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Ovarian Sertoli Cell Tumor

MedGen UID:
311375
Concept ID:
C1519663
Neoplastic Process

Definition

A rare, typically benign ovarian neoplasm composed of Sertoli cells. Patients may present with pseudoprecocity, menometrorrhagia, amenorrhea, hirsutism, and hoarseness. Rarely it may invade the ovarian stroma and extend beyond the ovary. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOvarian Sertoli Cell Tumor

Professional guidelines

PubMed

Han LM, Weiel JJ, Longacre TA, Folkins AK
Adv Anat Pathol 2022 Sep 1;29(5):297-308. Epub 2022 Jul 1 doi: 10.1097/PAP.0000000000000351. PMID: 35778792
Zhao C, Barner R, Vinh TN, McManus K, Dabbs D, Vang R
Int J Gynecol Pathol 2008 Oct;27(4):507-14. doi: 10.1097/PGP.0b013e31817c1b0a. PMID: 18753972
Zhao C, Bratthauer GL, Barner R, Vang R
Int J Gynecol Pathol 2007 Jan;26(1):1-9. doi: 10.1097/01.pgp.0000232026.22861.b5. PMID: 17197889

Recent clinical studies

Etiology

Zhao C, Barner R, Vinh TN, McManus K, Dabbs D, Vang R
Int J Gynecol Pathol 2008 Oct;27(4):507-14. doi: 10.1097/PGP.0b013e31817c1b0a. PMID: 18753972
Zhao C, Bratthauer GL, Barner R, Vang R
Int J Gynecol Pathol 2007 Jan;26(1):1-9. doi: 10.1097/01.pgp.0000232026.22861.b5. PMID: 17197889
Kantelip B, Cloup N, Dechelotte P
Hum Pathol 1986 Jan;17(1):91-4. doi: 10.1016/s0046-8177(86)80161-7. PMID: 3943854

Diagnosis

Bužinskienė D, Šidlovska E, Vilutytė G
Medicina (Kaunas) 2022 Nov 13;58(11) doi: 10.3390/medicina58111638. PMID: 36422177Free PMC Article
Ning Y, Kong F, Cragun JM, Zheng W
Int J Clin Exp Pathol 2013;6(3):516-20. Epub 2013 Feb 15 PMID: 23412916Free PMC Article
Zhao C, Barner R, Vinh TN, McManus K, Dabbs D, Vang R
Int J Gynecol Pathol 2008 Oct;27(4):507-14. doi: 10.1097/PGP.0b013e31817c1b0a. PMID: 18753972
Zhao C, Bratthauer GL, Barner R, Vang R
Am J Surg Pathol 2007 Sep;31(9):1378-86. doi: 10.1097/PAS.0b013e3180339961. PMID: 17721194
Zhao C, Bratthauer GL, Barner R, Vang R
Int J Gynecol Pathol 2007 Jan;26(1):1-9. doi: 10.1097/01.pgp.0000232026.22861.b5. PMID: 17197889

Prognosis

Bužinskienė D, Šidlovska E, Vilutytė G
Medicina (Kaunas) 2022 Nov 13;58(11) doi: 10.3390/medicina58111638. PMID: 36422177Free PMC Article
Zhao C, Bratthauer GL, Barner R, Vang R
Am J Surg Pathol 2007 Sep;31(9):1378-86. doi: 10.1097/PAS.0b013e3180339961. PMID: 17721194

Clinical prediction guides

Zhao C, Barner R, Vinh TN, McManus K, Dabbs D, Vang R
Int J Gynecol Pathol 2008 Oct;27(4):507-14. doi: 10.1097/PGP.0b013e31817c1b0a. PMID: 18753972
Zhao C, Bratthauer GL, Barner R, Vang R
Am J Surg Pathol 2007 Sep;31(9):1378-86. doi: 10.1097/PAS.0b013e3180339961. PMID: 17721194
Zhao C, Bratthauer GL, Barner R, Vang R
Am J Surg Pathol 2007 Feb;31(2):255-66. doi: 10.1097/01.pas.0000213355.72638.f4. PMID: 17255771
Zhao C, Bratthauer GL, Barner R, Vang R
Int J Gynecol Pathol 2007 Jan;26(1):1-9. doi: 10.1097/01.pgp.0000232026.22861.b5. PMID: 17197889
Pejovic T, Heim S, Alm P, Iosif S, Himmelmann A, Skjaerris J, Mitelman F
Cancer Genet Cytogenet 1993 Jan;65(1):79-80. doi: 10.1016/0165-4608(93)90065-t. PMID: 8431922

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