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Inadequate Pain Relief

MedGen UID:
310870
•Concept ID:
C1708484
•
Finding

Definition

Continuing discomfort due to a failure of current treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInadequate Pain Relief

Professional guidelines

PubMed

Combining opioids and non-opioids for pain management: Current status.
Li JX
Neuropharmacology 2019 Nov 1;158:107619. Epub 2019 Apr 25 doi: 10.1016/j.neuropharm.2019.04.025. PMID: 31029588
Diagnosis and Management of Vertebral Compression Fractures.
McCarthy J, Davis A
Am Fam Physician 2016 Jul 1;94(1):44-50. PMID: 27386723
Emerging drug targets for pain treatment.
Li JX, Zhang Y
Eur J Pharmacol 2012 Apr 15;681(1-3):1-5. Epub 2012 Jan 31 doi: 10.1016/j.ejphar.2012.01.017. PMID: 22314220

Recent clinical studies

Etiology

Pain in the Ehlers-Danlos syndromes: Mechanisms, models, and challenges.
Malfait F, Colman M, Vroman R, De Wandele I, Rombaut L, Miller RE, Malfait AM, Syx D
Am J Med Genet C Semin Med Genet 2021 Dec;187(4):429-445. Epub 2021 Nov 19 doi: 10.1002/ajmg.c.31950. PMID: 34797601
Congruence between nurses' and patients' assessment of postoperative pain: a literature review.
Wooldridge S, Branney J
Br J Nurs 2020 Feb 27;29(4):212-220. doi: 10.12968/bjon.2020.29.4.212. PMID: 32105527
Diagnosis and Management of Vertebral Compression Fractures.
McCarthy J, Davis A
Am Fam Physician 2016 Jul 1;94(1):44-50. PMID: 27386723
Opioids: a two-faced Janus.
Ahlbeck K
Curr Med Res Opin 2011 Feb;27(2):439-48. Epub 2011 Jan 3 doi: 10.1185/03007995.2010.545379. PMID: 21194392
Inadequate pain relief and consequences in oncological elderly patients.
Caltagirone C, Spoletini I, Gianni W, Spalletta G
Surg Oncol 2010 Sep;19(3):178-83. Epub 2009 Dec 16 doi: 10.1016/j.suronc.2009.11.009. PMID: 20015635

Diagnosis

Dorsal root ganglion stimulation device explantation: A multicenter pooled data analysis.
Chapman KB, Yang A, Mogilner AY, Mandelberg N, Patel KV, Lubenow T, Deer T, Kallewaard JW, van Helmond N
Pain Pract 2022 Jun;22(5):522-531. Epub 2022 May 6 doi: 10.1111/papr.13113. PMID: 35429364
Inadequate pain relief among patients with primary knee osteoarthritis.
Laires PA, Laíns J, Miranda LC, Cernadas R, Rajagopalan S, Taylor SD, Silva JC
Rev Bras Reumatol Engl Ed 2017 May-Jun;57(3):229-237. Epub 2016 Dec 5 doi: 10.1016/j.rbre.2016.11.005. PMID: 28535895
Perioperative Hyperalgesia and Associated Clinical Factors.
Malik OS, Kaye AD, Urman RD
Curr Pain Headache Rep 2017 Jan;21(1):4. doi: 10.1007/s11916-017-0602-3. PMID: 28150135
Diagnosis and Management of Vertebral Compression Fractures.
McCarthy J, Davis A
Am Fam Physician 2016 Jul 1;94(1):44-50. PMID: 27386723
Pharmacogenomics of opioids and perioperative pain management.
Sadhasivam S, Chidambaran V
Pharmacogenomics 2012 Nov;13(15):1719-40. doi: 10.2217/pgs.12.152. PMID: 23171337

Therapy

Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT.
Tesfaye S, Sloan G, Petrie J, White D, Bradburn M, Young T, Rajbhandari S, Sharma S, Rayman G, Gouni R, Alam U, Julious SA, Cooper C, Loban A, Sutherland K, Glover R, Waterhouse S, Turton E, Horspool M, Gandhi R, Maguire D, Jude E, Ahmed SH, Vas P, Hariman C, McDougall C, Devers M, Tsatlidis V, Johnson M, Bouhassira D, Bennett DL, Selvarajah D
Health Technol Assess 2022 Oct;26(39):1-100. doi: 10.3310/RXUO6757. PMID: 36259684Free PMC Article
Post-operative pain after caesarean section.
Bjørnstad J, Ræder J
Tidsskr Nor Laegeforen 2020 May 5;140(7) Epub 2020 May 4 doi: 10.4045/tidsskr.19.0506. PMID: 32378860
Combining opioids and non-opioids for pain management: Current status.
Li JX
Neuropharmacology 2019 Nov 1;158:107619. Epub 2019 Apr 25 doi: 10.1016/j.neuropharm.2019.04.025. PMID: 31029588
Diagnosis and Management of Vertebral Compression Fractures.
McCarthy J, Davis A
Am Fam Physician 2016 Jul 1;94(1):44-50. PMID: 27386723
Opioids: a two-faced Janus.
Ahlbeck K
Curr Med Res Opin 2011 Feb;27(2):439-48. Epub 2011 Jan 3 doi: 10.1185/03007995.2010.545379. PMID: 21194392

