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Central nervous system hibernoma

MedGen UID:
317749
•Concept ID:
C1708362
•
Neoplastic Process
Synonyms: Central Nervous System Hibernoma; central nervous system hibernoma; Hibernoma of Central Nervous System; hibernoma of central nervous system; hibernoma of nervous system; Hibernoma of the Central Nervous System; hibernoma of the central nervous system; nervous system hibernoma
 
Monarch Initiative: MONDO:0003943

Definition

A central nervous system benign and slow growing adipose tissue tumor characterized by the presence of polygonal brown fat cells with abundant cytoplasm. [from NCI]

Professional guidelines

PubMed

Abnormalities of the corpus callosum. Can prenatal imaging predict the genetic status? Correlations between imaging phenotype and genotype.
Nguyen T, Heide S, Guilbaud L, Valence S, Perre SV, Blondiaux E, Keren B, Quenum-Miraillet G, Jouannic JM, Mandelbrot L, Picone O, Guet A, Tsatsaris V, Milh M, Girard N, Vincent M, Nizon M, Poirsier C, Vivanti A, Benachi A, Portes VD, Guibaud L, Patat O, Spentchian M, Frugère L, Héron D, Garel C
Prenat Diagn 2023 Jun;43(6):746-755. Epub 2023 May 23 doi: 10.1002/pd.6382. PMID: 37173814
Tumors masquerading as neurological diseases: A caution for clinicians in planning diagnosis and treatment.
Vidhya Annapoorni CS, Retnaswami CS, Mailankody P, Katragadda P, Pillai SK, Rangarajan A, Padmanabha H, Pendharkar H
Neurol India 2020 Mar-Apr;68(2):368-372. doi: 10.4103/0028-3886.280647. PMID: 32415012
Closed spinal dysraphism: a review on diagnosis and treatment in infancy.
Cornette L, Verpoorten C, Lagae L, Plets C, Van Calenbergh F, Casaer P
Eur J Paediatr Neurol 1998;2(4):179-85. doi: 10.1016/s1090-3798(98)80017-2. PMID: 10726589

Recent clinical studies

Etiology

Bladder lipoma: Moroccan case report.
Jendouzi O, Boukhlifi Y, Houadfi OE, Essaoudi MA, Alami M, Ameur A
Pan Afr Med J 2020;37:380. Epub 2020 Dec 29 doi: 10.11604/pamj.2020.37.380.25672. PMID: 33796193Free PMC Article
Congenital Spinal Lipomatous Malformations. Part 1. Spinal Lipomas, Lipomyeloceles, and Lipomyelomeningoceles.
Rhodes RH
Fetal Pediatr Pathol 2020 Jun;39(3):194-245. Epub 2019 Jul 25 doi: 10.1080/15513815.2019.1641859. PMID: 31342816
Concepts in the neurosurgical care of patients with spinal neural tube defects: An embryologic approach.
Blount JP, George TM, Koueik J, Iskandar BJ
Birth Defects Res 2019 Nov 15;111(19):1564-1576. Epub 2019 Oct 2 doi: 10.1002/bdr2.1588. PMID: 31576681
MORPHOLOGICAL PATTERN AND FREQUENCY OF CENTRAL NERVOUS SYSTEM TUMOURS IN CHILDREN.
Bilqees F, Samina K, Mohammad T, Khaleeq-uz-Zamaan
J Ayub Med Coll Abbottabad 2016 Jan-Mar;28(1):44-6. PMID: 27323560
Complex forms of spinal dysraphism.
Patnaik A, Mahapatra AK
Childs Nerv Syst 2013 Sep;29(9):1527-32. Epub 2013 Sep 7 doi: 10.1007/s00381-013-2161-1. PMID: 24013322

