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Apocrine hidrocystoma

MedGen UID:: 352833
•Concept ID:: C1704335
•: Neoplastic Process

Synonyms:	Apocrine cystadenoma; Apocrine Hidrocystoma; Apocrine Hydrocystoma; Apocrine hydrocystoma
SNOMED CT:	Apocrine cystadenoma (36318001); Apocrine hydrocystoma (254725004); Apocrine cystadenoma (254725004); Apocrine hidrocystoma (254725004)

HPO:	HP:0031454

Definition

A cystic lesions that forms a benign tumor of an apocrine sweat gland. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVApocrine hidrocystoma

Apocrine adenoma
- Apocrine adenoma
  - Apocrine adenoma
    - Apocrine adenoma
      - Apocrine adenoma
        Apocrine adenoma
        Apocrine hidrocystoma

Conditions with this feature

SchC6pf-Schulz-Passarge syndrome

MedGen UID:: 347366
•Concept ID:: C1857069
•: Disease or Syndrome

Schopf-Schulz-Passarge syndrome (SSPS) is an autosomal recessive disorder characterized by a constellation of multiple eyelid cysts, hypodontia, hypotrichosis, palmoplantar hyperkeratosis, and onychodystrophy (summary by Mallaiah and Dickinson, 2001).

See: Condition Record

SchC6pf-Schulz-Passarge syndrome

Professional guidelines

PubMed

Multiple apocrine hidrocystomas: treatment with carbon dioxide laser vaporization.

del Pozo J, García-Silva J, Peña-Penabad C, Fonseca E
J Dermatolog Treat 2001 Jun;12(2):97-100. doi: 10.1080/095466301317085381. PMID: 12243666

See all (1)

Recent clinical studies

Etiology

Apocrine cystadenoma: A long-standing apocrine hidrocystoma with an adenomatous proliferation.

Connolly DM, McGeehin EL, Lee JB
J Cutan Pathol 2024 Mar;51(3):251-257. Epub 2023 Dec 12 doi: 10.1111/cup.14573. PMID: 38084825

A Comparative Study of Immunohistochemical Myoepithelial Cell Markers in Cutaneous Benign Cystic Apocrine Lesions.

Wood A, Houghton SL, Biswas A
Am J Dermatopathol 2016 Jul;38(7):475-83. doi: 10.1097/DAD.0000000000000431. PMID: 26630681

GATA3 Expression in Normal Skin and in Benign and Malignant Epidermal and Cutaneous Adnexal Neoplasms.

Mertens RB, de Peralta-Venturina MN, Balzer BL, Frishberg DP
Am J Dermatopathol 2015 Dec;37(12):885-91. doi: 10.1097/DAD.0000000000000306. PMID: 26595821 Free PMC Article

Apocrine cystadenoma and apocrine hidrocystoma: examination of 21 cases with emphasis on nomenclature according to proliferative features.

Sugiyama A, Sugiura M, Piris A, Tomita Y, Mihm MC
J Cutan Pathol 2007 Dec;34(12):912-7. doi: 10.1111/j.1600-0560.2007.00757.x. PMID: 18001413

Treatment of multiple apocrine hidrocystomas with trichloroacetic acid.

Dailey RA, Saulny SM, Tower RN
Ophthalmic Plast Reconstr Surg 2005 Mar;21(2):148-50. doi: 10.1097/01.iop.0000155509.54813.93. PMID: 15778671

See all (9)

Diagnosis

Apocrine Hidrocystoma of the Parotid Gland.

Kharrat I, Achour I, Thabet W, Chaabouni MA, Trigui M, Triki M, Hammami B, Charfeddine I
Ear Nose Throat J 2023 Nov;102(11):NP549-NP551. Epub 2021 Jul 5 doi: 10.1177/01455613211031028. PMID: 34219505

Postauricular apocrine hidrocystoma: a case and dermoscopy review.

Cavanagh M, Pham M, Nguyen J, Tarbox M
Dermatol Online J 2021 Dec 15;27(12) doi: 10.5070/D3271256705. PMID: 35499435

Epibulbar Subconjunctival Apocrine Hidrocystoma.

Charles NC, Raju LV, Kim ET
Ophthalmic Plast Reconstr Surg 2021 Nov-Dec 01;37(6):e208-e209. doi: 10.1097/IOP.0000000000002019. PMID: 34284427

Intraconal Orbital Hidrocystoma in an Infant.

Bagheri A, Veisi A, Rikhtehgar MH, Kanavi MR
J Craniofac Surg 2021 Jul-Aug 01;32(5):e444-e446. doi: 10.1097/SCS.0000000000007257. PMID: 33235165

Zebras in Foreskin Dermatopathology: A Review.