Prognosis

Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT.
Tesfaye S, Sloan G, Petrie J, White D, Bradburn M, Young T, Rajbhandari S, Sharma S, Rayman G, Gouni R, Alam U, Julious SA, Cooper C, Loban A, Sutherland K, Glover R, Waterhouse S, Turton E, Horspool M, Gandhi R, Maguire D, Jude E, Ahmed SH, Vas P, Hariman C, McDougall C, Devers M, Tsatlidis V, Johnson M, Bouhassira D, Bennett DL, Selvarajah D
Health Technol Assess 2022 Oct;26(39):1-100. doi: 10.3310/RXUO6757. PMID: 36259684Free PMC Article
Perioperative Hyperalgesia and Associated Clinical Factors.
Malik OS, Kaye AD, Urman RD
Curr Pain Headache Rep 2017 Jan;21(1):4. doi: 10.1007/s11916-017-0602-3. PMID: 28150135
Surgical approaches to chronic pancreatitis: indications and imaging findings.
Hafezi-Nejad N, Singh VK, Johnson SI, Makary MA, Hirose K, Fishman EK, Zaheer A
Abdom Radiol (NY) 2016 Oct;41(10):1980-96. doi: 10.1007/s00261-016-0775-y. PMID: 27207476
Pharmacogenomics of opioids and perioperative pain management.
Sadhasivam S, Chidambaran V
Pharmacogenomics 2012 Nov;13(15):1719-40. doi: 10.2217/pgs.12.152. PMID: 23171337
Current concepts and practice in postoperative pain management: need for a change?
Filos KS, Lehmann KA
Eur Surg Res 1999;31(2):97-107. doi: 10.1159/000008627. PMID: 10213847

Clinical prediction guides

Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT.
Tesfaye S, Sloan G, Petrie J, White D, Bradburn M, Young T, Rajbhandari S, Sharma S, Rayman G, Gouni R, Alam U, Julious SA, Cooper C, Loban A, Sutherland K, Glover R, Waterhouse S, Turton E, Horspool M, Gandhi R, Maguire D, Jude E, Ahmed SH, Vas P, Hariman C, McDougall C, Devers M, Tsatlidis V, Johnson M, Bouhassira D, Bennett DL, Selvarajah D
Health Technol Assess 2022 Oct;26(39):1-100. doi: 10.3310/RXUO6757. PMID: 36259684Free PMC Article
Congruence between nurses' and patients' assessment of postoperative pain: a literature review.
Wooldridge S, Branney J
Br J Nurs 2020 Feb 27;29(4):212-220. doi: 10.12968/bjon.2020.29.4.212. PMID: 32105527
Inadequate pain relief among patients with primary knee osteoarthritis.
Laires PA, Laíns J, Miranda LC, Cernadas R, Rajagopalan S, Taylor SD, Silva JC
Rev Bras Reumatol Engl Ed 2017 May-Jun;57(3):229-237. Epub 2016 Dec 5 doi: 10.1016/j.rbre.2016.11.005. PMID: 28535895
Surgical approaches to chronic pancreatitis: indications and imaging findings.
Hafezi-Nejad N, Singh VK, Johnson SI, Makary MA, Hirose K, Fishman EK, Zaheer A
Abdom Radiol (NY) 2016 Oct;41(10):1980-96. doi: 10.1007/s00261-016-0775-y. PMID: 27207476
Pharmacogenomics of opioids and perioperative pain management.
Sadhasivam S, Chidambaran V
Pharmacogenomics 2012 Nov;13(15):1719-40. doi: 10.2217/pgs.12.152. PMID: 23171337

Recent systematic reviews

Intranasal analgesia for acute moderate to severe pain in children - a systematic review and meta-analysis.
Prescott MG, Iakovleva E, Simpson MR, Pedersen SA, Munblit D, Vallersnes OM, Austad B
BMC Pediatr 2023 Aug 18;23(1):405. doi: 10.1186/s12887-023-04203-x. PMID: 37596559Free PMC Article
Fentanyl for neuropathic pain in adults.
Derry S, Stannard C, Cole P, Wiffen PJ, Knaggs R, Aldington D, Moore RA
Cochrane Database Syst Rev 2016 Oct 11;10(10):CD011605. doi: 10.1002/14651858.CD011605.pub2. PMID: 27727431Free PMC Article
First do no harm: pain relief for the peripheral venous cannulation of adults, a systematic review and network meta-analysis.
Bond M, Crathorne L, Peters J, Coelho H, Haasova M, Cooper C, Milner Q, Shawyer V, Hyde C, Powell R
BMC Anesthesiol 2016 Oct 1;16(1):81. doi: 10.1186/s12871-016-0252-8. PMID: 27716082Free PMC Article
Discontinuation of epidural analgesia late in labour for reducing the adverse delivery outcomes associated with epidural analgesia.
Torvaldsen S, Roberts CL, Bell JC, Raynes-Greenow CH
Cochrane Database Syst Rev 2004 Oct 18;2004(4):CD004457. doi: 10.1002/14651858.CD004457.pub2. PMID: 15495111Free PMC Article
Opioid switching to improve pain relief and drug tolerability.
Quigley C
Cochrane Database Syst Rev 2004;(3):CD004847. doi: 10.1002/14651858.CD004847. PMID: 15266542

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