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Bladder hepatoid adenocarcinoma

MedGen UID:
267739
•Concept ID:
C1511189
•
Neoplastic Process
Synonyms: Bladder Hepatoid Adenocarcinoma; bladder hepatoid adenocarcinoma
 
Monarch Initiative: MONDO:0004459

Definition

A rare variant of bladder adenocarcinoma. It is characterized by the presence of a mixture of polygonal hepatoid cells and glandular adenocarcinoma cells. [from NCI]

Recent clinical studies

Etiology

Hepatoid adenocarcinoma in the urinary bladder. Unusual localization of a newly recognized tumor type.
Sinard J, Macleay L Jr, Melamed J
Cancer 1994 Apr 1;73(7):1919-25. doi: 10.1002/1097-0142(19940401)73:7<1919::aid-cncr2820730724>3.0.co;2-l. PMID: 7511041

Diagnosis

Hepatoid adenocarcinoma in ureter with next-generation sequencing: A case report and literature review.
Lu M, Li Y, Hu D, Yu J, Zheng H, Liu T
BMC Med Genomics 2024 Jan 2;17(1):7. doi: 10.1186/s12920-023-01776-5. PMID: 38167074Free PMC Article
Yolk Sac Tumor in Extragonadal Pelvic Sites: Still a Diagnostic Challenge.
Ravishankar S, Malpica A, Ramalingam P, Euscher ED
Am J Surg Pathol 2017 Jan;41(1):1-11. doi: 10.1097/PAS.0000000000000722. PMID: 27631522
Rare coexistence of mediastinal hepatoid adenocarcinoma, idiopathic azoospermia and horseshoe kidney: a case report and review of the literature.
Hu CH, Li QL, Li HP, Fan SQ, Zhang HX, Liu XL, He Y, Huang M, Lu M, Wang SS, Wu F
Int J Clin Exp Pathol 2015;8(9):11741-6. Epub 2015 Sep 1 PMID: 26617920Free PMC Article
Hepatoid adenocarcinoma of the urinary bladder.
Lopez-Beltran A, Luque RJ, Quintero A, Requena MJ, Montironi R
Virchows Arch 2003 Apr;442(4):381-7. Epub 2003 Mar 25 doi: 10.1007/s00428-003-0772-8. PMID: 12715173
Hepatoid adenocarcinoma of the urinary bladder. An unusual neoplasm.
Burgués O, Ferrer J, Navarro S, Ramos D, Botella E, Llombart-Bosch A
Virchows Arch 1999 Jul;435(1):71-5. doi: 10.1007/s004280050398. PMID: 10431850

Therapy

Rare coexistence of mediastinal hepatoid adenocarcinoma, idiopathic azoospermia and horseshoe kidney: a case report and review of the literature.
Hu CH, Li QL, Li HP, Fan SQ, Zhang HX, Liu XL, He Y, Huang M, Lu M, Wang SS, Wu F
Int J Clin Exp Pathol 2015;8(9):11741-6. Epub 2015 Sep 1 PMID: 26617920Free PMC Article
Hepatoid carcinoma of the ovary and management.
Lazaro J, Rubio D, Repolles M, Capote L
Acta Obstet Gynecol Scand 2007;86(4):498-9. doi: 10.1080/00016340600593117. PMID: 17486476

Prognosis

Hepatoid adenocarcinoma in ureter with next-generation sequencing: A case report and literature review.
Lu M, Li Y, Hu D, Yu J, Zheng H, Liu T
BMC Med Genomics 2024 Jan 2;17(1):7. doi: 10.1186/s12920-023-01776-5. PMID: 38167074Free PMC Article
Liver Metastasis of Urothelial Carcinoma with Hepatoid Features: An Unusual Morphological Finding.
Friedman P, Lai JP
Anticancer Res 2017 Feb;37(2):801-804. doi: 10.21873/anticanres.11380. PMID: 28179333
Rare coexistence of mediastinal hepatoid adenocarcinoma, idiopathic azoospermia and horseshoe kidney: a case report and review of the literature.
Hu CH, Li QL, Li HP, Fan SQ, Zhang HX, Liu XL, He Y, Huang M, Lu M, Wang SS, Wu F
Int J Clin Exp Pathol 2015;8(9):11741-6. Epub 2015 Sep 1 PMID: 26617920Free PMC Article
Hepatoid carcinoma of the ovary and management.
Lazaro J, Rubio D, Repolles M, Capote L
Acta Obstet Gynecol Scand 2007;86(4):498-9. doi: 10.1080/00016340600593117. PMID: 17486476
Hepatoid adenocarcinoma of the lung: report of a case of an unusual alpha-fetoprotein-producing lung tumor.
Arnould L, Drouot F, Fargeot P, Bernard A, Foucher P, Collin F, Petrella T
Am J Surg Pathol 1997 Sep;21(9):1113-8. doi: 10.1097/00000478-199709000-00018. PMID: 9298890

Clinical prediction guides

Yolk Sac Tumor in Extragonadal Pelvic Sites: Still a Diagnostic Challenge.
Ravishankar S, Malpica A, Ramalingam P, Euscher ED
Am J Surg Pathol 2017 Jan;41(1):1-11. doi: 10.1097/PAS.0000000000000722. PMID: 27631522
Rare coexistence of mediastinal hepatoid adenocarcinoma, idiopathic azoospermia and horseshoe kidney: a case report and review of the literature.
Hu CH, Li QL, Li HP, Fan SQ, Zhang HX, Liu XL, He Y, Huang M, Lu M, Wang SS, Wu F
Int J Clin Exp Pathol 2015;8(9):11741-6. Epub 2015 Sep 1 PMID: 26617920Free PMC Article
Albumin gene expression in adenocarcinomas with hepatoid differentiation.
Foschini MP, Baccarini P, Dal Monte PR, Sinard J, Eusebi V, Rosai J
Virchows Arch 1998 Dec;433(6):537-41. doi: 10.1007/s004280050286. PMID: 9870687
Hepatoid adenocarcinoma of the lung: report of a case of an unusual alpha-fetoprotein-producing lung tumor.
Arnould L, Drouot F, Fargeot P, Bernard A, Foucher P, Collin F, Petrella T
Am J Surg Pathol 1997 Sep;21(9):1113-8. doi: 10.1097/00000478-199709000-00018. PMID: 9298890
Alpha-fetoprotein-producing urachal adenocarcinoma.
Lertprasertsuke N, Tsutsumi Y
Acta Pathol Jpn 1991 Apr;41(4):318-26. doi: 10.1111/j.1440-1827.1991.tb03362.x. PMID: 1713733

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