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Breast adenomyoepithelial adenosis

MedGen UID:
267759
•Concept ID:
C1511283
•
Disease or Syndrome
Synonyms: Breast Adenomyoepithelial Adenosis; breast adenomyoepithelial adenosis
 
Monarch Initiative: MONDO:0004181

Definition

An uncommon variant of breast adenosis characterized by the presence of irregularly shaped glands, epithelial cells with eosinophilic cytoplasm, and prominent myopepithelial cells. Mild atypia may be present. [from NCI]

Recent clinical studies

Etiology

Adenomyoepithelial adenosis mimicking phylloides: A diagnostic dilemma.
Singh J, Singhai A, Babu S, Singh K, Mishra A
Indian J Pathol Microbiol 2024 Jan-Mar;67(1):223-225. doi: 10.4103/ijpm.ijpm_925_22. PMID: 38358228
Malignant adenomyoepithelioma of the breast with malignant proliferation of epithelial and myoepithelial elements: a case report and review of the literature.
Ahmed AA, Heller DS
Arch Pathol Lab Med 2000 Apr;124(4):632-6. doi: 10.5858/2000-124-0632-MAOTBW. PMID: 10747327

Diagnosis

Adenomyoepithelial adenosis mimicking phylloides: A diagnostic dilemma.
Singh J, Singhai A, Babu S, Singh K, Mishra A
Indian J Pathol Microbiol 2024 Jan-Mar;67(1):223-225. doi: 10.4103/ijpm.ijpm_925_22. PMID: 38358228
Tubular adenosis of the breast. A distinctive benign lesion mimicking invasive carcinoma.
Lee KC, Chan JK, Gwi E
Am J Surg Pathol 1996 Jan;20(1):46-54. doi: 10.1097/00000478-199601000-00005. PMID: 8540608

Prognosis

Malignant adenomyoepithelioma of the breast with malignant proliferation of epithelial and myoepithelial elements: a case report and review of the literature.
Ahmed AA, Heller DS
Arch Pathol Lab Med 2000 Apr;124(4):632-6. doi: 10.5858/2000-124-0632-MAOTBW. PMID: 10747327
Adenomyoepithelioma of the breast. A report of three cases and review of the literature.
Young RH, Clement PB
Am J Clin Pathol 1988 Mar;89(3):308-14. doi: 10.1093/ajcp/89.3.308. PMID: 2831705
Adenomyoepithelial adenosis and low-grade malignant adenomyoepithelioma of the breast.
Kiaer H, Nielsen B, Paulsen S, Sørensen IM, Dyreborg U, Blichert-Toft M
Virchows Arch A Pathol Anat Histopathol 1984;405(1):55-67. doi: 10.1007/BF00694925. PMID: 6438900

Clinical prediction guides

Adenomyoepithelial adenosis mimicking phylloides: A diagnostic dilemma.
Singh J, Singhai A, Babu S, Singh K, Mishra A
Indian J Pathol Microbiol 2024 Jan-Mar;67(1):223-225. doi: 10.4103/ijpm.ijpm_925_22. PMID: 38358228
Malignant progression of adenomyoepithelial adenosis of the breast.
Tsuda H, Mukai K, Fukutomi T, Hirohashi S
Pathol Int 1994 Jun;44(6):475-9. doi: 10.1111/j.1440-1827.1994.tb01713.x. PMID: 8055115

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