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Vulvar leiomyoma

MedGen UID:
274417
•Concept ID:
C1520087
•
Neoplastic Process
Synonyms: leiomyoma of mammalian vulva; mammalian vulva leiomyoma; Vulvar Leiomyoma; vulvar leiomyoma
 
Monarch Initiative: MONDO:0003298

Definition

A benign smooth muscle neoplasm arising from the vulva. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVulvar leiomyoma

Professional guidelines

PubMed

Epigallocatechin Gallate for the Treatment of Benign and Malignant Gynecological Diseases-Focus on Epigenetic Mechanisms.
Włodarczyk M, Ciebiera M, Nowicka G, Łoziński T, Ali M, Al-Hendy A
Nutrients 2024 Feb 17;16(4) doi: 10.3390/nu16040559. PMID: 38398883Free PMC Article
Chronic Pelvic Pain: ACOG Practice Bulletin, Number 218.
Obstet Gynecol 2020 Mar;135(3):e98-e109. doi: 10.1097/AOG.0000000000003716. PMID: 32080051
Leiomyoma cutis: a focused review on presentation, management, and association with malignancy.
Malik K, Patel P, Chen J, Khachemoune A
Am J Clin Dermatol 2015 Feb;16(1):35-46. doi: 10.1007/s40257-015-0112-1. PMID: 25605645

Recent clinical studies

Etiology

Vulvar leiomyoma in a postmenopausal woman.
Redlin T, Bishop B, Durkin T, Hultgren E
BMJ Case Rep 2024 Mar 5;17(3) doi: 10.1136/bcr-2023-255002. PMID: 38442969Free PMC Article
Vulvar leiomyoma: a case report.
Ammouri S, Elkarkri C, Zeraidi N, Lakhdar A, Baydada A
Pan Afr Med J 2019;32:208. Epub 2019 Apr 29 doi: 10.11604/pamj.2019.32.208.18480. PMID: 31312320Free PMC Article

Diagnosis

Leiomyoma of the Vulva: Case Report.
Fontinele DRDS, Silva LHC, Vieira SC, Pinheiro FDCS, Nunes GA
J Pediatr Adolesc Gynecol 2022 Jun;35(3):391-392. Epub 2021 Nov 10 doi: 10.1016/j.jpag.2021.10.020. PMID: 34767968
Vulvar Leiomyoma Presenting as a Painless Vulvar Mass.
Witherspoon C, Garcia B, Behbehani S, Nahas S, Stuparich MA
J Minim Invasive Gynecol 2022 Feb;29(2):187-189. Epub 2021 Nov 5 doi: 10.1016/j.jmig.2021.10.014. PMID: 34748966
Vulvar leiomyoma: a case report.
Ammouri S, Elkarkri C, Zeraidi N, Lakhdar A, Baydada A
Pan Afr Med J 2019;32:208. Epub 2019 Apr 29 doi: 10.11604/pamj.2019.32.208.18480. PMID: 31312320Free PMC Article
Review of the pathophysiology, diagnosis, and therapy of vulvar leiomyoma, a rare gynecological tumor.
Sun C, Zou J, Wang Q, Wang Q, Han L, Batchu N, Ulain Q, Du J, Lv S, Song Q, Li Q
J Int Med Res 2018 Feb;46(2):663-674. Epub 2017 Sep 6 doi: 10.1177/0300060517721796. PMID: 28875758Free PMC Article
Vulvar leiomyoma.
Neri A, Peled Y, Braslavski D
Acta Obstet Gynecol Scand 1993 Apr;72(3):221-2. doi: 10.3109/00016349309013377. PMID: 8385861

Therapy

Vulvar leiomyoma associated with estrogen/progestin therapy. A case report.
Siegle JC, Cartmell L
J Reprod Med 1995 Feb;40(2):147-8. PMID: 7738927

Prognosis

Vulvar leiomyoma: a case report.
Ammouri S, Elkarkri C, Zeraidi N, Lakhdar A, Baydada A
Pan Afr Med J 2019;32:208. Epub 2019 Apr 29 doi: 10.11604/pamj.2019.32.208.18480. PMID: 31312320Free PMC Article

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