Alhatem A, Patel N, Lambert WC, Heller DS
J Low Genit Tract Dis 2019 Jul;23(3):235-240. doi: 10.1097/LGT.0000000000000478. PMID: 31149956

See all (54)

Therapy

Recurrent apocrine hidrocystoma of the external auditory canal.

Birkenbeuel J, Goshtasbi K, Mahboubi H, Djalilian HR
Am J Otolaryngol 2019 Mar-Apr;40(2):312-313. Epub 2019 Jan 28 doi: 10.1016/j.amjoto.2019.01.011. PMID: 30717993 Free PMC Article

Multiple apocrine hidrocystoma of the face treated with a 1450-nm diode laser.

Echague AV, Astner S, Chen AA, Anderson RR
Arch Dermatol 2005 Nov;141(11):1365-7. doi: 10.1001/archderm.141.11.1365. PMID: 16301382

Treatment of multiple apocrine hidrocystomas with trichloroacetic acid.

Dailey RA, Saulny SM, Tower RN
Ophthalmic Plast Reconstr Surg 2005 Mar;21(2):148-50. doi: 10.1097/01.iop.0000155509.54813.93. PMID: 15778671

See all (3)

Prognosis

Cutaneous adenomyoepithelioma with histopathological heterogeneity: A case report.

Shiomi T, Matsuno T, Nishimura H, Moriya T
Pathol Int 2021 Nov;71(11):783-788. Epub 2021 Sep 2 doi: 10.1111/pin.13157. PMID: 34473865

Recurrent Giant Apocrine Hidrocystoma of the Leg: A Case Report.

Boddapati V, Aderibigbe T, Gimenez EV, Sarpong NO, Tyler WK
JBJS Case Connect 2020 Jul-Sep;10(3):e19.00608. doi: 10.2106/JBJS.CC.19.00608. PMID: 32668136

A Comparative Study of Immunohistochemical Myoepithelial Cell Markers in Cutaneous Benign Cystic Apocrine Lesions.

Wood A, Houghton SL, Biswas A
Am J Dermatopathol 2016 Jul;38(7):475-83. doi: 10.1097/DAD.0000000000000431. PMID: 26630681

"Apocrine Hidrocystoma and Cystadenoma"-like Tumor of the Digits or Toes: A Potential Diagnostic Pitfall of Digital Papillary Adenocarcinoma.

Molina-Ruiz AM, Llamas-Velasco M, Rütten A, Cerroni L, Requena L
Am J Surg Pathol 2016 Mar;40(3):410-8. doi: 10.1097/PAS.0000000000000547. PMID: 26523544

Expression of S100 protein family members in normal skin and sweat gland tumors.

Zhu L, Okano S, Takahara M, Chiba T, Tu Y, Oda Y, Furue M
J Dermatol Sci 2013 Jun;70(3):211-9. Epub 2013 Mar 16 doi: 10.1016/j.jdermsci.2013.03.002. PMID: 23623205

See all (7)

Clinical prediction guides

Apocrine cystadenoma: A long-standing apocrine hidrocystoma with an adenomatous proliferation.

Connolly DM, McGeehin EL, Lee JB
J Cutan Pathol 2024 Mar;51(3):251-257. Epub 2023 Dec 12 doi: 10.1111/cup.14573. PMID: 38084825

Cutaneous adenomyoepithelioma with histopathological heterogeneity: A case report.

Shiomi T, Matsuno T, Nishimura H, Moriya T
Pathol Int 2021 Nov;71(11):783-788. Epub 2021 Sep 2 doi: 10.1111/pin.13157. PMID: 34473865

"Apocrine Hidrocystoma and Cystadenoma"-like Tumor of the Digits or Toes: A Potential Diagnostic Pitfall of Digital Papillary Adenocarcinoma.

Molina-Ruiz AM, Llamas-Velasco M, Rütten A, Cerroni L, Requena L
Am J Surg Pathol 2016 Mar;40(3):410-8. doi: 10.1097/PAS.0000000000000547. PMID: 26523544

Liesegang rings in an apocrine hidrocystoma: a case report and review of literature.

Gilchrist HM, Wick MR, Patterson JW
J Cutan Pathol 2010 Oct;37(10):1064-6. Epub 2010 May 19 doi: 10.1111/j.1600-0560.2010.01559.x. PMID: 20492082

Pigmented apocrine hidrocystoma--a report of two cases and review of the literature. off.

Veraldi S, Gianotti R, Pabisch S, Gasparini G
Clin Exp Dermatol 1991 Jan;16(1):18-21. doi: 10.1111/j.1365-2230.1991.tb00286.x. PMID: 2025927

See all (8)