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Hairy palms and soles

MedGen UID:
330667
Concept ID:
C1841694
Congenital Abnormality
Synonyms: Circumscribed hairy dysembryoplasia of palms; Hairy cutaneous malformations of palms and soles; Thickened hair-bearing skin on the palms of both hands
 
Monarch Initiative: MONDO:0007695
OMIM®: 139650

Clinical features

From HPO
Hypermelanotic macule
MedGen UID:
375013
Concept ID:
C1842774
Finding
A hyperpigmented circumscribed area of change in normal skin color without elevation or depression of any size.

Recent clinical studies

Etiology

Carvalho F, Magalhaes C, Fernandez-Llimos F, Mendes J, Gonçalves J
J Therm Biol 2022 Oct;109:103322. Epub 2022 Sep 7 doi: 10.1016/j.jtherbio.2022.103322. PMID: 36195389
Staughton R
Br J Clin Pract Suppl 1990 Sep;71:109-13. PMID: 2091731
Jackson CE, Callies QC, Krull EA, Mehregan A
Arch Dermatol 1975 Sep;111(9):1146-9. PMID: 810092

Diagnosis

Carvalho F, Magalhaes C, Fernandez-Llimos F, Mendes J, Gonçalves J
J Therm Biol 2022 Oct;109:103322. Epub 2022 Sep 7 doi: 10.1016/j.jtherbio.2022.103322. PMID: 36195389
Posthuma JJ, de Ruiter KJ, de Jong VM, Schepers T
J Foot Ankle Surg 2018 Nov-Dec;57(6):1253-1255. Epub 2018 Aug 23 doi: 10.1053/j.jfas.2018.03.042. PMID: 30146338
Haseleu J, Omerbašić D, Frenzel H, Gross M, Lewin GR
PLoS One 2014;9(1):e84949. Epub 2014 Jan 8 doi: 10.1371/journal.pone.0084949. PMID: 24416318Free PMC Article
Basterzi Y, Sari A, Ayhan S
Dermatol Surg 2002 Jul;28(7):639-40. doi: 10.1046/j.1524-4725.2002.01314.x. PMID: 12135526
Akiyama M, Dale BA, Smith LT, Shimizu H, Holbrook KA
Prenat Diagn 1998 May;18(5):425-36. PMID: 9621376

Therapy

Posthuma JJ, de Ruiter KJ, de Jong VM, Schepers T
J Foot Ankle Surg 2018 Nov-Dec;57(6):1253-1255. Epub 2018 Aug 23 doi: 10.1053/j.jfas.2018.03.042. PMID: 30146338

Clinical prediction guides

Akiyama M, Dale BA, Smith LT, Shimizu H, Holbrook KA
Prenat Diagn 1998 May;18(5):425-36. PMID: 9621376
Jackson CE, Callies QC, Krull EA, Mehregan A
Arch Dermatol 1975 Sep;111(9):1146-9. PMID: 810092

Supplemental Content

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