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Endometrial Endometrioid Adenocarcinoma with Clear Cell Change

MedGen UID:
277851
Concept ID:
C1336908
Neoplastic Process

Definition

A morphologic variant of endometrioid adenocarcinoma characterized by the presence of large multinucleated clear cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEndometrial Endometrioid Adenocarcinoma with Clear Cell Change

Professional guidelines

PubMed

Eggink FA, Mom CH, Boll D, Ezendam NPM, Kruitwagen RFPM, Pijnenborg JMA, van der Aa MA, Nijman HW
Gynecol Oncol 2017 Aug;146(2):380-385. Epub 2017 May 25 doi: 10.1016/j.ygyno.2017.05.025. PMID: 28552255

Recent clinical studies

Etiology

Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
J Gynecol Oncol 2023 Sep;34(5):e85. Epub 2023 Aug 8 doi: 10.3802/jgo.2023.34.e85. PMID: 37593813Free PMC Article
Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
Int J Gynaecol Obstet 2023 Aug;162(2):383-394. Epub 2023 Jun 20 doi: 10.1002/ijgo.14923. PMID: 37337978
Plaza-Parrochia F, Romero C, Valladares L, Vega M
Steroids 2017 Oct;126:85-91. Epub 2017 Aug 18 doi: 10.1016/j.steroids.2017.08.007. PMID: 28827068
Mang C, Birkenmaier A, Cathomas G, Humburg J
Arch Gynecol Obstet 2017 Jun;295(6):1435-1440. Epub 2017 Apr 18 doi: 10.1007/s00404-017-4370-4. PMID: 28421274
Ramalingam P
Oncology (Williston Park) 2016 Feb;30(2):166-76. PMID: 26892153

Diagnosis

Lucas E, Carrick KS
Semin Diagn Pathol 2022 May;39(3):159-175. Epub 2022 Feb 11 doi: 10.1053/j.semdp.2022.02.002. PMID: 35397943
Shiozaki T, Miwa M, Sakuma T, Suzuki K, Kogiku A, Yamamoto K, Senda T, Yano H, Kitai M, Matsuoka K, Sudo T, Nagao S, Yamaguchi S
Int J Gynecol Cancer 2019 Jun;29(5):886-889. Epub 2019 Jan 4 doi: 10.1136/ijgc-2018-000041. PMID: 30826751
Plaza-Parrochia F, Romero C, Valladares L, Vega M
Steroids 2017 Oct;126:85-91. Epub 2017 Aug 18 doi: 10.1016/j.steroids.2017.08.007. PMID: 28827068
Ramalingam P
Oncology (Williston Park) 2016 Feb;30(2):166-76. PMID: 26892153
Takeda T, Banno K, Okawa R, Yanokura M, Iijima M, Irie-Kunitomi H, Nakamura K, Iida M, Adachi M, Umene K, Nogami Y, Masuda K, Kobayashi Y, Tominaga E, Aoki D
Oncol Rep 2016 Feb;35(2):607-13. Epub 2015 Nov 16 doi: 10.3892/or.2015.4421. PMID: 26572704Free PMC Article

Therapy

Rottmann D, Snir OL, Wu X, Wong S, Hui P, Santin AD, Buza N
Mod Pathol 2020 Jan;33(1):118-127. Epub 2019 Sep 2 doi: 10.1038/s41379-019-0358-x. PMID: 31477811
Eggink FA, Mom CH, Boll D, Ezendam NPM, Kruitwagen RFPM, Pijnenborg JMA, van der Aa MA, Nijman HW
Gynecol Oncol 2017 Aug;146(2):380-385. Epub 2017 May 25 doi: 10.1016/j.ygyno.2017.05.025. PMID: 28552255
Takeda T, Banno K, Okawa R, Yanokura M, Iijima M, Irie-Kunitomi H, Nakamura K, Iida M, Adachi M, Umene K, Nogami Y, Masuda K, Kobayashi Y, Tominaga E, Aoki D
Oncol Rep 2016 Feb;35(2):607-13. Epub 2015 Nov 16 doi: 10.3892/or.2015.4421. PMID: 26572704Free PMC Article
Blumenfeld Z
Fertil Steril 2004 Mar;81(3):487-92. doi: 10.1016/j.fertnstert.2003.07.038. PMID: 15037387
Dallenbach-Hellweg G, Schmidt D, Hellberg P, Bourne T, Kreuzwieser E, Dören M, Rydh W, Rudenstam G, Granberg S
Arch Gynecol Obstet 2000 Apr;263(4):170-7. doi: 10.1007/s004040050276. PMID: 10834325

Prognosis

Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
J Gynecol Oncol 2023 Sep;34(5):e85. Epub 2023 Aug 8 doi: 10.3802/jgo.2023.34.e85. PMID: 37593813Free PMC Article
Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
Int J Gynaecol Obstet 2023 Aug;162(2):383-394. Epub 2023 Jun 20 doi: 10.1002/ijgo.14923. PMID: 37337978
Mang C, Birkenmaier A, Cathomas G, Humburg J
Arch Gynecol Obstet 2017 Jun;295(6):1435-1440. Epub 2017 Apr 18 doi: 10.1007/s00404-017-4370-4. PMID: 28421274
Ramalingam P
Oncology (Williston Park) 2016 Feb;30(2):166-76. PMID: 26892153
Liu FS
Taiwan J Obstet Gynecol 2007 Mar;46(1):26-32. doi: 10.1016/S1028-4559(08)60102-3. PMID: 17389185

Clinical prediction guides

Fridrichova I, Kalinkova L, Karhanek M, Smolkova B, Machalekova K, Wachsmannova L, Nikolaieva N, Kajo K
Int J Mol Sci 2020 Dec 24;22(1) doi: 10.3390/ijms22010127. PMID: 33374439Free PMC Article
Mang C, Birkenmaier A, Cathomas G, Humburg J
Arch Gynecol Obstet 2017 Jun;295(6):1435-1440. Epub 2017 Apr 18 doi: 10.1007/s00404-017-4370-4. PMID: 28421274
Ramalingam P
Oncology (Williston Park) 2016 Feb;30(2):166-76. PMID: 26892153
Zaino RJ
Int J Gynecol Pathol 2014 Jul;33(4):357-64. doi: 10.1097/PGP.0000000000000137. PMID: 24901395
Liu FS
Taiwan J Obstet Gynecol 2007 Mar;46(1):26-32. doi: 10.1016/S1028-4559(08)60102-3. PMID: 17389185

Supplemental Content

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