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Seasonal affective disorder(SAD)

MedGen UID:
38984
Concept ID:
C0085159
Mental or Behavioral Dysfunction
Synonym: SAD
SNOMED CT: Seasonal affective disorder (247803002); SAD - Seasonal affective disorder (247803002)
 
Monarch Initiative: MONDO:0000694
OMIM®: 608516

Definition

A syndrome characterized by depressions that recur annually at the same time each year, usually during the winter months. Other symptoms include anxiety, irritability, decreased energy, increased appetite (carbohydrate cravings), increased duration of sleep, and weight gain. sad (seasonal affective disorder) can be treated by daily exposure to bright artificial lights (phototherapy), during the season of recurrence. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSeasonal affective disorder

Professional guidelines

PubMed

Chen ZW, Zhang XF, Tu ZM
J Affect Disord 2024 Apr 1;350:531-536. Epub 2024 Jan 12 doi: 10.1016/j.jad.2024.01.028. PMID: 38220102
Pjrek E, Friedrich ME, Cambioli L, Dold M, Jäger F, Komorowski A, Lanzenberger R, Kasper S, Winkler D
Psychother Psychosom 2020;89(1):17-24. Epub 2019 Oct 1 doi: 10.1159/000502891. PMID: 31574513
Niemegeers P, Dumont GJ, Patteet L, Neels H, Sabbe BG
Expert Opin Drug Metab Toxicol 2013 Sep;9(9):1229-40. Epub 2013 May 27 doi: 10.1517/17425255.2013.804062. PMID: 23705752

Recent clinical studies

Etiology

Galima SV, Vogel SR, Kowalski AW
Am Fam Physician 2020 Dec 1;102(11):668-672. PMID: 33252911
Pjrek E, Friedrich ME, Cambioli L, Dold M, Jäger F, Komorowski A, Lanzenberger R, Kasper S, Winkler D
Psychother Psychosom 2020;89(1):17-24. Epub 2019 Oct 1 doi: 10.1159/000502891. PMID: 31574513
Kurlansik SL, Ibay AD
Am Fam Physician 2012 Dec 1;86(11):1037-41. PMID: 23198671
Wilkes S
Drugs Today (Barc) 2006 Oct;42(10):671-81. doi: 10.1358/dot.2006.42.10.1025701. PMID: 17136226
Lurie SJ, Gawinski B, Pierce D, Rousseau SJ
Am Fam Physician 2006 Nov 1;74(9):1521-4. PMID: 17111890

Diagnosis

Galima SV, Vogel SR, Kowalski AW
Am Fam Physician 2020 Dec 1;102(11):668-672. PMID: 33252911
Tao L, Jiang R, Zhang K, Qian Z, Chen P, Lv Y, Yao Y
Psychiatry Res 2020 Sep;291:113247. Epub 2020 Jun 22 doi: 10.1016/j.psychres.2020.113247. PMID: 32622169
Wescott DL, Soehner AM, Roecklein KA
Curr Opin Psychol 2020 Aug;34:7-11. Epub 2019 Aug 26 doi: 10.1016/j.copsyc.2019.08.023. PMID: 31536962Free PMC Article
Kurlansik SL, Ibay AD
Am Fam Physician 2012 Dec 1;86(11):1037-41. PMID: 23198671
Danilenko KV, Levitan RD
Handb Clin Neurol 2012;106:279-89. doi: 10.1016/B978-0-444-52002-9.00017-6. PMID: 22608628

Therapy

Do A, Li VW, Huang S, Michalak EE, Tam EM, Chakrabarty T, Yatham LN, Lam RW
Can J Psychiatry 2022 Oct;67(10):745-754. Epub 2022 May 6 doi: 10.1177/07067437221097903. PMID: 35522196Free PMC Article
Galima SV, Vogel SR, Kowalski AW
Am Fam Physician 2020 Dec 1;102(11):668-672. PMID: 33252911
Tao L, Jiang R, Zhang K, Qian Z, Chen P, Lv Y, Yao Y
Psychiatry Res 2020 Sep;291:113247. Epub 2020 Jun 22 doi: 10.1016/j.psychres.2020.113247. PMID: 32622169
Pjrek E, Friedrich ME, Cambioli L, Dold M, Jäger F, Komorowski A, Lanzenberger R, Kasper S, Winkler D
Psychother Psychosom 2020;89(1):17-24. Epub 2019 Oct 1 doi: 10.1159/000502891. PMID: 31574513
Kurlansik SL, Ibay AD
Am Fam Physician 2012 Dec 1;86(11):1037-41. PMID: 23198671

