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Prostate Ductal Adenocarcinoma, Cribriform Pattern

MedGen UID:
271028
•Concept ID:
C1514511
•
Neoplastic Process

Definition

A prostate ductal adenocarcinoma characterized by the presence of neoplastic large back-to-back glands with slit-like lumens. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProstate Ductal Adenocarcinoma, Cribriform Pattern

Professional guidelines

PubMed

Review of the Developing Landscape of Prostate Biopsy and Its Roles in Prostate Cancer Diagnosis and Treatment.
Okubo Y, Sato S, Terao H, Yamamoto Y, Suzuki A, Hasegawa C, Yoshioka E, Ono K, Washimi K, Yokose T, Nakaigawa N, Kishida T, Miyagi Y
Arch Esp Urol 2023 Nov;76(9):633-642. doi: 10.56434/j.arch.esp.urol.20237609.78. PMID: 38053418
Diagnostic criteria for ductal adenocarcinoma of the prostate: interobserver variability among 20 expert uropathologists.
Seipel AH, Delahunt B, Samaratunga H, Amin M, Barton J, Berney DM, Billis A, Cheng L, Comperat E, Evans A, Fine SW, Grignon D, Humphrey PA, Magi-Galluzzi C, Montironi R, Sesterhenn I, Srigley JR, Trpkov K, van der Kwast T, Varma M, Zhou M, Ahmad A, Moss S, Egevad L
Histopathology 2014 Aug;65(2):216-27. Epub 2014 Apr 3 doi: 10.1111/his.12382. PMID: 24467262
The utility of Ki-67 expression in the differential diagnosis of prostatic intraepithelial neoplasia and ductal adenocarcinoma.
Rioux-Leclercq N, Leray E, Patard JJ, Lobel B, Guillé F, Jouan F, Bellaud P, Epstein JI
Hum Pathol 2005 May;36(5):531-5. doi: 10.1016/j.humpath.2005.01.021. PMID: 15948120

Recent clinical studies

Etiology

Review of the Developing Landscape of Prostate Biopsy and Its Roles in Prostate Cancer Diagnosis and Treatment.
Okubo Y, Sato S, Terao H, Yamamoto Y, Suzuki A, Hasegawa C, Yoshioka E, Ono K, Washimi K, Yokose T, Nakaigawa N, Kishida T, Miyagi Y
Arch Esp Urol 2023 Nov;76(9):633-642. doi: 10.56434/j.arch.esp.urol.20237609.78. PMID: 38053418
Impact of comedonecrosis on prostate cancer outcome: a systematic review.
Aiyer KTS, Kroon LJ, van Leenders GJLH
Histopathology 2023 Sep;83(3):339-347. Epub 2023 May 17 doi: 10.1111/his.14945. PMID: 37195595
Prostatic ductal adenocarcinoma with cribriform architecture has worse prognostic features than non-cribriform-type.
Au S, Villamil CF, Alaghehbandan R, Wang G
Ann Diagn Pathol 2019 Apr;39:59-62. Epub 2019 Feb 10 doi: 10.1016/j.anndiagpath.2019.02.007. PMID: 30772651
PIN-like (Ductal) Adenocarcinoma of the Prostate.
Paulk A, Giannico G, Epstein JI
Am J Surg Pathol 2018 Dec;42(12):1693-1700. doi: 10.1097/PAS.0000000000001139. PMID: 30138215
Spectrum of Cribriform Proliferations of the Prostate: From Benign to Malignant.
Lee TK, Ro JY
Arch Pathol Lab Med 2018 Aug;142(8):938-946. doi: 10.5858/arpa.2018-0005-RA. PMID: 30040459

