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Monomorphic T/NK-Cell Post-Transplant Lymphoproliferative Disorder

MedGen UID:
277380
Concept ID:
C1334799
Neoplastic Process
Synonyms: Monomorphic T-Cell Post-Transplant Lymphoproliferative Disorder; Monomorphic T-Cell PTLD

Definition

A clonal T-cell lymphoproliferative disorder arising as a result of post-transplant immunosuppression therapy. It is characterized by destructive infiltration of lymph nodes and extranodal sites by a monotonous population of transformed T-lymphocytes/NK-cells. The clonal cellular infiltrates fulfill the criteria for any of the T-cell or natural killer cell lymphomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMonomorphic T/NK-Cell Post-Transplant Lymphoproliferative Disorder

Professional guidelines

PubMed

Al-Mansour Z, Nelson BP, Evens AM
Curr Hematol Malig Rep 2013 Sep;8(3):173-83. doi: 10.1007/s11899-013-0162-5. PMID: 23737188Free PMC Article

Recent clinical studies

Etiology

Al-Mansour Z, Nelson BP, Evens AM
Curr Hematol Malig Rep 2013 Sep;8(3):173-83. doi: 10.1007/s11899-013-0162-5. PMID: 23737188Free PMC Article

Diagnosis

Al-Mansour Z, Nelson BP, Evens AM
Curr Hematol Malig Rep 2013 Sep;8(3):173-83. doi: 10.1007/s11899-013-0162-5. PMID: 23737188Free PMC Article

Therapy

Al-Mansour Z, Nelson BP, Evens AM
Curr Hematol Malig Rep 2013 Sep;8(3):173-83. doi: 10.1007/s11899-013-0162-5. PMID: 23737188Free PMC Article

Supplemental Content

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