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Dislocation of the hip-dysmorphism syndrome

MedGen UID:
316970
Concept ID:
C1832353
Disease or Syndrome
Synonym: Dislocation of hip, congenital, with hyperextensibility of fingers and facial dysmorphism
 
Monarch Initiative: MONDO:0011081
OMIM®: 601450
Orphanet: ORPHA2412

Definition

Dislocation of the hip-dysmorphism syndrome is a rare multiple congenital anomalies syndrome characterized by bilateral congenital dislocation of the hip, characteristic facial features (flat mid-face, hypertelorism, epicanthus, puffiness around the eyes, broad nasal bridge, carp-shaped mouth), and joint hyperextensibility. Congenital heart defects, congenital dislocation of the knee, congenital inguinal hernia, and vesicoureteric reflux have also been reported. There have been no further descriptions in the literature since 1995. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDislocation of the hip-dysmorphism syndrome
Follow this link to review classifications for Dislocation of the hip-dysmorphism syndrome in Orphanet.

Professional guidelines

PubMed

Mthethwa J, Chikate A
Musculoskelet Surg 2018 Aug;102(2):119-127. Epub 2017 Oct 17 doi: 10.1007/s12306-017-0514-8. PMID: 29043562
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Am J Med Genet C Semin Med Genet 2017 Mar;175(1):212-219. Epub 2017 Feb 10 doi: 10.1002/ajmg.c.31554. PMID: 28186390
Schiffman E, Ohrbach R, Truelove E, Look J, Anderson G, Goulet JP, List T, Svensson P, Gonzalez Y, Lobbezoo F, Michelotti A, Brooks SL, Ceusters W, Drangsholt M, Ettlin D, Gaul C, Goldberg LJ, Haythornthwaite JA, Hollender L, Jensen R, John MT, De Laat A, de Leeuw R, Maixner W, van der Meulen M, Murray GM, Nixdorf DR, Palla S, Petersson A, Pionchon P, Smith B, Visscher CM, Zakrzewska J, Dworkin SF; International RDC/TMD Consortium Network, International association for Dental Research; Orofacial Pain Special Interest Group, International Association for the Study of Pain
J Oral Facial Pain Headache 2014 Winter;28(1):6-27. doi: 10.11607/jop.1151. PMID: 24482784Free PMC Article

Recent clinical studies

Etiology

Chona DV, Minetos PD, LaPrade CM, Cinque ME, Abrams GD, Sherman SL, Safran MR
Am J Sports Med 2022 Aug;50(10):2834-2841. Epub 2021 Oct 8 doi: 10.1177/03635465211036104. PMID: 34623933
Mavrogenis AF, Panagopoulos GN, Kokkalis ZT, Koulouvaris P, Megaloikonomos PD, Igoumenou V, Mantas G, Moulakakis KG, Sfyroeras GS, Lazaris A, Soucacos PN
Orthopedics 2016 Jul 1;39(4):249-59. Epub 2016 Jun 20 doi: 10.3928/01477447-20160610-06. PMID: 27322172
Schiffman E, Ohrbach R, Truelove E, Look J, Anderson G, Goulet JP, List T, Svensson P, Gonzalez Y, Lobbezoo F, Michelotti A, Brooks SL, Ceusters W, Drangsholt M, Ettlin D, Gaul C, Goldberg LJ, Haythornthwaite JA, Hollender L, Jensen R, John MT, De Laat A, de Leeuw R, Maixner W, van der Meulen M, Murray GM, Nixdorf DR, Palla S, Petersson A, Pionchon P, Smith B, Visscher CM, Zakrzewska J, Dworkin SF; International RDC/TMD Consortium Network, International association for Dental Research; Orofacial Pain Special Interest Group, International Association for the Study of Pain
J Oral Facial Pain Headache 2014 Winter;28(1):6-27. doi: 10.11607/jop.1151. PMID: 24482784Free PMC Article
Craane B, Dijkstra PU, Stappaerts K, De Laat A
J Dent Res 2012 Apr;91(4):364-9. Epub 2012 Feb 8 doi: 10.1177/0022034512438275. PMID: 22318373
Dupuis CS, Westra SJ, Makris J, Wallace EC
Radiographics 2009 May-Jun;29(3):877-86. doi: 10.1148/rg.293085163. PMID: 19448122

Diagnosis

Chaturvedi A, Mann L, Cain U, Chaturvedi A, Klionsky NB
Radiographics 2020 May-Jun;40(3):754-774. Epub 2020 Apr 3 doi: 10.1148/rg.2020190154. PMID: 32243231
Gutiérrez-González LA
Clin Rheumatol 2015 Dec;34(12):2011-9. Epub 2015 Jun 24 doi: 10.1007/s10067-015-2994-y. PMID: 26099604Free PMC Article
Rammelt S, Goronzy J
Foot Ankle Clin 2015 Jun;20(2):253-64. Epub 2015 Mar 29 doi: 10.1016/j.fcl.2015.02.008. PMID: 26043242
Stanbury SJ, Elfar JC
J Am Acad Orthop Surg 2011 Sep;19(9):554-62. doi: 10.5435/00124635-201109000-00006. PMID: 21885701
Wolf JM, Cameron KL, Owens BD
J Am Acad Orthop Surg 2011 Aug;19(8):463-71. doi: 10.5435/00124635-201108000-00002. PMID: 21807914

