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Interstitial Disease

MedGen UID:
361547
•Concept ID:
C1881236
•
Disease or Syndrome

Definition

A disease occurring chiefly in the connective-tissue framework of an organ. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInterstitial Disease

Professional guidelines

PubMed

Diagnosis and Management of Fibrotic Interstitial Lung Diseases.
Collins BF, Luppi F
Clin Chest Med 2021 Jun;42(2):321-335. doi: 10.1016/j.ccm.2021.03.008. PMID: 34024407
Consensus Guidelines for Evaluation and Management of Pulmonary Disease in Sjögren's.
Lee AS, Scofield RH, Hammitt KM, Gupta N, Thomas DE, Moua T, Ussavarungsi K, St Clair EW, Meehan R, Dunleavy K, Makara M, Carsons SE, Carteron NL; Consensus Expert Panel (CEP) Members
Chest 2021 Feb;159(2):683-698. Epub 2020 Oct 16 doi: 10.1016/j.chest.2020.10.011. PMID: 33075377Free PMC Article
Diagnostic criteria of systemic sclerosis.
Hudson M, Fritzler MJ
J Autoimmun 2014 Feb-Mar;48-49:38-41. Epub 2014 Jan 22 doi: 10.1016/j.jaut.2013.11.004. PMID: 24461384

Recent clinical studies

Etiology

Interstitial disease associated with connective tissue disease and vasculitis.
Hernández Muñiz S, Olivera Serrano MJ, Jiménez Heffernan JA, Valenzuela C, Caballero Sánchez-Robles P
Radiologia (Engl Ed) 2022 Dec;64 Suppl 3:250-264. doi: 10.1016/j.rxeng.2022.07.004. PMID: 36737164
Thoracic involvement and imaging patterns in IgG4-related disease.
Muller R, Habert P, Ebbo M, Graveleau J, Groh M, Launay D, Audia S, Pugnet G, Cohen F, Perlat A, Benyamine A, Bienvenu B, Gaigne L, Chanez P, Gaubert JY, Schleinitz N
Eur Respir Rev 2021 Dec 31;30(162) Epub 2021 Oct 5 doi: 10.1183/16000617.0078-2021. PMID: 34615698Free PMC Article
Pulmonary manifestations in systemic lupus erythematosus: pleural involvement, acute pneumonitis, chronic interstitial lung disease and diffuse alveolar hemorrhage.
Aguilera-Pickens G, Abud-Mendoza C
Reumatol Clin (Engl Ed) 2018 Sep-Oct;14(5):294-300. doi: 10.1016/j.reuma.2018.03.012. PMID: 29773465
Intravenous immunoglobulins (IVIG) in systemic sclerosis: a challenging yet promising future.
Cantarini L, Rigante D, Vitale A, Napodano S, Sakkas LI, Bogdanos DP, Shoenfeld Y
Immunol Res 2015 Mar;61(3):326-37. doi: 10.1007/s12026-014-8615-z. PMID: 25550086
Uromodulin-associated kidney disease.
Bleyer AJ, Zivná M, Kmoch S
Nephron Clin Pract 2011;118(1):c31-6. Epub 2010 Nov 11 doi: 10.1159/000320889. PMID: 21071970