Diagnosis

Lateral ventricular liponeurocytoma: Review of literature and case illustration.
Al-Umran MR, Al-Umran SR, Arab AF, Dababo MA, Alotaibi FA
Neurochirurgie 2021 Nov;67(6):579-586. Epub 2021 Mar 22 doi: 10.1016/j.neuchi.2021.03.004. PMID: 33766564
Bladder lipoma: Moroccan case report.
Jendouzi O, Boukhlifi Y, Houadfi OE, Essaoudi MA, Alami M, Ameur A
Pan Afr Med J 2020;37:380. Epub 2020 Dec 29 doi: 10.11604/pamj.2020.37.380.25672. PMID: 33796193Free PMC Article
Pai syndrome: a review.
Olivero F, Foiadelli T, Luzzi S, Marseglia GL, Savasta S
Childs Nerv Syst 2020 Nov;36(11):2635-2640. Epub 2020 Jul 10 doi: 10.1007/s00381-020-04788-z. PMID: 32651596Free PMC Article
Liponeurocytoma of the Cerebellopontine Angle.
Chiaramonte C, Rabaste S, Jacquesson T, Meyronet D, Cotton F, Jouanneau E, Berhouma M
World Neurosurg 2018 Apr;112:18-24. Epub 2018 Jan 8 doi: 10.1016/j.wneu.2018.01.012. PMID: 29325939
CLOVE Syndrome.
Kasinathan A, Sankhyan N, Ahuja CK, Singhi P
Indian J Pediatr 2018 Jan;85(1):79-80. Epub 2017 Jul 28 doi: 10.1007/s12098-017-2416-z. PMID: 28752282

Therapy

Encephalocraniocutaneous lipomatosis: A case report with review of literature.
Siddiqui S, Naaz S, Ahmad M, Khan ZA, Wahab S, Rashid BA
Neuroradiol J 2017 Dec;30(6):578-582. Epub 2017 Jul 14 doi: 10.1177/1971400917693638. PMID: 28707961Free PMC Article
Corpus callosum lipoma.
Rajan DS, Popescu A
Neurology 2012 Apr 24;78(17):1366. doi: 10.1212/WNL.0b013e318251838b. PMID: 22529205
Surveillance of adverse effects during a vaccination campaign against meningitis C.
Laribière A, Miremont-Salamé G, Reyre H, Abouelfath A, Liège L, Moore N, Haramburu F
Eur J Clin Pharmacol 2005 Dec;61(12):907-11. Epub 2005 Nov 18 doi: 10.1007/s00228-005-0053-3. PMID: 16328316
US of the spinal cord in newborns: spectrum of normal findings, variants, congenital anomalies, and acquired diseases.
Unsinn KM, Geley T, Freund MC, Gassner I
Radiographics 2000 Jul-Aug;20(4):923-38. doi: 10.1148/radiographics.20.4.g00jl06923. PMID: 10903684
The biological resolution of malformations of the central nervous system.
McLone DG
Neurosurgery 1998 Dec;43(6):1375-80; discussion 1380-1. doi: 10.1097/00006123-199812000-00071. PMID: 9848852

Prognosis

Bladder lipoma: Moroccan case report.
Jendouzi O, Boukhlifi Y, Houadfi OE, Essaoudi MA, Alami M, Ameur A
Pan Afr Med J 2020;37:380. Epub 2020 Dec 29 doi: 10.11604/pamj.2020.37.380.25672. PMID: 33796193Free PMC Article
Liponeurocytoma of the Cerebellopontine Angle.
Chiaramonte C, Rabaste S, Jacquesson T, Meyronet D, Cotton F, Jouanneau E, Berhouma M
World Neurosurg 2018 Apr;112:18-24. Epub 2018 Jan 8 doi: 10.1016/j.wneu.2018.01.012. PMID: 29325939
MORPHOLOGICAL PATTERN AND FREQUENCY OF CENTRAL NERVOUS SYSTEM TUMOURS IN CHILDREN.
Bilqees F, Samina K, Mohammad T, Khaleeq-uz-Zamaan
J Ayub Med Coll Abbottabad 2016 Jan-Mar;28(1):44-6. PMID: 27323560
Incidental findings on brain and spine imaging in children.
Maher CO, Piatt JH Jr; Section on Neurologic Surgery, American Academy of Pediatrics
Pediatrics 2015 Apr;135(4):e1084-96. doi: 10.1542/peds.2015-0071. PMID: 25825535
Central liponeurocytoma.
George DH, Scheithauer BW
Am J Surg Pathol 2001 Dec;25(12):1551-5. doi: 10.1097/00000478-200112000-00013. PMID: 11717547

