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Lassitude

MedGen UID:
39240
•Concept ID:
C0086525
•
Sign or Symptom

Definition

Physical or mental fatigue. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLassitude

Professional guidelines

PubMed

Age as a moderating factor of treatment resistance in depression.
Kautzky A, Bartova L, Fugger G, Dold M, Souery D, Montgomery S, Zohar J, Mendlewicz J, Fabbri C, Serretti A, Rujescu D, Kasper S
Eur Psychiatry 2023 Apr 20;66(1):e35. doi: 10.1192/j.eurpsy.2023.17. PMID: 37078509Free PMC Article
How to optimize HCV therapy in genotype 1 patients: management of side-effects.
Chopra A, Klein PL, Drinnan T, Lee SS
Liver Int 2013 Feb;33 Suppl 1:30-4. doi: 10.1111/liv.12080. PMID: 23286843
High-altitude-related disorders--Part I: Pathophysiology, differential diagnosis, and treatment.
Rodway GW, Hoffman LA, Sanders MH
Heart Lung 2003 Nov-Dec;32(6):353-9. doi: 10.1016/j.hrtlng.2003.08.002. PMID: 14652526

Recent clinical studies

Etiology

Iron Deficiency Anemia: An Updated Review.
Leung AKC, Lam JM, Wong AHC, Hon KL, Li X
Curr Pediatr Rev 2024;20(3):339-356. doi: 10.2174/1573396320666230727102042. PMID: 37497686
White matter microstructure relates to lassitude but not diagnosis in adolescents with depression.
Cullen KR, Brown R, Schreiner MW, Eberly LE, Klimes-Dougan B, Reigstad K, Hill D, Lim KO, Mueller BA
Brain Imaging Behav 2020 Oct;14(5):1507-1520. doi: 10.1007/s11682-019-00078-8. PMID: 30887416Free PMC Article
Acute high-altitude sickness.
Luks AM, Swenson ER, Bärtsch P
Eur Respir Rev 2017 Jan;26(143) Epub 2017 Jan 31 doi: 10.1183/16000617.0096-2016. PMID: 28143879Free PMC Article
How to optimize HCV therapy in genotype 1 patients: management of side-effects.
Chopra A, Klein PL, Drinnan T, Lee SS
Liver Int 2013 Feb;33 Suppl 1:30-4. doi: 10.1111/liv.12080. PMID: 23286843
Environmental toxicology and health effects associated with dinitrotoluene exposure.
Tchounwou PB, Newsome C, Glass K, Centeno JA, Leszczynski J, Bryant J, Okoh J, Ishaque A, Brower M
Rev Environ Health 2003 Jul-Sep;18(3):203-29. doi: 10.1515/reveh.2003.18.3.203. PMID: 14672515

Diagnosis

Iron Deficiency Anemia: An Updated Review.
Leung AKC, Lam JM, Wong AHC, Hon KL, Li X
Curr Pediatr Rev 2024;20(3):339-356. doi: 10.2174/1573396320666230727102042. PMID: 37497686
White matter microstructure relates to lassitude but not diagnosis in adolescents with depression.
Cullen KR, Brown R, Schreiner MW, Eberly LE, Klimes-Dougan B, Reigstad K, Hill D, Lim KO, Mueller BA
Brain Imaging Behav 2020 Oct;14(5):1507-1520. doi: 10.1007/s11682-019-00078-8. PMID: 30887416Free PMC Article
Acute high-altitude sickness.
Luks AM, Swenson ER, Bärtsch P
Eur Respir Rev 2017 Jan;26(143) Epub 2017 Jan 31 doi: 10.1183/16000617.0096-2016. PMID: 28143879Free PMC Article
Liver flukes: the malady neglected.
Lim JH
Korean J Radiol 2011 May-Jun;12(3):269-79. Epub 2011 Apr 25 doi: 10.3348/kjr.2011.12.3.269. PMID: 21603286Free PMC Article
Hyperparathyroidism.
ROONEY JC
Calif Med 1949 Sep;71(3):211-3. PMID: 18137218Free PMC Article

Therapy

Iron Deficiency Anemia: An Updated Review.
Leung AKC, Lam JM, Wong AHC, Hon KL, Li X
Curr Pediatr Rev 2024;20(3):339-356. doi: 10.2174/1573396320666230727102042. PMID: 37497686
Safety of carbonic anhydrase inhibitors.
Swenson ER
Expert Opin Drug Saf 2014 Apr;13(4):459-72. Epub 2014 Mar 10 doi: 10.1517/14740338.2014.897328. PMID: 24611470
How to optimize HCV therapy in genotype 1 patients: management of side-effects.
Chopra A, Klein PL, Drinnan T, Lee SS
Liver Int 2013 Feb;33 Suppl 1:30-4. doi: 10.1111/liv.12080. PMID: 23286843
Citalopram reduces endotoxin-induced fatigue.
Hannestad J, DellaGioia N, Ortiz N, Pittman B, Bhagwagar Z
Brain Behav Immun 2011 Feb;25(2):256-9. Epub 2010 Oct 16 doi: 10.1016/j.bbi.2010.10.013. PMID: 20955776Free PMC Article
Metoclopramide: pharmacology and clinical application.
Albibi R, McCallum RW
Ann Intern Med 1983 Jan;98(1):86-95. doi: 10.7326/0003-4819-98-1-86. PMID: 6336644

