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Neurological Deficit or Dysfunction

MedGen UID:
311046
•Concept ID:
C1709219
•
Finding

Definition

A finding of pathologic function within the central or peripheral nervous system, secondary to developmental abnormalities, infections, neurologic damage, or tumors. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeurological Deficit or Dysfunction

Professional guidelines

PubMed

Back Pain: Differential Diagnosis and Management.
Gibbs D, McGahan BG, Ropper AE, Xu DS
Neurol Clin 2023 Feb;41(1):61-76. Epub 2022 Oct 29 doi: 10.1016/j.ncl.2022.07.002. PMID: 36400559
Definition and Diagnostic Criteria for Sarcopenic Obesity: ESPEN and EASO Consensus Statement.
Donini LM, Busetto L, Bischoff SC, Cederholm T, Ballesteros-Pomar MD, Batsis JA, Bauer JM, Boirie Y, Cruz-Jentoft AJ, Dicker D, Frara S, Frühbeck G, Genton L, Gepner Y, Giustina A, Gonzalez MC, Han HS, Heymsfield SB, Higashiguchi T, Laviano A, Lenzi A, Nyulasi I, Parrinello E, Poggiogalle E, Prado CM, Salvador J, Rolland Y, Santini F, Serlie MJ, Shi H, Sieber CC, Siervo M, Vettor R, Villareal DT, Volkert D, Yu J, Zamboni M, Barazzoni R
Obes Facts 2022;15(3):321-335. Epub 2022 Feb 23 doi: 10.1159/000521241. PMID: 35196654Free PMC Article
Clinical practice guideline on diagnosis and treatment of hyponatraemia.
Spasovski G, Vanholder R, Allolio B, Annane D, Ball S, Bichet D, Decaux G, Fenske W, Hoorn EJ, Ichai C, Joannidis M, Soupart A, Zietse R, Haller M, van der Veer S, Van Biesen W, Nagler E; Hyponatraemia Guideline Development Group
Eur J Endocrinol 2014 Mar;170(3):G1-47. Epub 2014 Feb 25 doi: 10.1530/EJE-13-1020. PMID: 24569125

Recent clinical studies

Etiology

Persistent neurologic symptoms and cognitive dysfunction in non-hospitalized Covid-19 "long haulers".
Graham EL, Clark JR, Orban ZS, Lim PH, Szymanski AL, Taylor C, DiBiase RM, Jia DT, Balabanov R, Ho SU, Batra A, Liotta EM, Koralnik IJ
Ann Clin Transl Neurol 2021 May;8(5):1073-1085. Epub 2021 Mar 30 doi: 10.1002/acn3.51350. PMID: 33755344Free PMC Article
Scalp-acupuncture for patients with hemiplegic paralysis of acute ischaemic stroke: a randomized controlled clinical trial.
Wang J, Tian L, Zhang Z, Yuan B, Zhang T, Li X, Jiang H, Du X
J Tradit Chin Med 2020 Oct;40(5):845-854. doi: 10.19852/j.cnki.jtcm.2020.05.015. PMID: 33000586
ACR Appropriateness Criteria® Headache.
Expert Panel on Neurologic Imaging, Whitehead MT, Cardenas AM, Corey AS, Policeni B, Burns J, Chakraborty S, Crowley RW, Jabbour P, Ledbetter LN, Lee RK, Pannell JS, Pollock JM, Powers WJ, Setzen G, Shih RY, Subramaniam RM, Utukuri PS, Bykowski J
J Am Coll Radiol 2019 Nov;16(11S):S364-S377. doi: 10.1016/j.jacr.2019.05.030. PMID: 31685104
Diagnosis and clinical evaluation of neurogenic bladder.
Amarenco G, Sheikh Ismaël S, Chesnel C, Charlanes A, LE Breton F
Eur J Phys Rehabil Med 2017 Dec;53(6):975-980. Epub 2017 Oct 25 doi: 10.23736/S1973-9087.17.04992-9. PMID: 29072046
Molecular mechanisms underlying neurodevelopmental disorders, ADHD and autism.
Bădescu GM, Fîlfan M, Sandu RE, Surugiu R, Ciobanu O, Popa-Wagner A
Rom J Morphol Embryol 2016;57(2):361-6. PMID: 27516006

Diagnosis

Persistent neurologic symptoms and cognitive dysfunction in non-hospitalized Covid-19 "long haulers".
Graham EL, Clark JR, Orban ZS, Lim PH, Szymanski AL, Taylor C, DiBiase RM, Jia DT, Balabanov R, Ho SU, Batra A, Liotta EM, Koralnik IJ
Ann Clin Transl Neurol 2021 May;8(5):1073-1085. Epub 2021 Mar 30 doi: 10.1002/acn3.51350. PMID: 33755344Free PMC Article
Persistent idiopathic facial pain.
Benoliel R, Gaul C
Cephalalgia 2017 Jun;37(7):680-691. Epub 2017 Apr 20 doi: 10.1177/0333102417706349. PMID: 28425324
Low Back Pain and Spondylosis.
Elder BD, Witham TF
Semin Neurol 2016 Oct;36(5):456-461. Epub 2016 Sep 23 doi: 10.1055/s-0036-1585071. PMID: 27704501
The diagnosis and treatment of nonspecific neck pain and whiplash.
Binder A
Eura Medicophys 2007 Mar;43(1):79-89. PMID: 17369782
Intracranial hypertension.
Kabat AG
Optom Clin 1996;5(3-4):153-79. PMID: 8972512