Diagnosis

Interstitial disease associated with connective tissue disease and vasculitis.
Hernández Muñiz S, Olivera Serrano MJ, Jiménez Heffernan JA, Valenzuela C, Caballero Sánchez-Robles P
Radiologia (Engl Ed) 2022 Dec;64 Suppl 3:250-264. doi: 10.1016/j.rxeng.2022.07.004. PMID: 36737164
Bronchoalveolar lavage: role in the evaluation of pulmonary interstitial disease.
Hogea SP, Tudorache E, Pescaru C, Marc M, Oancea C
Expert Rev Respir Med 2020 Nov;14(11):1117-1130. Epub 2020 Aug 26 doi: 10.1080/17476348.2020.1806063. PMID: 32847429
Pulmonary manifestations in systemic lupus erythematosus: pleural involvement, acute pneumonitis, chronic interstitial lung disease and diffuse alveolar hemorrhage.
Aguilera-Pickens G, Abud-Mendoza C
Reumatol Clin (Engl Ed) 2018 Sep-Oct;14(5):294-300. doi: 10.1016/j.reuma.2018.03.012. PMID: 29773465
T(1) mapping in cardiac MRI.
Radenkovic D, Weingärtner S, Ricketts L, Moon JC, Captur G
Heart Fail Rev 2017 Jul;22(4):415-430. doi: 10.1007/s10741-017-9627-2. PMID: 28623475Free PMC Article
Uromodulin-associated kidney disease.
Bleyer AJ, Zivná M, Kmoch S
Nephron Clin Pract 2011;118(1):c31-6. Epub 2010 Nov 11 doi: 10.1159/000320889. PMID: 21071970

Therapy

Quantitative Image Analysis at Chronic Lung Allograft Dysfunction Onset Predicts Mortality.
Weigt SS, Kim GJ, Jones HD, Ramsey AL, Amubieya O, Abtin F, Pourzand L, Lee J, Shino MY, DerHovanessian A, Stripp B, Noble PW, Sayah DM, Saggar R, Britton I, Lynch JP 3rd, Belperio JA, Goldin J
Transplantation 2022 Jun 1;106(6):1253-1261. Epub 2022 May 23 doi: 10.1097/TP.0000000000003950. PMID: 34534193Free PMC Article
Chest CT Diagnosis and Clinical Management of Drug-Related Pneumonitis in Patients Receiving Molecular Targeting Agents and Immune Checkpoint Inhibitors: A Position Paper From the Fleischner Society.
Johkoh T, Lee KS, Nishino M, Travis WD, Ryu JH, Lee HY, Ryerson CJ, Franquet T, Bankier AA, Brown KK, Goo JM, Kauczor HU, Lynch DA, Nicholson AG, Richeldi L, Schaefer-Prokop CM, Verschakelen J, Raoof S, Rubin GD, Powell C, Inoue Y, Hatabu H
Chest 2021 Mar;159(3):1107-1125. Epub 2021 Jan 12 doi: 10.1016/j.chest.2020.11.027. PMID: 33450293
T(1) mapping in cardiac MRI.
Radenkovic D, Weingärtner S, Ricketts L, Moon JC, Captur G
Heart Fail Rev 2017 Jul;22(4):415-430. doi: 10.1007/s10741-017-9627-2. PMID: 28623475Free PMC Article
Intravenous immunoglobulins (IVIG) in systemic sclerosis: a challenging yet promising future.
Cantarini L, Rigante D, Vitale A, Napodano S, Sakkas LI, Bogdanos DP, Shoenfeld Y
Immunol Res 2015 Mar;61(3):326-37. doi: 10.1007/s12026-014-8615-z. PMID: 25550086
Diagnostics and therapeutic interventions in myocardial interstitial disease, a previously neglected pathology.
Collier P, Ledwidge M, McDonald K
QJM 2012 Aug;105(8):721-4. Epub 2012 May 29 doi: 10.1093/qjmed/hcs072. PMID: 22647762

