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Multiple Pulmonary Hamartomas

MedGen UID:
277385
•Concept ID:
C1334824
•
Neoplastic Process
Synonyms: Multiple Chondromatous Hamartoma of Lung; Multiple Chondromatous Hamartoma of the Lung; Multiple Chondromatous Lung Hamartoma; Multiple hamartoma of lung; Multiple Lung Hamartomas; Multiple pulmonary hamartomas
SNOMED CT: Multiple pulmonary hamartomas (707382005); Multiple hamartoma of lung (707382005)

Definition

The presence of multiple hamartomas in the lungs. Hamartomas are usually solitary lesions on chest-x-rays. Multiple lung hamartomas are rare. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMultiple Pulmonary Hamartomas

Professional guidelines

PubMed

French recommendations for the diagnosis and management of lymphangioleiomyomatosis.
Cottin V, Blanchard E, Kerjouan M, Lazor R, Reynaud-Gaubert M, Taille C, Uzunhan Y, Wemeau L, Andrejak C, Baud D, Bonniaud P, Brillet PY, Calender A, Chalabreysse L, Court-Fortune I, Desbaillets NP, Ferretti G, Guillemot A, Hardelin L, Kambouchner M, Leclerc V, Lederlin M, Malinge MC, Mancel A, Marchand-Adam S, Maury JM, Naccache JM, Nasser M, Nunes H, Pagnoux G, Prévot G, Rousset-Jablonski C, Rouviere O, Si-Mohamed S, Touraine R, Traclet J, Turquier S, Vagnarelli S, Ahmad K; OrphaLung network
Respir Med Res 2023 Jun;83:101010. Epub 2023 Mar 24 doi: 10.1016/j.resmer.2023.101010. PMID: 37087906
Updated International Tuberous Sclerosis Complex Diagnostic Criteria and Surveillance and Management Recommendations.
Northrup H, Aronow ME, Bebin EM, Bissler J, Darling TN, de Vries PJ, Frost MD, Fuchs Z, Gosnell ES, Gupta N, Jansen AC, Jóźwiak S, Kingswood JC, Knilans TK, McCormack FX, Pounders A, Roberds SL, Rodriguez-Buritica DF, Roth J, Sampson JR, Sparagana S, Thiele EA, Weiner HL, Wheless JW, Towbin AJ, Krueger DA; International Tuberous Sclerosis Complex Consensus Group
Pediatr Neurol 2021 Oct;123:50-66. Epub 2021 Jul 24 doi: 10.1016/j.pediatrneurol.2021.07.011. PMID: 34399110
Tuberous sclerosis complex: review based on new diagnostic criteria.
Portocarrero LKL, Quental KN, Samorano LP, Oliveira ZNP, Rivitti-Machado MCDM
An Bras Dermatol 2018 Jun;93(3):323-331. doi: 10.1590/abd1806-4841.20186972. PMID: 29924239Free PMC Article

Recent clinical studies

Etiology

Multiple pulmonary hamartomas: report of a case.
Inoue M, Tanaka I, Masuda R, Huruhata Y, Takemura T
Surg Today 1994;24(12):1090-2. doi: 10.1007/BF01367462. PMID: 7780233

Diagnosis

A child with multiple pulmonary hamartomas initially thought to be metastasis of Wilms' tumour.
Altuntas B, Demirci E, Yildirim Z, Aydin Y, Eroglu A
Br J Hosp Med (Lond) 2021 Mar 2;82(3):1-3. Epub 2021 Mar 3 doi: 10.12968/hmed.2020.0374. PMID: 33792380
A pulmonary chondromatous hamartoma resembling multiple metastases in the (18)F-FDG PET/CT scan.
Li L, Jiang C, Tian R
Hell J Nucl Med 2016 May-Aug;19(2):176-8. Epub 2016 Jun 22 doi: 10.1967/s002449910376. PMID: 27331216
Recurring pulmonary hamartomas: cause for concern?
Coleman N, Chotirmall SH, Forman E, Broe P, Royston D, O'Neill S
Ir Med J 2013 Oct;106(9):279-80. PMID: 24416852
Multiple pulmonary hamartomas penetrating the visceral pleura: report of a case.
Teramoto K, Suzumura Y
Surg Today 2007;37(12):1087-9. Epub 2007 Nov 26 doi: 10.1007/s00595-007-3552-2. PMID: 18030571
Multiple pulmonary hamartomas; a case report and review of the literature.
Nili M, Vidne BA, Avidor I, Paz R, Levy MJ
Scand J Thorac Cardiovasc Surg 1979;13(2):157-60. doi: 10.3109/14017437909100984. PMID: 472676

Prognosis

Multiple pulmonary hamartomas: report of a case.
Inoue M, Tanaka I, Masuda R, Huruhata Y, Takemura T
Surg Today 1994;24(12):1090-2. doi: 10.1007/BF01367462. PMID: 7780233

Clinical prediction guides

A pulmonary chondromatous hamartoma resembling multiple metastases in the (18)F-FDG PET/CT scan.
Li L, Jiang C, Tian R
Hell J Nucl Med 2016 May-Aug;19(2):176-8. Epub 2016 Jun 22 doi: 10.1967/s002449910376. PMID: 27331216

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