Clinical prediction guides

Corpus Callosum Lipomas in Children.
Gezer B, Karabagli H, Koktekir E, Sahinoglu M, Karabagli P
Turk Neurosurg 2020;30(4):573-576. doi: 10.5137/1019-5149.JTN.27692-19.6. PMID: 32530476
Central liponeurocytoma as a clinical entity.
Börekci A, Kuru Bektaşoğlu P, Ramazanoğlu AF, Gürer B, Çelikoğlu E
Neurol Neurochir Pol 2018 Nov-Dec;52(6):670-676. Epub 2018 Sep 11 doi: 10.1016/j.pjnns.2018.09.001. PMID: 30219587
Intracranial lipomas: clinical and imaging findings.
Karakaş E, Doğan MS, Çullu N, Kocatürk M, Kocatürk Ö, Karakaş Ö, Celik B, Boyaci FN
Clin Ter 2014;165(2):e134-8. doi: 10.7471/CT.2014.1696. PMID: 24770821
Intracranial lipomas: clinical appearances on neuroimaging and clinical significance.
Jabot G, Stoquart-Elsankari S, Saliou G, Toussaint P, Deramond H, Lehmann P
J Neurol 2009 Jun;256(6):851-5. Epub 2009 Mar 12 doi: 10.1007/s00415-009-5087-5. PMID: 19280105
Magnetic resonance imaging (MRI): method and early clinical experiences in diseases of the central nervous system.
Huk WJ, Gademann G
Neurosurg Rev 1984;7(4):259-80. doi: 10.1007/BF01892907. PMID: 6397697

Recent systematic reviews

Diprosopus: A Rare Case of Craniofacial Duplication and a Systematic Review of the Literature.
Trevisani V, Balestri E, Napoli M, Caraffi SG, Baroni MC, Peluso F, Colonna A, Iughetti L, Gargano G, Superti-Furga A, Garavelli L
Genes (Basel) 2023 Aug 31;14(9) doi: 10.3390/genes14091745. PMID: 37761885Free PMC Article
Lateral ventricular liponeurocytoma: Review of literature and case illustration.
Al-Umran MR, Al-Umran SR, Arab AF, Dababo MA, Alotaibi FA
Neurochirurgie 2021 Nov;67(6):579-586. Epub 2021 Mar 22 doi: 10.1016/j.neuchi.2021.03.004. PMID: 33766564
Cerebellopontine Angle and Internal Auditory Canal Lipomas: Case Series and Systematic Review.
Totten DJ, Manzoor NF, Perkins EL, Labadie RF, Bennett ML, Haynes DS
Laryngoscope 2021 Sep;131(9):2081-2087. Epub 2021 Feb 10 doi: 10.1002/lary.29434. PMID: 33567134
Liponeurocytoma: Systematic Review of a Rare Entity.
Gembruch O, Junker A, Mönninghoff C, Ahmadipour Y, Darkwah Oppong M, Sure U, El Hindy N, Lemonas E
World Neurosurg 2018 Dec;120:214-233. Epub 2018 Sep 8 doi: 10.1016/j.wneu.2018.09.001. PMID: 30205225
Central nervous system anomalies in craniofacial microsomia: a systematic review.
Renkema RW, Caron CJJM, Wolvius EB, Dunaway DJ, Forrest CR, Padwa BL, Koudstaal MJ
Int J Oral Maxillofac Surg 2018 Jan;47(1):27-34. Epub 2017 Jul 20 doi: 10.1016/j.ijom.2017.06.009. PMID: 28736116

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