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Progressive intervertebral space narrowing

MedGen UID:
373385
•Concept ID:
C1837670
•
Finding
Synonym: Intervertebral space narrowing, progressive
 
HPO: HP:0004622

Definition

A progressive form of decreased height of the intervertebral disk. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProgressive intervertebral space narrowing

Professional guidelines

PubMed

Degenerative lumbar spinal stenosis: evaluation and management.
Issack PS, Cunningham ME, Pumberger M, Hughes AP, Cammisa FP Jr
J Am Acad Orthop Surg 2012 Aug;20(8):527-35. doi: 10.5435/JAAOS-20-08-527. PMID: 22855855

Recent clinical studies

Etiology

Radiological evolution of spinal disease in alkaptonuria and the effect of nitisinone.
Imrich R, Sedláková J, Úlehlová M, Gornall M, Jackson R, Olsson B, Rudebeck M, Gallagher J, Lukáčová O, Mlynáriková V, Stančík R, Vrtíková E, Záňová E, Zaťková A, Arnoux JB, Rovenský J, Luangrath E, Bygott H, Khedr M, Ranganath LR
RMD Open 2022 Oct;8(2) doi: 10.1136/rmdopen-2022-002422. PMID: 36270742Free PMC Article
Number of Levels of Spinal Fusion Associated with the Rate of Joint-Space Narrowing in the Hip.
Kawai T, Shimizu T, Goto K, Kuroda Y, Okuzu Y, Fujibayashi S, Matsuda S
J Bone Joint Surg Am 2021 Jun 2;103(11):953-960. doi: 10.2106/JBJS.20.01578. PMID: 33770019
Twenty-year Longitudinal Follow-up MRI Study of Asymptomatic Volunteers: The Impact of Cervical Alignment on Disk Degeneration.
Okada E, Daimon K, Fujiwara H, Nishiwaki Y, Nojiri K, Watanabe M, Katoh H, Shimizu K, Ishihama H, Fujita N, Tsuji T, Nakamura M, Matsumoto M, Watanabe K
Clin Spine Surg 2018 Dec;31(10):446-451. doi: 10.1097/BSD.0000000000000706. PMID: 30102637
Thoracolumbar Intervertebral Disc Area Morphometry in Elderly Chinese Men and Women: Radiographic Quantifications at Baseline and Changes at Year-4 Follow-up.
Wáng JQ, Káplár Z, Deng M, Griffith JF, Leung JCS, Kwok AWL, Kwok T, Leung PC, Wáng YXJ
Spine (Phila Pa 1976) 2018 May 15;43(10):E607-E614. doi: 10.1097/BRS.0000000000002482. PMID: 29112101
Qualitative and quantitative assessment of degeneration of cervical intervertebral discs and facet joints.
Walraevens J, Liu B, Meersschaert J, Demaerel P, Delye H, Depreitere B, Vander Sloten J, Goffin J
Eur Spine J 2009 Mar;18(3):358-69. Epub 2008 Nov 13 doi: 10.1007/s00586-008-0820-9. PMID: 19005690Free PMC Article

Diagnosis

Radiological evolution of spinal disease in alkaptonuria and the effect of nitisinone.
Imrich R, Sedláková J, Úlehlová M, Gornall M, Jackson R, Olsson B, Rudebeck M, Gallagher J, Lukáčová O, Mlynáriková V, Stančík R, Vrtíková E, Záňová E, Zaťková A, Arnoux JB, Rovenský J, Luangrath E, Bygott H, Khedr M, Ranganath LR
RMD Open 2022 Oct;8(2) doi: 10.1136/rmdopen-2022-002422. PMID: 36270742Free PMC Article
Thoracolumbar Intervertebral Disc Area Morphometry in Elderly Chinese Men and Women: Radiographic Quantifications at Baseline and Changes at Year-4 Follow-up.
Wáng JQ, Káplár Z, Deng M, Griffith JF, Leung JCS, Kwok AWL, Kwok T, Leung PC, Wáng YXJ
Spine (Phila Pa 1976) 2018 May 15;43(10):E607-E614. doi: 10.1097/BRS.0000000000002482. PMID: 29112101
Degenerative lumbar spinal stenosis: evaluation and management.
Issack PS, Cunningham ME, Pumberger M, Hughes AP, Cammisa FP Jr
J Am Acad Orthop Surg 2012 Aug;20(8):527-35. doi: 10.5435/JAAOS-20-08-527. PMID: 22855855
Qualitative and quantitative assessment of degeneration of cervical intervertebral discs and facet joints.
Walraevens J, Liu B, Meersschaert J, Demaerel P, Delye H, Depreitere B, Vander Sloten J, Goffin J
Eur Spine J 2009 Mar;18(3):358-69. Epub 2008 Nov 13 doi: 10.1007/s00586-008-0820-9. PMID: 19005690Free PMC Article
Imaging in dialysis spondyloarthropathy.
Theodorou DJ, Theodorou SJ, Resnick D
Semin Dial 2002 Jul-Aug;15(4):290-6. doi: 10.1046/j.1525-139x.2002.00070.x. PMID: 12191028

