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Endometrial undifferentiated carcinoma

MedGen UID:
274013
•Concept ID:
C1516865
•
Neoplastic Process
Synonyms: Endometrial Undifferentiated Carcinoma; endometrial undifferentiated carcinoma; Primary undifferentiated carcinoma of endometrium; Undifferentiated Endometrial Carcinoma; undifferentiated endometrial carcinoma
SNOMED CT: Primary undifferentiated carcinoma of endometrium (733360000)
 
Monarch Initiative: MONDO:0006199

Definition

A primary carcinoma of the endometrium characterized by the presence of malignant cells that lack evidence of differentiation. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEndometrial undifferentiated carcinoma

Professional guidelines

PubMed

The value of SOX2 in the differential diagnosis of SMARCA4 (BRG1)-deficient uterine neoplasms.
Zheng L, Zhang L, Wang XI, Katz G, Tandon N, Zhao B, Lucci J, Ding J, Zhang S
Hum Pathol 2022 Jun;124:45-55. Epub 2022 Mar 22 doi: 10.1016/j.humpath.2022.03.009. PMID: 35331811
Undifferentiated endometrial carcinoma: a National Cancer Database analysis of prognostic factors and treatment outcomes.
AlHilli M, Elson P, Rybicki L, Amarnath S, Yang B, Michener CM, Rose PG
Int J Gynecol Cancer 2019 Sep;29(7):1126-1133. Epub 2019 Aug 17 doi: 10.1136/ijgc-2019-000465. PMID: 31422353
Undifferentiated Endometrial Carcinomas: Clinicopathologic Characteristics and Treatment Outcomes.
Ganju RG, Tawfik O, Brown L, Chen AM, Jewell A, TenNapel M, Hoover A
Int J Gynecol Cancer 2018 Sep;28(7):1271-1277. doi: 10.1097/IGC.0000000000001302. PMID: 30036218

Recent clinical studies

Etiology

Undifferentiated carcinoma of the endometrium.
Altrabulsi B, Malpica A, Deavers MT, Bodurka DC, Broaddus R, Silva EG
Am J Surg Pathol 2005 Oct;29(10):1316-21. doi: 10.1097/01.pas.0000171003.72352.9a. PMID: 16160474

Diagnosis

Undifferentiated carcinoma of the endometrium.
Altrabulsi B, Malpica A, Deavers MT, Bodurka DC, Broaddus R, Silva EG
Am J Surg Pathol 2005 Oct;29(10):1316-21. doi: 10.1097/01.pas.0000171003.72352.9a. PMID: 16160474

Prognosis

Undifferentiated carcinoma of the endometrium.
Altrabulsi B, Malpica A, Deavers MT, Bodurka DC, Broaddus R, Silva EG
Am J Surg Pathol 2005 Oct;29(10):1316-21. doi: 10.1097/01.pas.0000171003.72352.9a. PMID: 16160474

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