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Grouped pigmentation of the retina

MedGen UID:
341100
•Concept ID:
C1856244
•
Disease or Syndrome
Synonym: GROUPED PIGMENTATION OF RETINAL PIGMENT EPITHELIUM
 
Monarch Initiative: MONDO:0009311
OMIM®: 233800

Definition

Congenital grouped pigmentation of the retina is a rare disorder characterized by a grouping together of round to oval spots of pigment in one or more quadrants of the retina, except for the macula (summary by Renardel de Lavalette et al., 1991). [from OMIM]

Clinical features

From HPO
Metamorphopsia
MedGen UID:
75739
•Concept ID:
C0271185
•
Sign or Symptom
A visual anomaly in which images appear distorted. A grid of straight lines appears wavy and parts of the grid may appear blank.
See: Feature record | Search on this feature
Abnormality of retinal pigmentation
MedGen UID:
350681
•Concept ID:
C1862475
•
Finding
See: Feature record | Search on this feature

Professional guidelines

PubMed

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Ophthalmology 2021 Mar;128(3):443-452. Epub 2020 Aug 11 doi: 10.1016/j.ophtha.2020.08.006. PMID: 32795496

Recent clinical studies

Etiology

Three cases of grouped pigmentation of the retina.
Yoshida T, Adachi-Usami E, Kimura T
Ophthalmologica 1995;209(2):101-5. doi: 10.1159/000310590. PMID: 7746641
Histopathologic findings in congenital grouped pigmentation of the retina.
Regillo CD, Eagle RC Jr, Shields JA, Shields CL, Arbizo VV
Ophthalmology 1993 Mar;100(3):400-5. doi: 10.1016/s0161-6420(93)31635-0. PMID: 8460012
Familial congenital grouped pigmentation of the retina.
Renardel de Lavalette VW, Cruysberg JR, Deutman AF
Am J Ophthalmol 1991 Oct 15;112(4):406-9. doi: 10.1016/s0002-9394(14)76248-8. PMID: 1928243
Congenital grouped pigmentation of the retina. Histopathologic description and report of a case.
Shields JA, Tso MO
Arch Ophthalmol 1975 Nov;93(11):1153. doi: 10.1001/archopht.1975.01010020861007. PMID: 1191104
Grouped pigmentation of the retina.
SUKUMLYN SW
Am J Ophthalmol 1946 Nov;29(11):1458. PMID: 20276986

Diagnosis

Bilateral congenital grouped pigmentation of the retina in one girl and bilateral congenital albinotic spots of the retina in her sister.
Kadoi C, Hayasaka S, Hayasaka Y, Matsumoto M, Nagaki Y
Retina 1999;19(6):571-2. doi: 10.1097/00006982-199919060-00020. PMID: 10606465
Persistent hyperplastic primary vitreous in the right eye and congenital grouped pigmentation of the retina in the left.
Fujii M, Hayasaka S, Setogawa T
Ophthalmologica 1989;198(3):135-9. doi: 10.1159/000309977. PMID: 2498796
Congenital grouped pigmentation of the retina. Histopathologic description and report of a case.
Shields JA, Tso MO
Arch Ophthalmol 1975 Nov;93(11):1153. doi: 10.1001/archopht.1975.01010020861007. PMID: 1191104

Clinical prediction guides

Retinal pigmentation due to choroidal melano-sarcoma with observations on congenital grouped pigmentation of the retina.
LINDSAY A
Br J Ophthalmol 1955 Feb;39(2):114-8. doi: 10.1136/bjo.39.2.114. PMID: 14351675Free PMC Article

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