harnden P, Mahmood N, Southgate J
Lancet 1999 Mar 20;353(9157):974-7. doi: 10.1016/S0140-6736(98)05383-5. PMID: 10459907
Verrucous acanthosis--so-called verrucous carcinoma--of the esophagus.
Barbier PA, Luder PJ, Wagner HE, Becker CD, Scheurer U, Ruchti C
Z Gastroenterol 1987 Feb;25(2):93-7. PMID: 3564599

Clinical prediction guides

Diagnosis and therapy of actinic keratosis.
Thamm JR, Welzel J, Schuh S
J Dtsch Dermatol Ges 2024 May;22(5):675-690. Epub 2024 Mar 8 doi: 10.1111/ddg.15288. PMID: 38456369
High prevalence of p16 staining in malignant tumors.
De Wispelaere N, Rico SD, Bauer M, Luebke AM, Kluth M, Büscheck F, Hube-Magg C, Höflmayer D, Gorbokon N, Weidemann S, Möller K, Fraune C, Bernreuther C, Simon R, Kähler C, Menz A, Hinsch A, Jacobsen F, Lebok P, Clauditz T, Sauter G, Uhlig R, Wilczak W, Steurer S, Burandt E, Krech R, Dum D, Krech T, Marx A, Minner S
PLoS One 2022;17(7):e0262877. Epub 2022 Jul 21 doi: 10.1371/journal.pone.0262877. PMID: 35862385Free PMC Article
Expression of cytokeratin 20 redefines urothelial papillomas of the bladder.
Harnden P, Mahmood N, Southgate J
Lancet 1999 Mar 20;353(9157):974-7. doi: 10.1016/S0140-6736(98)05383-5. PMID: 10459907
Papillary tumour of the vagina resembling transitional cell carcinoma.
Fetissof F, Haillot O, Lanson Y, Arbeille B, Lansac J
Pathol Res Pract 1990 Jun;186(3):358-64. doi: 10.1016/S0344-0338(11)80294-3. PMID: 2377571
Verrucous acanthosis--so-called verrucous carcinoma--of the esophagus.
Barbier PA, Luder PJ, Wagner HE, Becker CD, Scheurer U, Ruchti C
Z Gastroenterol 1987 Feb;25(2):93-7. PMID: 3564599

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