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Capsular Contracture

MedGen UID:
317484
•Concept ID:
C1707264
•
Finding

Definition

The tightening of scar tissue that forms around the implant. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCapsular Contracture

Professional guidelines

PubMed

Postirradiation Capsular Contracture in Implant-Based Breast Reconstruction: Management and Outcome.
Haran O, Bracha G, Tiosano A, Menes T, Madah E, Gur E, Barnea Y, Arad E
Plast Reconstr Surg 2021 Jan 1;147(1):11-19. doi: 10.1097/PRS.0000000000007453. PMID: 33002986
Surgical Treatment for Capsular Contracture: A New Paradigm and Algorithm.
Hidalgo DA, Weinstein AL
Plast Reconstr Surg 2020 Sep;146(3):516-525. doi: 10.1097/PRS.0000000000007079. PMID: 32842102
Posterior Glenohumeral Instability: Diagnosis and Management.
Sheean AJ, Arner JW, Bradley JP
Arthroscopy 2020 Oct;36(10):2580-2582. Epub 2020 May 20 doi: 10.1016/j.arthro.2020.05.018. PMID: 32442706

Recent clinical studies

Etiology

Incision and Capsular Contracture Risk: Is There a Relationship in Breast Augmentation and Augmentation/Mastopexy?
Swanson E
Ann Plast Surg 2023 Apr 1;90(4):389-391. Epub 2023 Feb 15 doi: 10.1097/SAP.0000000000003437. PMID: 37093773Free PMC Article
Histological Analyses of Capsular Contracture and Associated Risk Factors: A Systematic Review.
Larsen A, Rasmussen LE, Rasmussen LF, Weltz TK, Hemmingsen MN, Poulsen SS, Jacobsen JCB, Vester-Glowinski P, Herly M
Aesthetic Plast Surg 2021 Dec;45(6):2714-2728. Epub 2021 Jul 26 doi: 10.1007/s00266-021-02473-3. PMID: 34312696
Postirradiation Capsular Contracture in Implant-Based Breast Reconstruction: Management and Outcome.
Haran O, Bracha G, Tiosano A, Menes T, Madah E, Gur E, Barnea Y, Arad E
Plast Reconstr Surg 2021 Jan 1;147(1):11-19. doi: 10.1097/PRS.0000000000007453. PMID: 33002986
Epidemiology and Prevention of Breast Prosthesis Capsular Contracture Recurrence.
Ganon S, Morinet S, Serror K, Mimoun M, Chaouat M, Boccara D
Aesthetic Plast Surg 2021 Feb;45(1):15-23. Epub 2020 Jul 21 doi: 10.1007/s00266-020-01876-y. PMID: 32696162
Silicone and autoimmunity.
Hajdu SD, Agmon-Levin N, Shoenfeld Y
Eur J Clin Invest 2011 Feb;41(2):203-11. Epub 2010 Sep 29 doi: 10.1111/j.1365-2362.2010.02389.x. PMID: 20880074

Diagnosis

Exhaustive diagnosis of breast implants with capsular contracture: The microbiology laboratory as a major support.
Castellano M, Marín M, Alcalá L, Cunnas I, Rodríguez B, Ruíz MJ, Lasso J, Pérez-Cano R, Bouza E, Muñoz P, Guembe M
J Plast Reconstr Aesthet Surg 2022 Sep;75(9):3085-3093. Epub 2022 Jun 17 doi: 10.1016/j.bjps.2022.06.014. PMID: 35872019
Management of Symptomatic Patients with Textured Implants.
Asaad M, Offodile AC, Santanelli Di Pompeo F, Bevers TB, Stelly S, Carew LA, Barnea Y, Miranda RN, Butler CE, Clemens MW
Plast Reconstr Surg 2021 May 1;147(5S):58S-68S. doi: 10.1097/PRS.0000000000008047. PMID: 33890882
Posterior Glenohumeral Instability: Diagnosis and Management.
Sheean AJ, Arner JW, Bradley JP
Arthroscopy 2020 Oct;36(10):2580-2582. Epub 2020 May 20 doi: 10.1016/j.arthro.2020.05.018. PMID: 32442706
The Relationship of Bacterial Biofilms and Capsular Contracture in Breast Implants.
Ajdic D, Zoghbi Y, Gerth D, Panthaki ZJ, Thaller S
Aesthet Surg J 2016 Mar;36(3):297-309. Epub 2016 Feb 2 doi: 10.1093/asj/sjv177. PMID: 26843099Free PMC Article
Frozen shoulder.
Robinson CM, Seah KT, Chee YH, Hindle P, Murray IR
J Bone Joint Surg Br 2012 Jan;94(1):1-9. doi: 10.1302/0301-620X.94B1.27093. PMID: 22219239

Therapy

Incision and Capsular Contracture Risk: Is There a Relationship in Breast Augmentation and Augmentation/Mastopexy?
Swanson E
Ann Plast Surg 2023 Apr 1;90(4):389-391. Epub 2023 Feb 15 doi: 10.1097/SAP.0000000000003437. PMID: 37093773Free PMC Article
Histological Analyses of Capsular Contracture and Associated Risk Factors: A Systematic Review.
Larsen A, Rasmussen LE, Rasmussen LF, Weltz TK, Hemmingsen MN, Poulsen SS, Jacobsen JCB, Vester-Glowinski P, Herly M
Aesthetic Plast Surg 2021 Dec;45(6):2714-2728. Epub 2021 Jul 26 doi: 10.1007/s00266-021-02473-3. PMID: 34312696
Capsular contracture in patients with prior breast augmentation undergoing breast conserving therapy and irradiation.
Serritzlev MS, Lorentzen AK, Matthiessen LW, Hölmich LR
J Plast Surg Hand Surg 2020 Aug;54(4):225-232. Epub 2020 May 7 doi: 10.1080/2000656X.2020.1755299. PMID: 32375532
Breast augmentation.
Hidalgo DA, Spector JA
Plast Reconstr Surg 2014 Apr;133(4):567e-583e. doi: 10.1097/PRS.0000000000000033. PMID: 24675209
Silicone and autoimmunity.
Hajdu SD, Agmon-Levin N, Shoenfeld Y
Eur J Clin Invest 2011 Feb;41(2):203-11. Epub 2010 Sep 29 doi: 10.1111/j.1365-2362.2010.02389.x. PMID: 20880074