Diagnosis

WHO Classification of Tumours fifth edition: evolving issues in the classification, diagnosis, and prognostication of prostate cancer.
Kench JG, Amin MB, Berney DM, Compérat EM, Cree IA, Gill AJ, Hartmann A, Menon S, Moch H, Netto GJ, Raspollini MR, Rubin MA, Tan PH, Tsuzuki T, Turjalic S, van der Kwast TH, Zhou M, Srigley JR
Histopathology 2022 Oct;81(4):447-458. Epub 2022 Aug 2 doi: 10.1111/his.14711. PMID: 35758185Free PMC Article
The 2019 International Society of Urological Pathology (ISUP) Consensus Conference on Grading of Prostatic Carcinoma.
van Leenders GJLH, van der Kwast TH, Grignon DJ, Evans AJ, Kristiansen G, Kweldam CF, Litjens G, McKenney JK, Melamed J, Mottet N, Paner GP, Samaratunga H, Schoots IG, Simko JP, Tsuzuki T, Varma M, Warren AY, Wheeler TM, Williamson SR, Iczkowski KA; ISUP Grading Workshop Panel Members
Am J Surg Pathol 2020 Aug;44(8):e87-e99. doi: 10.1097/PAS.0000000000001497. PMID: 32459716Free PMC Article
Evolution of prostate cancer histopathology.
Compérat E
Curr Opin Urol 2019 Nov;29(6):587-592. doi: 10.1097/MOU.0000000000000669. PMID: 31453865
Large-Gland Proliferations of the Prostate.
Iczkowski KA
Surg Pathol Clin 2018 Dec;11(4):687-712. Epub 2018 Oct 17 doi: 10.1016/j.path.2018.07.001. PMID: 30447836
PIN-like (Ductal) Adenocarcinoma of the Prostate.
Paulk A, Giannico G, Epstein JI
Am J Surg Pathol 2018 Dec;42(12):1693-1700. doi: 10.1097/PAS.0000000000001139. PMID: 30138215

Therapy

Differential response to neoadjuvant hormonal therapy in prostate cancer: Predictive morphological parameters and molecular markers.
Wang X, Qi M, Zhang J, Sun X, Guo H, Pang Y, Zhang Q, Chen X, Zhang R, Liu Z, Liu L, Hao X, Han B
Prostate 2019 May;79(7):709-719. Epub 2019 Mar 2 doi: 10.1002/pros.23777. PMID: 30825345
High-grade prostatic intraepithelial neoplasialike ductal adenocarcinoma of the prostate: a clinicopathologic study of 28 cases.
Tavora F, Epstein JI
Am J Surg Pathol 2008 Jul;32(7):1060-7. doi: 10.1097/PAS.0b013e318160edaf. PMID: 18496142

Prognosis

WHO Classification of Tumours fifth edition: evolving issues in the classification, diagnosis, and prognostication of prostate cancer.
Kench JG, Amin MB, Berney DM, Compérat EM, Cree IA, Gill AJ, Hartmann A, Menon S, Moch H, Netto GJ, Raspollini MR, Rubin MA, Tan PH, Tsuzuki T, Turjalic S, van der Kwast TH, Zhou M, Srigley JR
Histopathology 2022 Oct;81(4):447-458. Epub 2022 Aug 2 doi: 10.1111/his.14711. PMID: 35758185Free PMC Article
The 2019 International Society of Urological Pathology (ISUP) Consensus Conference on Grading of Prostatic Carcinoma.
van Leenders GJLH, van der Kwast TH, Grignon DJ, Evans AJ, Kristiansen G, Kweldam CF, Litjens G, McKenney JK, Melamed J, Mottet N, Paner GP, Samaratunga H, Schoots IG, Simko JP, Tsuzuki T, Varma M, Warren AY, Wheeler TM, Williamson SR, Iczkowski KA; ISUP Grading Workshop Panel Members
Am J Surg Pathol 2020 Aug;44(8):e87-e99. doi: 10.1097/PAS.0000000000001497. PMID: 32459716Free PMC Article
Prostatic ductal adenocarcinoma with cribriform architecture has worse prognostic features than non-cribriform-type.
Au S, Villamil CF, Alaghehbandan R, Wang G
Ann Diagn Pathol 2019 Apr;39:59-62. Epub 2019 Feb 10 doi: 10.1016/j.anndiagpath.2019.02.007. PMID: 30772651
Large-Gland Proliferations of the Prostate.
Iczkowski KA
Surg Pathol Clin 2018 Dec;11(4):687-712. Epub 2018 Oct 17 doi: 10.1016/j.path.2018.07.001. PMID: 30447836
Spectrum of Cribriform Proliferations of the Prostate: From Benign to Malignant.
Lee TK, Ro JY
Arch Pathol Lab Med 2018 Aug;142(8):938-946. doi: 10.5858/arpa.2018-0005-RA. PMID: 30040459