Prognosis

Fonte A, Coutinho B
BMC Psychiatry 2021 Jun 29;21(1):317. doi: 10.1186/s12888-021-03313-z. PMID: 34187417Free PMC Article
Leahy LG
J Psychosoc Nurs Ment Health Serv 2017 Nov 1;55(11):10-14. doi: 10.3928/02793695-20171016-03. PMID: 29084340
Borbély AA, Daan S, Wirz-Justice A, Deboer T
J Sleep Res 2016 Apr;25(2):131-43. Epub 2016 Jan 14 doi: 10.1111/jsr.12371. PMID: 26762182
Osborn J, Raetz J, Kost A
Med Clin North Am 2014 Sep;98(5):1065-77. Epub 2014 Jul 9 doi: 10.1016/j.mcna.2014.06.006. PMID: 25134873
Kurlansik SL, Ibay AD
Am Fam Physician 2012 Dec 1;86(11):1037-41. PMID: 23198671

Clinical prediction guides

Do A, Li VW, Huang S, Michalak EE, Tam EM, Chakrabarty T, Yatham LN, Lam RW
Can J Psychiatry 2022 Oct;67(10):745-754. Epub 2022 May 6 doi: 10.1177/07067437221097903. PMID: 35522196Free PMC Article
Bertrand L, d'Ortho MP, Reynaud E, Lejoyeux M, Bourgin P, Geoffroy PA
J Affect Disord 2021 Sep 1;292:405-415. Epub 2021 Jun 5 doi: 10.1016/j.jad.2021.05.080. PMID: 34144365
Tao L, Jiang R, Zhang K, Qian Z, Chen P, Lv Y, Yao Y
Psychiatry Res 2020 Sep;291:113247. Epub 2020 Jun 22 doi: 10.1016/j.psychres.2020.113247. PMID: 32622169
Pjrek E, Friedrich ME, Cambioli L, Dold M, Jäger F, Komorowski A, Lanzenberger R, Kasper S, Winkler D
Psychother Psychosom 2020;89(1):17-24. Epub 2019 Oct 1 doi: 10.1159/000502891. PMID: 31574513
Green B
Curr Med Res Opin 2011 Apr;27(4):745-9. Epub 2011 Jan 27 doi: 10.1185/03007995.2011.554534. PMID: 21271795

Recent systematic reviews

Do A, Li VW, Huang S, Michalak EE, Tam EM, Chakrabarty T, Yatham LN, Lam RW
Can J Psychiatry 2022 Oct;67(10):745-754. Epub 2022 May 6 doi: 10.1177/07067437221097903. PMID: 35522196Free PMC Article
Bertrand L, d'Ortho MP, Reynaud E, Lejoyeux M, Bourgin P, Geoffroy PA
J Affect Disord 2021 Sep 1;292:405-415. Epub 2021 Jun 5 doi: 10.1016/j.jad.2021.05.080. PMID: 34144365
Cools O, Hebbrecht K, Coppens V, Roosens L, De Witte A, Morrens M, Neels H, Sabbe B
Expert Opin Pharmacother 2018 Aug;19(11):1221-1233. Epub 2018 Jul 26 doi: 10.1080/14656566.2018.1501359. PMID: 30048159
Brouwer A, Nguyen HT, Snoek FJ, van Raalte DH, Beekman ATF, Moll AC, Bremmer MA
Acta Psychiatr Scand 2017 Dec;136(6):534-548. Epub 2017 Sep 10 doi: 10.1111/acps.12785. PMID: 28891192
Kaminski-Hartenthaler A, Nussbaumer B, Forneris CA, Morgan LC, Gaynes BN, Sonis JH, Greenblatt A, Wipplinger J, Lux LJ, Winkler D, Van Noord MG, Hofmann J, Gartlehner G
Cochrane Database Syst Rev 2015 Nov 11;(11):CD011271. doi: 10.1002/14651858.CD011271.pub2. PMID: 26560173

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