Prognosis

Postirradiation Capsular Contracture in Implant-Based Breast Reconstruction: Management and Outcome.
Haran O, Bracha G, Tiosano A, Menes T, Madah E, Gur E, Barnea Y, Arad E
Plast Reconstr Surg 2021 Jan 1;147(1):11-19. doi: 10.1097/PRS.0000000000007453. PMID: 33002986
Epidemiology and Prevention of Breast Prosthesis Capsular Contracture Recurrence.
Ganon S, Morinet S, Serror K, Mimoun M, Chaouat M, Boccara D
Aesthetic Plast Surg 2021 Feb;45(1):15-23. Epub 2020 Jul 21 doi: 10.1007/s00266-020-01876-y. PMID: 32696162
Capsular contracture in patients with prior breast augmentation undergoing breast conserving therapy and irradiation.
Serritzlev MS, Lorentzen AK, Matthiessen LW, Hölmich LR
J Plast Surg Hand Surg 2020 Aug;54(4):225-232. Epub 2020 May 7 doi: 10.1080/2000656X.2020.1755299. PMID: 32375532
Frozen shoulder.
Robinson CM, Seah KT, Chee YH, Hindle P, Murray IR
J Bone Joint Surg Br 2012 Jan;94(1):1-9. doi: 10.1302/0301-620X.94B1.27093. PMID: 22219239
Silicone and autoimmunity.
Hajdu SD, Agmon-Levin N, Shoenfeld Y
Eur J Clin Invest 2011 Feb;41(2):203-11. Epub 2010 Sep 29 doi: 10.1111/j.1365-2362.2010.02389.x. PMID: 20880074

Clinical prediction guides

Reduced capsular contracture with smooth and textured breast implants following submuscular mammoplasty: systematic literature review.
Zhu L, Zhu J, Qian Y, Jiang H
Future Oncol 2021 Dec;17(36):5177-5187. Epub 2021 Nov 3 doi: 10.2217/fon-2021-0510. PMID: 34730405
Management of Symptomatic Patients with Textured Implants.
Asaad M, Offodile AC, Santanelli Di Pompeo F, Bevers TB, Stelly S, Carew LA, Barnea Y, Miranda RN, Butler CE, Clemens MW
Plast Reconstr Surg 2021 May 1;147(5S):58S-68S. doi: 10.1097/PRS.0000000000008047. PMID: 33890882
Autologous Fat Grafting and the Occurrence of Radiation-Induced Capsular Contracture.
Martin S, Cai L, Beniwal A, Tevlin R, Lee G, Nazerali RS
Ann Plast Surg 2021 May 1;86(5S Suppl 3):S414-S417. doi: 10.1097/SAP.0000000000002817. PMID: 33833172
Capsular contracture in patients with prior breast augmentation undergoing breast conserving therapy and irradiation.
Serritzlev MS, Lorentzen AK, Matthiessen LW, Hölmich LR
J Plast Surg Hand Surg 2020 Aug;54(4):225-232. Epub 2020 May 7 doi: 10.1080/2000656X.2020.1755299. PMID: 32375532
Silicone and autoimmunity.
Hajdu SD, Agmon-Levin N, Shoenfeld Y
Eur J Clin Invest 2011 Feb;41(2):203-11. Epub 2010 Sep 29 doi: 10.1111/j.1365-2362.2010.02389.x. PMID: 20880074

Recent systematic reviews

Efficacy of Acellular Dermal Matrix Type in Treatment of Capsular Contracture in Breast Augmentation: A Systematic Review and Meta-Analysis.
Samuels K, Millet E, Wong L
Aesthet Surg J 2023 Dec 14;44(1):26-35. doi: 10.1093/asj/sjad265. PMID: 37595294
Reduced capsular contracture with smooth and textured breast implants following submuscular mammoplasty: systematic literature review.
Zhu L, Zhu J, Qian Y, Jiang H
Future Oncol 2021 Dec;17(36):5177-5187. Epub 2021 Nov 3 doi: 10.2217/fon-2021-0510. PMID: 34730405
Histological Analyses of Capsular Contracture and Associated Risk Factors: A Systematic Review.
Larsen A, Rasmussen LE, Rasmussen LF, Weltz TK, Hemmingsen MN, Poulsen SS, Jacobsen JCB, Vester-Glowinski P, Herly M
Aesthetic Plast Surg 2021 Dec;45(6):2714-2728. Epub 2021 Jul 26 doi: 10.1007/s00266-021-02473-3. PMID: 34312696
Examining the Role of Antimicrobial Irrigation and Capsular Contracture: A Systematic Review and Meta-analysis.
Drinane JJ, Chowdhry T, Pham TH, Ritter E
Ann Plast Surg 2017 Jul;79(1):107-114. doi: 10.1097/SAP.0000000000001134. PMID: 28542075
Revisiting the Management of Capsular Contracture in Breast Augmentation: A Systematic Review.
Wan D, Rohrich RJ
Plast Reconstr Surg 2016 Mar;137(3):826-841. doi: 10.1097/01.prs.0000480095.23356.ae. PMID: 26910663

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