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Lung inflammatory myofibroblastic tumor

MedGen UID:
273512
Concept ID:
C1518038
Neoplastic Process
Synonyms: inflammatory myofibroblastic lung tumor; inflammatory myofibroblastic lung tumour; Lung Inflammatory Myofibroblastic Tumor; lung inflammatory myofibroblastic tumor
 
Monarch Initiative: MONDO:0006276

Definition

An intermediate fibroblastic neoplasm arising from the lung. It is characterized by the presence of spindle-shaped fibroblasts and myofibroblasts, and a chronic inflammatory infiltrate composed of eosinophils, lymphocytes and plasma cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLung inflammatory myofibroblastic tumor

Professional guidelines

PubMed

Mukhopadhyay S
Semin Diagn Pathol 2024 Mar;41(2):72-78. Epub 2023 Nov 15 doi: 10.1053/j.semdp.2023.11.006. PMID: 37993385
Zheng S, Shu J, Xue J, Ying C
J Healthc Eng 2022;2022:3547070. Epub 2022 Jan 3 doi: 10.1155/2022/3547070. PMID: 35028118Free PMC Article
Coffin CM, Dehner LP, Meis-Kindblom JM
Semin Diagn Pathol 1998 May;15(2):102-10. PMID: 9606802

Recent clinical studies

Etiology

Devins KM, Samore W, Nielsen GP, Deshpande V, Oliva E
Mod Pathol 2023 Jun;36(6):100143. Epub 2023 Feb 18 doi: 10.1016/j.modpat.2023.100143. PMID: 36806735
Zheng S, Shu J, Xue J, Ying C
J Healthc Eng 2022;2022:3547070. Epub 2022 Jan 3 doi: 10.1155/2022/3547070. PMID: 35028118Free PMC Article
Shukla PS, Mittal K
Arch Pathol Lab Med 2019 Jan;143(1):122-129. Epub 2018 Jul 2 doi: 10.5858/arpa.2017-0575-RA. PMID: 29965784
Lichtenberger JP 3rd, Biko DM, Carter BW, Pavio MA, Huppmann AR, Chung EM
Radiographics 2018 Nov-Dec;38(7):2151-2172. doi: 10.1148/rg.2018180192. PMID: 30422774
Kovach SJ, Fischer AC, Katzman PJ, Salloum RM, Ettinghausen SE, Madeb R, Koniaris LG
J Surg Oncol 2006 Oct 1;94(5):385-91. doi: 10.1002/jso.20516. PMID: 16967468

Diagnosis

Mahajan P, Casanova M, Ferrari A, Fordham A, Trahair T, Venkatramani R
Curr Probl Cancer 2021 Aug;45(4):100768. Epub 2021 Jul 1 doi: 10.1016/j.currproblcancer.2021.100768. PMID: 34244015
Khatri A, Agrawal A, Sikachi RR, Mehta D, Sahni S, Meena N
Adv Respir Med 2018;86(1):27-35. doi: 10.5603/ARM.2018.0007. PMID: 29490419
Surabhi VR, Chua S, Patel RP, Takahashi N, Lalwani N, Prasad SR
Radiol Clin North Am 2016 May;54(3):553-63. Epub 2016 Mar 12 doi: 10.1016/j.rcl.2015.12.005. PMID: 27153788
Minoo P, Wang HY
Int J Clin Exp Pathol 2012;5(5):397-410. Epub 2012 May 23 PMID: 22808292Free PMC Article
Yi E, Aubry MC
Arch Pathol Lab Med 2010 Mar;134(3):417-26. doi: 10.5858/134.3.417. PMID: 20196669

Therapy

Wang QA, Chen HW, Wu RC, Wu CE
Curr Treat Options Oncol 2023 Dec;24(12):1683-1702. Epub 2023 Nov 8 doi: 10.1007/s11864-023-01144-6. PMID: 37938503Free PMC Article
Mahajan P, Casanova M, Ferrari A, Fordham A, Trahair T, Venkatramani R
Curr Probl Cancer 2021 Aug;45(4):100768. Epub 2021 Jul 1 doi: 10.1016/j.currproblcancer.2021.100768. PMID: 34244015
Pal P, Khan Z
J Clin Pathol 2017 Dec;70(12):1001-1009. Epub 2017 Sep 13 doi: 10.1136/jclinpath-2016-204244. PMID: 28903995
Minoo P, Wang HY
Int J Clin Exp Pathol 2012;5(5):397-410. Epub 2012 May 23 PMID: 22808292Free PMC Article
Kamisawa T, Okamoto A
World J Gastroenterol 2008 Jul 7;14(25):3948-55. doi: 10.3748/wjg.14.3948. PMID: 18609677Free PMC Article

Prognosis

Chen B, Chan WN, Xie F, Mui CW, Liu X, Cheung AHK, Lung RWM, Chow C, Zhang Z, Fang C, Yu P, Shi S, Zhou S, Chen G, Wang Z, Wang S, Ding X, Huang B, Liang L, Dong Y, Wong CC, Wu WKK, Cheng ASL, Wong N, Yu J, Lo KW, Tse GMK, Kang W, To KF
Clin Transl Med 2023 Dec;13(12):e1516. doi: 10.1002/ctm2.1516. PMID: 38148640Free PMC Article
Ramos JG, Ochoa A, Cicutti S, Del Rio R, Lubienieki F
Childs Nerv Syst 2023 May;39(5):1137-1145. Epub 2023 Apr 5 doi: 10.1007/s00381-023-05925-0. PMID: 37017800
Khatri A, Agrawal A, Sikachi RR, Mehta D, Sahni S, Meena N
Adv Respir Med 2018;86(1):27-35. doi: 10.5603/ARM.2018.0007. PMID: 29490419
Kovach SJ, Fischer AC, Katzman PJ, Salloum RM, Ettinghausen SE, Madeb R, Koniaris LG
J Surg Oncol 2006 Oct 1;94(5):385-91. doi: 10.1002/jso.20516. PMID: 16967468
Coffin CM, Humphrey PA, Dehner LP
Semin Diagn Pathol 1998 May;15(2):85-101. PMID: 9606801

Clinical prediction guides

Yuan C, Fan J, Xu L
Medicine (Baltimore) 2023 Dec 15;102(50):e36558. doi: 10.1097/MD.0000000000036558. PMID: 38115338Free PMC Article
Zhu Z, Zha Y, Wang W, Wang X, Gao Y, Lv W
Biomed Res Int 2018;2018:7928241. Epub 2018 Oct 15 doi: 10.1155/2018/7928241. PMID: 30410939Free PMC Article
Kato T, Tomita S, Tamaki M, Yutani C, Okawa Y
Heart Vessels 2014 Jan;29(1):123-8. Epub 2013 Apr 11 doi: 10.1007/s00380-013-0344-z. PMID: 23575661
Davies KD, Doebele RC
Clin Cancer Res 2013 Aug 1;19(15):4040-5. Epub 2013 May 29 doi: 10.1158/1078-0432.CCR-12-2851. PMID: 23719267Free PMC Article
Kovach SJ, Fischer AC, Katzman PJ, Salloum RM, Ettinghausen SE, Madeb R, Koniaris LG
J Surg Oncol 2006 Oct 1;94(5):385-91. doi: 10.1002/jso.20516. PMID: 16967468

Recent systematic reviews

Chanthong S, Sathitsamitphong L, Natesirinilkul R, Charoenkwan P, Suwansirikul S, Choed-Amphai C
Childs Nerv Syst 2023 Feb;39(2):331-342. Epub 2022 Dec 14 doi: 10.1007/s00381-022-05789-w. PMID: 36515740

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