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Breast fibrosarcoma

MedGen UID:
272385
•Concept ID:
C1332630
•
Neoplastic Process
Synonyms: Breast Fibrosarcoma; breast fibrosarcoma; breast fibrosarcoma (disease); Fibrosarcoma of Breast; fibrosarcoma of breast; Fibrosarcoma of the Breast; fibrosarcoma of the breast
 
Monarch Initiative: MONDO:0003728

Definition

A usually aggressive malignant neoplasm arising from the breast. It is characterized by the presence of spindle-shaped fibroblasts and collagenous stroma formation in a herringbone growth pattern. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBreast fibrosarcoma

Professional guidelines

PubMed

Angiosarcoma associated with radiation therapy after treatment of breast cancer. Retrospective study on ten years.
Verdin V, Mattart L, Cusumano PG, De Hertogh O, De Meester C, Francart D, Kirova YM, Nelissen X, Sacino F, Vanderick J, Weerts J, Markiewicz S
Cancer Radiother 2021 Apr;25(2):114-118. Epub 2021 Jan 22 doi: 10.1016/j.canrad.2020.05.020. PMID: 33487559
The Evolving Diagnostic and Treatment Landscape of NTRK-Fusion-Driven Pediatric Cancers.
Shulman DS, DuBois SG
Paediatr Drugs 2020 Apr;22(2):189-197. doi: 10.1007/s40272-020-00380-9. PMID: 31965543
Differential Diagnosis of Benign Spindle Cell Lesions.
Magro G
Surg Pathol Clin 2018 Mar;11(1):91-121. Epub 2017 Dec 9 doi: 10.1016/j.path.2017.09.005. PMID: 29413661

Recent clinical studies

Diagnosis

A malignant transformation of borderline phyllodes tumor to fibrosarcoma breast: A rare case report.
Kumar M, Sagar M, Vimal JK, Kumar V
J Cancer Res Ther 2023 Jan 1;19(Suppl 2):S892-S895. Epub 2023 Apr 27 doi: 10.4103/jcrt.jcrt_378_21. PMID: 38384072
Primary Fibrosarcoma of the Breast: Case Report of a Rare Breast Neoplasm.
Raphael S, Onyedi CE, Nwana EJC, Garba ES
West Afr J Med 2021 Jul 29;38(7):701-704. PMID: 34331529

Prognosis

A malignant transformation of borderline phyllodes tumor to fibrosarcoma breast: A rare case report.
Kumar M, Sagar M, Vimal JK, Kumar V
J Cancer Res Ther 2023 Jan 1;19(Suppl 2):S892-S895. Epub 2023 Apr 27 doi: 10.4103/jcrt.jcrt_378_21. PMID: 38384072

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