Clinical prediction guides

Review of the Developing Landscape of Prostate Biopsy and Its Roles in Prostate Cancer Diagnosis and Treatment.
Okubo Y, Sato S, Terao H, Yamamoto Y, Suzuki A, Hasegawa C, Yoshioka E, Ono K, Washimi K, Yokose T, Nakaigawa N, Kishida T, Miyagi Y
Arch Esp Urol 2023 Nov;76(9):633-642. doi: 10.56434/j.arch.esp.urol.20237609.78. PMID: 38053418
The 2019 International Society of Urological Pathology (ISUP) Consensus Conference on Grading of Prostatic Carcinoma.
van Leenders GJLH, van der Kwast TH, Grignon DJ, Evans AJ, Kristiansen G, Kweldam CF, Litjens G, McKenney JK, Melamed J, Mottet N, Paner GP, Samaratunga H, Schoots IG, Simko JP, Tsuzuki T, Varma M, Warren AY, Wheeler TM, Williamson SR, Iczkowski KA; ISUP Grading Workshop Panel Members
Am J Surg Pathol 2020 Aug;44(8):e87-e99. doi: 10.1097/PAS.0000000000001497. PMID: 32459716Free PMC Article
Correlation between cribriform/intraductal prostatic adenocarcinoma and percent Gleason pattern 4 to a 22-gene genomic classifier.
Taylor AS, Morgan TM, Wallington DG, Chinnaiyan AM, Spratt DE, Mehra R
Prostate 2020 Feb;80(2):146-152. Epub 2019 Nov 18 doi: 10.1002/pros.23926. PMID: 31737920Free PMC Article
Prostatic ductal adenocarcinoma with cribriform architecture has worse prognostic features than non-cribriform-type.
Au S, Villamil CF, Alaghehbandan R, Wang G
Ann Diagn Pathol 2019 Apr;39:59-62. Epub 2019 Feb 10 doi: 10.1016/j.anndiagpath.2019.02.007. PMID: 30772651
PIN-like (Ductal) Adenocarcinoma of the Prostate.
Paulk A, Giannico G, Epstein JI
Am J Surg Pathol 2018 Dec;42(12):1693-1700. doi: 10.1097/PAS.0000000000001139. PMID: 30138215

Recent systematic reviews

Impact of comedonecrosis on prostate cancer outcome: a systematic review.
Aiyer KTS, Kroon LJ, van Leenders GJLH
Histopathology 2023 Sep;83(3):339-347. Epub 2023 May 17 doi: 10.1111/his.14945. PMID: 37195595
Impact of Epithelial Histological Types, Subtypes, and Growth Patterns on Oncological Outcomes for Patients with Nonmetastatic Prostate Cancer Treated with Curative Intent: A Systematic Review.
Marra G, van Leenders GJLH, Zattoni F, Kesch C, Rajwa P, Cornford P, van der Kwast T, van den Bergh RCN, Briers E, Van den Broeck T, De Meerleer G, De Santis M, Eberli D, Farolfi A, Gillessen S, Grivas N, Grummet JP, Henry AM, Lardas M, Lieuw M, Linares Espinós E, Mason MD, O'Hanlon S, van Oort IM, Oprea-Lager DE, Ploussard G, Rouvière O, Schoots IG, Stranne J, Tilki D, Wiegel T, Willemse PM, Mottet N, Gandaglia G; European Association of Urology Young Academic Urologists Prostate Cancer Working Group, the EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines Panel on Prostate Cancer
Eur Urol 2023 Jul;84(1):65-85. Epub 2023 Apr 27 doi: 10.1016/j.eururo.2023.03.014. PMID: 37117107

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