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Postoperative Spindle Cell Nodule of the Bladder

MedGen UID:
277525
•Concept ID:
C1335456
•
Neoplastic Process
Synonyms: Postoperative Spindle Cell Nodule of Bladder; Postoperative Spindle Cell Nodule of the Urinary Bladder; Postoperative Spindle Cell Nodule of Urinary Bladder; Posttraumatic Spindle Cell Nodule of Bladder; Posttraumatic Spindle Cell Nodule of the Bladder; Posttraumatic Spindle Cell Nodule of the Urinary Bladder; Posttraumatic Spindle Cell Nodule of Urinary Bladder

Definition

A benign, reactive lesion of the bladder, occurring status post bladder instrumentation; histologic exam demonstrates a fascicular growth pattern of plump or elongated spindle cells infiltrating the bladder wall without atypia or necrosis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPostoperative Spindle Cell Nodule of the Bladder

Professional guidelines

PubMed

Inflammatory pseudotumor and sarcoma of urinary bladder: differential diagnosis and outcome in thirty-eight spindle cell neoplasms.
Iczkowski KA, Shanks JH, Gadaleanu V, Cheng L, Jones EC, Neumann R, Nascimento AG, Bostwick DG
Mod Pathol 2001 Oct;14(10):1043-51. doi: 10.1038/modpathol.3880434. PMID: 11598176

Recent clinical studies

Etiology

Inflammatory myofibroblastic tumour of the urinary bladder: the role of immunoglobulin G4 and the comparison of two immunohistochemical antibodies and fluorescence in-situ hybridization for the detection of anaplastic lymphoma kinase alterations.
Choi E, Williamson SR, Montironi R, Zhang S, Wang M, Eble JN, Grignon DJ, Lopez-Beltran A, Idrees MT, Baldridge LA, Scarpelli M, Jones CL, Wang L, MacLennan GT, Osunkoya AO, Cheng L
Histopathology 2015 Jul;67(1):20-38. Epub 2015 Jan 29 doi: 10.1111/his.12619. PMID: 25406945
Pseudosarcomatous and sarcomatous proliferations of the bladder.
Spiess PE, Tuziak T, Tibbs RF, Bassett R, Tamboli P, Brown GA, Grossman HB, Ayala AG, Czerniak B
Hum Pathol 2007 May;38(5):753-61. Epub 2007 Feb 15 doi: 10.1016/j.humpath.2006.11.014. PMID: 17306332
Inflammatory pseudotumor and sarcoma of urinary bladder: differential diagnosis and outcome in thirty-eight spindle cell neoplasms.
Iczkowski KA, Shanks JH, Gadaleanu V, Cheng L, Jones EC, Neumann R, Nascimento AG, Bostwick DG
Mod Pathol 2001 Oct;14(10):1043-51. doi: 10.1038/modpathol.3880434. PMID: 11598176
Spindle-cell proliferations of the urinary tract. An immunohistochemical study.
Wick MR, Brown BA, Young RH, Mills SE
Am J Surg Pathol 1988 May;12(5):379-89. doi: 10.1097/00000478-198805000-00006. PMID: 3284397

Diagnosis

Inflammatory myofibroblastic tumor of the bladder.
Alderman M, Kunju LP
Arch Pathol Lab Med 2014 Oct;138(10):1272-7. doi: 10.5858/arpa.2014-0274-CC. PMID: 25268188
Tumor-like lesions of the urinary bladder.
Young RH
Mod Pathol 2009 Jun;22 Suppl 2:S37-52. doi: 10.1038/modpathol.2008.201. PMID: 19494852
Postoperative spindle cell nodule of the prostate and bladder.
Huang WL, Ro JY, Grignon DJ, Swanson D, Ordonez NG, Ayala AG
J Urol 1990 Apr;143(4):824-6. doi: 10.1016/s0022-5347(17)40110-8. PMID: 2313819
Spindle cell lesions of the urinary bladder.
Young RH
Histol Histopathol 1990 Oct;5(4):505-12. PMID: 2134403
Spindle-cell proliferations of the urinary tract. An immunohistochemical study.
Wick MR, Brown BA, Young RH, Mills SE
Am J Surg Pathol 1988 May;12(5):379-89. doi: 10.1097/00000478-198805000-00006. PMID: 3284397

Prognosis

Low-grade myofibroblastic proliferations of the urinary bladder.
Alquati S, Gira FA, Bartoli V, Contini S, Corradi D
Arch Pathol Lab Med 2013 Aug;137(8):1117-28. doi: 10.5858/arpa.2012-0326-RA. PMID: 23899070
Pseudosarcomatous myofibroblastic proliferations of the bladder: a clinicopathologic study of 42 cases.
Harik LR, Merino C, Coindre JM, Amin MB, Pedeutour F, Weiss SW
Am J Surg Pathol 2006 Jul;30(7):787-94. doi: 10.1097/01.pas.0000208903.46354.6f. PMID: 16819319
Inflammatory pseudotumor and sarcoma of urinary bladder: differential diagnosis and outcome in thirty-eight spindle cell neoplasms.
Iczkowski KA, Shanks JH, Gadaleanu V, Cheng L, Jones EC, Neumann R, Nascimento AG, Bostwick DG
Mod Pathol 2001 Oct;14(10):1043-51. doi: 10.1038/modpathol.3880434. PMID: 11598176

Clinical prediction guides

Spindle-cell proliferations of the urinary tract. An immunohistochemical study.
Wick MR, Brown BA, Young RH, Mills SE
Am J Surg Pathol 1988 May;12(5):379-89. doi: 10.1097/00000478-198805000-00006. PMID: 3284397

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