Therapy

Hopewell S, Keene DJ, Marian IR, Dritsaki M, Heine P, Cureton L, Dutton SJ, Dakin H, Carr A, Hamilton W, Hansen Z, Jaggi A, Littlewood C, Barker KL, Gray A, Lamb SE; GRASP Trial Group
Lancet 2021 Jul 31;398(10298):416-428. Epub 2021 Jul 12 doi: 10.1016/S0140-6736(21)00846-1. PMID: 34265255Free PMC Article
Serrera-Figallo MA, Ruiz-de-León-Hernández G, Torres-Lagares D, Castro-Araya A, Torres-Ferrerosa O, Hernández-Pacheco E, Gutierrez-Perez JL
Toxins (Basel) 2020 Feb 11;12(2) doi: 10.3390/toxins12020112. PMID: 32053883Free PMC Article
Putman S, Boureau F, Girard J, Migaud H, Pasquier G
Orthop Traumatol Surg Res 2019 Feb;105(1S):S43-S51. Epub 2018 Jul 7 doi: 10.1016/j.otsr.2018.04.028. PMID: 29990602
Mthethwa J, Chikate A
Musculoskelet Surg 2018 Aug;102(2):119-127. Epub 2017 Oct 17 doi: 10.1007/s12306-017-0514-8. PMID: 29043562
Judge DP, Dietz HC
Lancet 2005 Dec 3;366(9501):1965-76. doi: 10.1016/S0140-6736(05)67789-6. PMID: 16325700Free PMC Article

Prognosis

Armonaite L, Behndig A
Acta Ophthalmol 2021 Feb;99(1):69-74. Epub 2020 Jun 8 doi: 10.1111/aos.14477. PMID: 32511897
Matthewson G, Kwapisz A, Sasyniuk T, MacDonald P
Clin Sports Med 2019 Apr;38(2):199-213. doi: 10.1016/j.csm.2018.11.001. PMID: 30878044
Mthethwa J, Chikate A
Musculoskelet Surg 2018 Aug;102(2):119-127. Epub 2017 Oct 17 doi: 10.1007/s12306-017-0514-8. PMID: 29043562
Rammelt S, Goronzy J
Foot Ankle Clin 2015 Jun;20(2):253-64. Epub 2015 Mar 29 doi: 10.1016/j.fcl.2015.02.008. PMID: 26043242
Craane B, Dijkstra PU, Stappaerts K, De Laat A
J Dent Res 2012 Apr;91(4):364-9. Epub 2012 Feb 8 doi: 10.1177/0022034512438275. PMID: 22318373

Clinical prediction guides

da Fonseca JO, de Oliveira Vianna RA, Carvalho FR, Velarde LGC, de Oliveira SA, Cardoso CAA, Gameiro VS
J Pediatr 2023 May;256:27-32. Epub 2022 Dec 5 doi: 10.1016/j.jpeds.2022.11.035. PMID: 36470461
Armonaite L, Behndig A
Acta Ophthalmol 2021 Feb;99(1):69-74. Epub 2020 Jun 8 doi: 10.1111/aos.14477. PMID: 32511897
de Carvalho M, Swash M
Handb Clin Neurol 2014;119:435-48. doi: 10.1016/B978-0-7020-4086-3.00028-X. PMID: 24365311
Kibler WB, Ludewig PM, McClure PW, Michener LA, Bak K, Sciascia AD
Br J Sports Med 2013 Sep;47(14):877-85. Epub 2013 Apr 11 doi: 10.1136/bjsports-2013-092425. PMID: 23580420
Wetzel FT, La Rocca H
Clin Orthop Relat Res 1989 Mar;(240):141-52. PMID: 2645074

Recent systematic reviews

De Feyter S, Beyens A, Callewaert B
J Inherit Metab Dis 2023 Mar;46(2):163-173. Epub 2023 Feb 3 doi: 10.1002/jimd.12590. PMID: 36692329
Martín-Martín M, Cortés-Martín J, Tovar-Gálvez MI, Sánchez-García JC, Díaz-Rodríguez L, Rodríguez-Blanque R
Int J Environ Res Public Health 2022 Feb 7;19(3) doi: 10.3390/ijerph19031870. PMID: 35162892Free PMC Article
Chona DV, Minetos PD, LaPrade CM, Cinque ME, Abrams GD, Sherman SL, Safran MR
Am J Sports Med 2022 Aug;50(10):2834-2841. Epub 2021 Oct 8 doi: 10.1177/03635465211036104. PMID: 34623933
Rivière C, Lazennec JY, Van Der Straeten C, Auvinet E, Cobb J, Muirhead-Allwood S
Orthop Traumatol Surg Res 2017 Jun;103(4):559-568. Epub 2017 Apr 1 doi: 10.1016/j.otsr.2017.02.014. PMID: 28373138
van Sleuwen BE, Engelberts AC, Boere-Boonekamp MM, Kuis W, Schulpen TW, L'Hoir MP
Pediatrics 2007 Oct;120(4):e1097-106. doi: 10.1542/peds.2006-2083. PMID: 17908730

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