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Breast Atypical Ductal Hyperplasia

MedGen UID:
272327
Concept ID:
C1332347
Neoplastic Process
Synonyms: Atypical Ductal Hyperplasia; Atypical Ductal Hyperplasias; Ductal Hyperplasia, Atypical; Ductal Hyperplasias, Atypical; Hyperplasia, Atypical Ductal; Hyperplasias, Atypical Ductal
SNOMED CT: Atypical mammary duct hyperplasia (427785007); Atypical hyperplasia of lactiferous duct (427785007); Atypical ductal hyperplasia of breast (427785007)

Definition

A neoplastic process that arises from the terminal ductal lobular unit of the breast parenchyma. It is usually solitary and confined to a single lobular unit. It is characterized by the presence of a monomorphic epithelial proliferation in a cribriform, micropapillary, or solid growth pattern. Focal architectural features of low grade ductal carcinoma in situ are present. There is an increased risk for development of invasive breast carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBreast Atypical Ductal Hyperplasia

Professional guidelines

PubMed

Farante G, Toesca A, Magnoni F, Lissidini G, Vila J, Mastropasqua M, Viale G, Penco S, Cassano E, Lazzeroni M, Bonanni B, Leonardi MC, Ripoll-Orts F, Curigliano G, Orecchia R, Galimberti V, Veronesi P
Eur J Surg Oncol 2022 Apr;48(4):736-741. Epub 2021 Nov 9 doi: 10.1016/j.ejso.2021.10.030. PMID: 34772587
Zehr KR
Radiol Technol 2019 Sep;91(1):51M-61M. PMID: 31471487
Correa C, Harris EE, Leonardi MC, Smith BD, Taghian AG, Thompson AM, White J, Harris JR
Pract Radiat Oncol 2017 Mar-Apr;7(2):73-79. Epub 2016 Sep 17 doi: 10.1016/j.prro.2016.09.007. PMID: 27866865

Recent clinical studies

Etiology

González Mariño MA
Breast Dis 2022;41(1):545-550. doi: 10.3233/BD-220029. PMID: 36683493
Schiaffino S, Cozzi A, Sardanelli F
Br J Radiol 2020 Jun;93(1110):20200117. Epub 2020 Apr 1 doi: 10.1259/bjr.20200117. PMID: 32207989Free PMC Article

Diagnosis

González Mariño MA
Breast Dis 2022;41(1):545-550. doi: 10.3233/BD-220029. PMID: 36683493
Liu TT, Li XF, Wang L, Yang JL
Cancer Biomark 2020;28(3):293-299. doi: 10.3233/CBM-190196. PMID: 32390595
Schiaffino S, Cozzi A, Sardanelli F
Br J Radiol 2020 Jun;93(1110):20200117. Epub 2020 Apr 1 doi: 10.1259/bjr.20200117. PMID: 32207989Free PMC Article

Therapy

Schiaffino S, Cozzi A, Sardanelli F
Br J Radiol 2020 Jun;93(1110):20200117. Epub 2020 Apr 1 doi: 10.1259/bjr.20200117. PMID: 32207989Free PMC Article

Prognosis

Liu TT, Li XF, Wang L, Yang JL
Cancer Biomark 2020;28(3):293-299. doi: 10.3233/CBM-190196. PMID: 32390595
Schiaffino S, Cozzi A, Sardanelli F
Br J Radiol 2020 Jun;93(1110):20200117. Epub 2020 Apr 1 doi: 10.1259/bjr.20200117. PMID: 32207989Free PMC Article
Brandwein-Gensler M, Hille J, Wang BY, Urken M, Gordon R, Wang LJ, Simpson JR, Simpson RH, Gnepp DR
Am J Surg Pathol 2004 Aug;28(8):1040-4. doi: 10.1097/01.pas.0000128662.66321.be. PMID: 15252310

Clinical prediction guides

González Mariño MA
Breast Dis 2022;41(1):545-550. doi: 10.3233/BD-220029. PMID: 36683493
Liu TT, Li XF, Wang L, Yang JL
Cancer Biomark 2020;28(3):293-299. doi: 10.3233/CBM-190196. PMID: 32390595
Schiaffino S, Cozzi A, Sardanelli F
Br J Radiol 2020 Jun;93(1110):20200117. Epub 2020 Apr 1 doi: 10.1259/bjr.20200117. PMID: 32207989Free PMC Article

Recent systematic reviews

González Mariño MA
Breast Dis 2022;41(1):545-550. doi: 10.3233/BD-220029. PMID: 36683493

Supplemental Content

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