Prognosis

Age as a moderating factor of treatment resistance in depression.
Kautzky A, Bartova L, Fugger G, Dold M, Souery D, Montgomery S, Zohar J, Mendlewicz J, Fabbri C, Serretti A, Rujescu D, Kasper S
Eur Psychiatry 2023 Apr 20;66(1):e35. doi: 10.1192/j.eurpsy.2023.17. PMID: 37078509Free PMC Article
Which residual symptoms predict relapse after successful electroconvulsive therapy for late-life depression?
Lambrichts S, Vansteelandt K, Hebbrecht K, Wagenmakers MJ, Oudega ML, Obbels J, van Exel E, Dols A, Bouckaert F, Schrijvers D, Verwijk E, Sienaert P
J Psychiatr Res 2022 Oct;154:111-116. Epub 2022 Jul 31 doi: 10.1016/j.jpsychires.2022.07.056. PMID: 35933854
Depressive symptoms due to stroke are strongly predicted by the volume and location of the cerebral infarction, white matter hyperintensities, hypertension, and age: A precision nomothetic psychiatry analysis.
Jaroonpipatkul C, Onwanna J, Tunvirachaisakul C, Jittapiromsak N, Rakvongthai Y, Chutinet A, Supasitthumrong T, Maes M
J Affect Disord 2022 Jul 15;309:141-150. Epub 2022 Apr 14 doi: 10.1016/j.jad.2022.04.041. PMID: 35430315
Acute high-altitude sickness.
Luks AM, Swenson ER, Bärtsch P
Eur Respir Rev 2017 Jan;26(143) Epub 2017 Jan 31 doi: 10.1183/16000617.0096-2016. PMID: 28143879Free PMC Article
Liver flukes: the malady neglected.
Lim JH
Korean J Radiol 2011 May-Jun;12(3):269-79. Epub 2011 Apr 25 doi: 10.3348/kjr.2011.12.3.269. PMID: 21603286Free PMC Article

Clinical prediction guides

Iron Deficiency Anemia: An Updated Review.
Leung AKC, Lam JM, Wong AHC, Hon KL, Li X
Curr Pediatr Rev 2024;20(3):339-356. doi: 10.2174/1573396320666230727102042. PMID: 37497686
Age as a moderating factor of treatment resistance in depression.
Kautzky A, Bartova L, Fugger G, Dold M, Souery D, Montgomery S, Zohar J, Mendlewicz J, Fabbri C, Serretti A, Rujescu D, Kasper S
Eur Psychiatry 2023 Apr 20;66(1):e35. doi: 10.1192/j.eurpsy.2023.17. PMID: 37078509Free PMC Article
Dimensions of Poststroke Depression and Neuropsychological Deficits in Older Adults.
Kanellopoulos D, Wilkins V, Avari J, Oberlin L, Arader L, Chaplin M, Banerjee S, Alexopoulos GS
Am J Geriatr Psychiatry 2020 Jul;28(7):764-771. Epub 2020 Jan 25 doi: 10.1016/j.jagp.2020.01.009. PMID: 32081532Free PMC Article
Effect of desvenlafaxine 50 mg and 100 mg on energy and lassitude in patients with major depressive disorder: A pooled analysis.
Lam RW, Wajsbrot DB, Meier E, Pappadopulos E, Mackell JA, Boucher M
J Psychopharmacol 2017 Sep;31(9):1204-1214. Epub 2017 Jul 18 doi: 10.1177/0269881117719261. PMID: 28718346
Citalopram reduces endotoxin-induced fatigue.
Hannestad J, DellaGioia N, Ortiz N, Pittman B, Bhagwagar Z
Brain Behav Immun 2011 Feb;25(2):256-9. Epub 2010 Oct 16 doi: 10.1016/j.bbi.2010.10.013. PMID: 20955776Free PMC Article

Recent systematic reviews

Chinese Medicine Syndromes and Stages of Early Breast Cancer: Hierarchical Cluster Analysis and Implication for Clinical Practice.
Guo Q, Chen Q, Xue CC, Zhang AL, Coyle ME
J Altern Complement Med 2021 Nov;27(11):904-914. Epub 2021 Jun 1 doi: 10.1089/acm.2021.0055. PMID: 34076505
Xiaoqinglong decoction (a traditional Chinese medicine) combined conventional treatment for acute exacerbation of chronic obstructive pulmonary disease: A systematic review and meta-analysis.
Gao Z, Jing J, Liu Y
Medicine (Baltimore) 2020 Apr;99(14):e19571. doi: 10.1097/MD.0000000000019571. PMID: 32243375Free PMC Article

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