Prognosis

Interstitial disease associated with connective tissue disease and vasculitis.
Hernández Muñiz S, Olivera Serrano MJ, Jiménez Heffernan JA, Valenzuela C, Caballero Sánchez-Robles P
Radiologia (Engl Ed) 2022 Dec;64 Suppl 3:250-264. doi: 10.1016/j.rxeng.2022.07.004. PMID: 36737164
Myocardial Amyloidosis: The Exemplar Interstitial Disease.
Fontana M, Ćorović A, Scully P, Moon JC
JACC Cardiovasc Imaging 2019 Nov;12(11 Pt 2):2345-2356. Epub 2019 Aug 14 doi: 10.1016/j.jcmg.2019.06.023. PMID: 31422120
Pulmonary manifestations in systemic lupus erythematosus: pleural involvement, acute pneumonitis, chronic interstitial lung disease and diffuse alveolar hemorrhage.
Aguilera-Pickens G, Abud-Mendoza C
Reumatol Clin (Engl Ed) 2018 Sep-Oct;14(5):294-300. doi: 10.1016/j.reuma.2018.03.012. PMID: 29773465
T(1) mapping in cardiac MRI.
Radenkovic D, Weingärtner S, Ricketts L, Moon JC, Captur G
Heart Fail Rev 2017 Jul;22(4):415-430. doi: 10.1007/s10741-017-9627-2. PMID: 28623475Free PMC Article
Intravenous immunoglobulins (IVIG) in systemic sclerosis: a challenging yet promising future.
Cantarini L, Rigante D, Vitale A, Napodano S, Sakkas LI, Bogdanos DP, Shoenfeld Y
Immunol Res 2015 Mar;61(3):326-37. doi: 10.1007/s12026-014-8615-z. PMID: 25550086

Clinical prediction guides

Thoracic involvement and imaging patterns in IgG4-related disease.
Muller R, Habert P, Ebbo M, Graveleau J, Groh M, Launay D, Audia S, Pugnet G, Cohen F, Perlat A, Benyamine A, Bienvenu B, Gaigne L, Chanez P, Gaubert JY, Schleinitz N
Eur Respir Rev 2021 Dec 31;30(162) Epub 2021 Oct 5 doi: 10.1183/16000617.0078-2021. PMID: 34615698Free PMC Article
Myocardial Amyloidosis: The Exemplar Interstitial Disease.
Fontana M, Ćorović A, Scully P, Moon JC
JACC Cardiovasc Imaging 2019 Nov;12(11 Pt 2):2345-2356. Epub 2019 Aug 14 doi: 10.1016/j.jcmg.2019.06.023. PMID: 31422120
A more tubulocentric view of diabetic kidney disease.
Zeni L, Norden AGW, Cancarini G, Unwin RJ
J Nephrol 2017 Dec;30(6):701-717. Epub 2017 Aug 24 doi: 10.1007/s40620-017-0423-9. PMID: 28840540Free PMC Article
Diagnostics and therapeutic interventions in myocardial interstitial disease, a previously neglected pathology.
Collier P, Ledwidge M, McDonald K
QJM 2012 Aug;105(8):721-4. Epub 2012 May 29 doi: 10.1093/qjmed/hcs072. PMID: 22647762
Pulmonary involvement in rheumatoid arthritis.
Anaya JM, Diethelm L, Ortiz LA, Gutierrez M, Citera G, Welsh RA, Espinoza LR
Semin Arthritis Rheum 1995 Feb;24(4):242-54. doi: 10.1016/s0049-0172(95)80034-4. PMID: 7740304

Recent systematic reviews

Effectivity of mesenchymal stem cells for bleomycin-induced pulmonary fibrosis: a systematic review and implication for clinical application.
Zhao Y, Yan Z, Liu Y, Zhang Y, Shi J, Li J, Ji F
Stem Cell Res Ther 2021 Aug 23;12(1):470. doi: 10.1186/s13287-021-02551-y. PMID: 34420515Free PMC Article
Prognostic role of Krebs von den Lungen-6 (KL-6) measurement in idiopathic pulmonary fibrosis: a systematic review and meta-analysis.
Aloisio E, Braga F, Puricelli C, Panteghini M
Clin Chem Lab Med 2021 Jul 27;59(8):1400-1408. Epub 2021 Apr 9 doi: 10.1515/cclm-2021-0199. PMID: 33831978
The impact of cardiopulmonary manifestations on the mortality of SSc: a systematic review and meta-analysis of observational studies.
Komócsi A, Vorobcsuk A, Faludi R, Pintér T, Lenkey Z, Költo G, Czirják L
Rheumatology (Oxford) 2012 Jun;51(6):1027-36. Epub 2012 Jan 5 doi: 10.1093/rheumatology/ker357. PMID: 22223705

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