Therapy

Radiological evolution of spinal disease in alkaptonuria and the effect of nitisinone.
Imrich R, Sedláková J, Úlehlová M, Gornall M, Jackson R, Olsson B, Rudebeck M, Gallagher J, Lukáčová O, Mlynáriková V, Stančík R, Vrtíková E, Záňová E, Zaťková A, Arnoux JB, Rovenský J, Luangrath E, Bygott H, Khedr M, Ranganath LR
RMD Open 2022 Oct;8(2) doi: 10.1136/rmdopen-2022-002422. PMID: 36270742Free PMC Article
Thoracolumbar Intervertebral Disc Area Morphometry in Elderly Chinese Men and Women: Radiographic Quantifications at Baseline and Changes at Year-4 Follow-up.
Wáng JQ, Káplár Z, Deng M, Griffith JF, Leung JCS, Kwok AWL, Kwok T, Leung PC, Wáng YXJ
Spine (Phila Pa 1976) 2018 May 15;43(10):E607-E614. doi: 10.1097/BRS.0000000000002482. PMID: 29112101
Degenerative lumbar spinal stenosis: evaluation and management.
Issack PS, Cunningham ME, Pumberger M, Hughes AP, Cammisa FP Jr
J Am Acad Orthop Surg 2012 Aug;20(8):527-35. doi: 10.5435/JAAOS-20-08-527. PMID: 22855855
Failed back surgery syndrome: the role of symptomatic segmental single-level instability after lumbar microdiscectomy.
Schaller B
Eur Spine J 2004 May;13(3):193-8. Epub 2004 Jan 30 doi: 10.1007/s00586-003-0632-x. PMID: 14752624Free PMC Article
Imaging in dialysis spondyloarthropathy.
Theodorou DJ, Theodorou SJ, Resnick D
Semin Dial 2002 Jul-Aug;15(4):290-6. doi: 10.1046/j.1525-139x.2002.00070.x. PMID: 12191028

Prognosis

Ten-year Longitudinal Follow-up MRI Study of Age-related Changes in Thoracic Intervertebral Discs in Asymptomatic Subjects.
Okada E, Daimon K, Fujiwara H, Nishiwaki Y, Nojiri K, Watanabe M, Katoh H, Ishihama H, Fujita N, Tsuji T, Nakamura M, Matsumoto M, Watanabe K
Spine (Phila Pa 1976) 2019 Nov 15;44(22):E1317-E1324. doi: 10.1097/BRS.0000000000003145. PMID: 31348175
Twenty-year Longitudinal Follow-up MRI Study of Asymptomatic Volunteers: The Impact of Cervical Alignment on Disk Degeneration.
Okada E, Daimon K, Fujiwara H, Nishiwaki Y, Nojiri K, Watanabe M, Katoh H, Shimizu K, Ishihama H, Fujita N, Tsuji T, Nakamura M, Matsumoto M, Watanabe K
Clin Spine Surg 2018 Dec;31(10):446-451. doi: 10.1097/BSD.0000000000000706. PMID: 30102637
Thoracolumbar Intervertebral Disc Area Morphometry in Elderly Chinese Men and Women: Radiographic Quantifications at Baseline and Changes at Year-4 Follow-up.
Wáng JQ, Káplár Z, Deng M, Griffith JF, Leung JCS, Kwok AWL, Kwok T, Leung PC, Wáng YXJ
Spine (Phila Pa 1976) 2018 May 15;43(10):E607-E614. doi: 10.1097/BRS.0000000000002482. PMID: 29112101
Longitudinal magnetic resonance imaging study on whiplash injury patients: minimum 10-year follow-up.
Ichihara D, Okada E, Chiba K, Toyama Y, Fujiwara H, Momoshima S, Nishiwaki Y, Hashimoto T, Ogawa J, Watanabe M, Takahata T, Matsumoto M
J Orthop Sci 2009 Sep;14(5):602-10. Epub 2009 Oct 3 doi: 10.1007/s00776-009-1378-z. PMID: 19802673
Qualitative and quantitative assessment of degeneration of cervical intervertebral discs and facet joints.
Walraevens J, Liu B, Meersschaert J, Demaerel P, Delye H, Depreitere B, Vander Sloten J, Goffin J
Eur Spine J 2009 Mar;18(3):358-69. Epub 2008 Nov 13 doi: 10.1007/s00586-008-0820-9. PMID: 19005690Free PMC Article

Clinical prediction guides

Twenty-year Longitudinal Follow-up MRI Study of Asymptomatic Volunteers: The Impact of Cervical Alignment on Disk Degeneration.
Okada E, Daimon K, Fujiwara H, Nishiwaki Y, Nojiri K, Watanabe M, Katoh H, Shimizu K, Ishihama H, Fujita N, Tsuji T, Nakamura M, Matsumoto M, Watanabe K
Clin Spine Surg 2018 Dec;31(10):446-451. doi: 10.1097/BSD.0000000000000706. PMID: 30102637
Thoracic range of motion, stability, and correlation to imaging-determined degeneration.
Healy AT, Mageswaran P, Lubelski D, Rosenbaum BP, Matheus V, Benzel EC, Mroz TE
J Neurosurg Spine 2015 Aug;23(2):170-7. Epub 2015 May 15 doi: 10.3171/2014.12.SPINE131112. PMID: 25978074
Prevalence and sex difference of lumbar disc space narrowing in elderly chinese men and women: osteoporotic fractures in men (Hong Kong) and osteoporotic fractures in women (Hong Kong) studies.
Wang YX, Griffith JF, Zeng XJ, Deng M, Kwok AW, Leung JC, Ahuja AT, Kwok T, Leung PC
Arthritis Rheum 2013 Apr;65(4):1004-10. doi: 10.1002/art.37857. PMID: 23335175Free PMC Article
Qualitative and quantitative assessment of degeneration of cervical intervertebral discs and facet joints.
Walraevens J, Liu B, Meersschaert J, Demaerel P, Delye H, Depreitere B, Vander Sloten J, Goffin J
Eur Spine J 2009 Mar;18(3):358-69. Epub 2008 Nov 13 doi: 10.1007/s00586-008-0820-9. PMID: 19005690Free PMC Article
Progression of lumbosacral isthmic spondylolisthesis in adults.
Floman Y
Spine (Phila Pa 1976) 2000 Feb 1;25(3):342-7. doi: 10.1097/00007632-200002010-00014. PMID: 10703107

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