Therapy

Impairment-oriented training (IOT)--scientific concept and evidence-based treatment strategies.
Platz T
Restor Neurol Neurosci 2004;22(3-5):301-15. PMID: 15502273
Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee.
Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW
J Rheumatol 1988 Dec;15(12):1833-40. PMID: 3068365
Electroconvulsive therapy in 1985--a review.
Varghese FT, Singh BS
Med J Aust 1985 Sep 2;143(5):192-6. doi: 10.5694/j.1326-5377.1985.tb122912.x. PMID: 2863740
Food additives.
Rowe KS
Aust Paediatr J 1984 Aug;20(3):171-3. doi: 10.1111/j.1440-1754.1984.tb00071.x. PMID: 6391453
Do coronary artery bypass operations prolong life?
Carr KW, Engler RL, Ross J Jr
West J Med 1982 Apr;136(4):295-308. PMID: 7046257Free PMC Article

Prognosis

Sarcopenia and mild kidney dysfunction and risk of all-cause and cause-specific mortality in older adults.
Wu G, Hu Q, Huang Z, Lai Z, Wang X, Cai M, Lin H
Nephrol Dial Transplant 2024 May 31;39(6):989-999. doi: 10.1093/ndt/gfad243. PMID: 37952094
Etiology and prognosis of patients with unexplained syncope and mid-range left ventricular dysfunction.
Francisco-Pascual J, Rodenas-Alesina E, Rivas-Gándara N, Belahnech Y, Olivella San Emeterio A, Pérez-Rodón J, Benito B, Santos-Ortega A, Moya-Mitjans À, Casas G, Cantalapiedra-Romero J, Maldonado J, Ferreira-González I
Heart Rhythm 2021 Apr;18(4):597-604. Epub 2020 Dec 14 doi: 10.1016/j.hrthm.2020.12.009. PMID: 33326869
Effects of sodium thiosulfate versus observation on development of cisplatin-induced hearing loss in children with cancer (ACCL0431): a multicentre, randomised, controlled, open-label, phase 3 trial.
Freyer DR, Chen L, Krailo MD, Knight K, Villaluna D, Bliss B, Pollock BH, Ramdas J, Lange B, Van Hoff D, VanSoelen ML, Wiernikowski J, Neuwelt EA, Sung L
Lancet Oncol 2017 Jan;18(1):63-74. Epub 2016 Dec 1 doi: 10.1016/S1470-2045(16)30625-8. PMID: 27914822Free PMC Article
Generalised musculoskeletal pain syndromes.
Mourão AF, Blyth FM, Branco JC
Best Pract Res Clin Rheumatol 2010 Dec;24(6):829-40. doi: 10.1016/j.berh.2010.10.005. PMID: 21665129
Sydenham's chorea.
Kulkarni ML, Anees S
Indian Pediatr 1996 Feb;33(2):112-5. PMID: 8772928

Clinical prediction guides

Poststroke seizure: optimising its management.
Xu MY
Stroke Vasc Neurol 2019 Mar;4(1):48-56. Epub 2018 Dec 9 doi: 10.1136/svn-2018-000175. PMID: 31105979Free PMC Article
Acute stroke differential diagnosis: Stroke mimics.
Vilela P
Eur J Radiol 2017 Nov;96:133-144. Epub 2017 May 5 doi: 10.1016/j.ejrad.2017.05.008. PMID: 28551302
A review of the measurement of grip strength in clinical and epidemiological studies: towards a standardised approach.
Roberts HC, Denison HJ, Martin HJ, Patel HP, Syddall H, Cooper C, Sayer AA
Age Ageing 2011 Jul;40(4):423-9. Epub 2011 May 30 doi: 10.1093/ageing/afr051. PMID: 21624928
Validation of a new coma scale: The FOUR score.
Wijdicks EF, Bamlet WR, Maramattom BV, Manno EM, McClelland RL
Ann Neurol 2005 Oct;58(4):585-93. doi: 10.1002/ana.20611. PMID: 16178024
The amputee mobility predictor: an instrument to assess determinants of the lower-limb amputee's ability to ambulate.
Gailey RS, Roach KE, Applegate EB, Cho B, Cunniffe B, Licht S, Maguire M, Nash MS
Arch Phys Med Rehabil 2002 May;83(5):613-27. doi: 10.1053/apmr.2002.32309. PMID: 11994800

Recent systematic reviews

The Effectiveness of Neural Mobilization for Neuromusculoskeletal Conditions: A Systematic Review and Meta-analysis.
Basson A, Olivier B, Ellis R, Coppieters M, Stewart A, Mudzi W
J Orthop Sports Phys Ther 2017 Sep;47(9):593-615. Epub 2017 Jul 13 doi: 10.2519/jospt.2017.7117. PMID: 28704626
Structural Changes of Lumbar Muscles in Non-specific Low Back Pain: A Systematic Review.
Goubert D, Oosterwijck JV, Meeus M, Danneels L
Pain Physician 2016 Sep-Oct;19(7):E985-E1000. PMID: 27676689
Vestibular rehabilitation for unilateral peripheral vestibular dysfunction.
McDonnell MN, Hillier SL
Cochrane Database Syst Rev 2015 Jan 13;1:CD005397. doi: 10.1002/14651858.CD005397.pub4. PMID: 25581507
Recommendation for a definition of acute symptomatic seizure.
Beghi E, Carpio A, Forsgren L, Hesdorffer DC, Malmgren K, Sander JW, Tomson T, Hauser WA
Epilepsia 2010 Apr;51(4):671-5. Epub 2009 Sep 3 doi: 10.1111/j.1528-1167.2009.02285.x. PMID: 19732133
Neck pain.
Binder AI
BMJ Clin Evid 2008 Aug 4;2008 PMID: 19445809Free PMC Article

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