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Killip Class III

MedGen UID:
394988
•Concept ID:
C2697846
•
Finding

Definition

A classification of myocardial infarction characterized by rales over more than 50% of the lung fields. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVKillip Class III

Professional guidelines

PubMed

In-hospital major adverse cardiovascular events after primary percutaneous coronary intervention in patients with acute ST-segment elevation myocardial infarction: a retrospective study under the China chest pain center (standard center) treatment system.
Huang L, Zhang J, Huang Q, Cui R, Chen J
BMC Cardiovasc Disord 2023 Apr 17;23(1):198. doi: 10.1186/s12872-023-03214-x. PMID: 37069503Free PMC Article
In-hospital outcomes in nonagenarian patients undergoing primary percutaneous coronary intervention.
Angelini F, Franchin L, Bocchino PP, Morici N, Wańha W, Savonitto S, Trabattoni D, Cerrato E, Barbieri L, Fortuni F, DE Luca L, Greco A, DE Filippo O, Montefusco A, Montabone A, Rubino AE, Gili S, Quadri G, Somaschini A, Cornara S, Carugo S, Capodanno D, Wojakowski W, Dusi V, D'Ascenzo F, DE Ferrari GM
Minerva Cardiol Angiol 2023 Oct;71(5):590-598. Epub 2022 Dec 7 doi: 10.23736/S2724-5683.22.06167-1. PMID: 36475546
Outcomes of patients with Killip class III acute myocardial infarction after primary percutaneous coronary intervention.
Tsai TH, Chua S, Hussein H, Leu S, Wu CJ, Hang CL, Fang HY, Chung SY, Fu M, Chen HC, Chang LT, Yeh KH, Yip HK
Crit Care Med 2011 Mar;39(3):436-42. doi: 10.1097/CCM.0b013e318206ccc3. PMID: 21242801

Recent clinical studies

Etiology

Early Statin Therapy and In-Hospital Outcomes in Acute Coronary Syndrome Patients Presenting with Advanced Killip Class at Admission: Findings from the CCC-ACS Project.
Song X, Zhou X, Li Z, Sun H, Liu H, A G, Hao Y, Liu J, Liu J, Zhao D, Yang Q, Li Y; CCC-ACS Investigators
Am J Cardiovasc Drugs 2022 Nov;22(6):685-694. Epub 2022 Aug 13 doi: 10.1007/s40256-022-00546-5. PMID: 35962306
Clinical predictors and prognostic role of high Killip class in patients with a first episode of anterior ST-segment elevation acute myocardial infarction.
Del Buono MG, Montone RA, Rinaldi R, Gurgoglione FL, Meucci MC, Camilli M, Iannaccone G, Sanna T, Pedicino D, Trani C, Niccoli G, Crea F
J Cardiovasc Med (Hagerstown) 2021 Jul 1;22(7):530-538. doi: 10.2459/JCM.0000000000001168. PMID: 34076600
Prospective ARNI vs. ACE inhibitor trial to DetermIne Superiority in reducing heart failure Events after Myocardial Infarction (PARADISE-MI): design and baseline characteristics.
Jering KS, Claggett B, Pfeffer MA, Granger C, Køber L, Lewis EF, Maggioni AP, Mann D, McMurray JJV, Rouleau JL, Solomon SD, Steg PG, van der Meer P, Wernsing M, Carter K, Guo W, Zhou Y, Lefkowitz M, Gong J, Wang Y, Merkely B, Macin SM, Shah U, Nicolau JC, Braunwald E
Eur J Heart Fail 2021 Jun;23(6):1040-1048. Epub 2021 Apr 22 doi: 10.1002/ejhf.2191. PMID: 33847047
The effect of complete revascularization in patients with ST-segment elevation myocardial infarction with Killip class ≥ III.
Lee WC, Chen TY, Chen CJ, Yang CH, Fang CY, Wu CJ, Fang HY
Coron Artery Dis 2020 Jan;31(1):13-19. doi: 10.1097/MCA.0000000000000815. PMID: 31658147Free PMC Article
Outcomes of patients with Killip class III acute myocardial infarction after primary percutaneous coronary intervention.
Tsai TH, Chua S, Hussein H, Leu S, Wu CJ, Hang CL, Fang HY, Chung SY, Fu M, Chen HC, Chang LT, Yeh KH, Yip HK
Crit Care Med 2011 Mar;39(3):436-42. doi: 10.1097/CCM.0b013e318206ccc3. PMID: 21242801

Diagnosis

Clinical features of ST-segment elevation myocardial infarction in young Chinese patients.
Sun Y, Xu J, He Z, Cheng X, Jiang T
Cardiol J 2023;30(4):627-635. Epub 2021 Jul 27 doi: 10.5603/CJ.a2021.0059. PMID: 34312831Free PMC Article
Early Statin Therapy and In-Hospital Outcomes in Acute Coronary Syndrome Patients Presenting with Advanced Killip Class at Admission: Findings from the CCC-ACS Project.
Song X, Zhou X, Li Z, Sun H, Liu H, A G, Hao Y, Liu J, Liu J, Zhao D, Yang Q, Li Y; CCC-ACS Investigators
Am J Cardiovasc Drugs 2022 Nov;22(6):685-694. Epub 2022 Aug 13 doi: 10.1007/s40256-022-00546-5. PMID: 35962306
Clinical predictors and prognostic role of high Killip class in patients with a first episode of anterior ST-segment elevation acute myocardial infarction.
Del Buono MG, Montone RA, Rinaldi R, Gurgoglione FL, Meucci MC, Camilli M, Iannaccone G, Sanna T, Pedicino D, Trani C, Niccoli G, Crea F
J Cardiovasc Med (Hagerstown) 2021 Jul 1;22(7):530-538. doi: 10.2459/JCM.0000000000001168. PMID: 34076600
The effect of complete revascularization in patients with ST-segment elevation myocardial infarction with Killip class ≥ III.
Lee WC, Chen TY, Chen CJ, Yang CH, Fang CY, Wu CJ, Fang HY
Coron Artery Dis 2020 Jan;31(1):13-19. doi: 10.1097/MCA.0000000000000815. PMID: 31658147Free PMC Article
Long-term prognosis and risk heterogeneity of heart failure complicating acute myocardial infarction.
de Carvalho LP, Gao F, Chen Q, Sim LL, Koh TH, Foo D, Ong HY, Tong KL, Tan HC, Yeo TC, Chow KY, Richards AM, Peterson ED, Chua T, Chan MY
Am J Cardiol 2015 Apr 1;115(7):872-8. Epub 2015 Jan 15 doi: 10.1016/j.amjcard.2015.01.010. PMID: 25682439

Therapy

In-hospital major adverse cardiovascular events after primary percutaneous coronary intervention in patients with acute ST-segment elevation myocardial infarction: a retrospective study under the China chest pain center (standard center) treatment system.
Huang L, Zhang J, Huang Q, Cui R, Chen J
BMC Cardiovasc Disord 2023 Apr 17;23(1):198. doi: 10.1186/s12872-023-03214-x. PMID: 37069503Free PMC Article
Early Statin Therapy and In-Hospital Outcomes in Acute Coronary Syndrome Patients Presenting with Advanced Killip Class at Admission: Findings from the CCC-ACS Project.
Song X, Zhou X, Li Z, Sun H, Liu H, A G, Hao Y, Liu J, Liu J, Zhao D, Yang Q, Li Y; CCC-ACS Investigators
Am J Cardiovasc Drugs 2022 Nov;22(6):685-694. Epub 2022 Aug 13 doi: 10.1007/s40256-022-00546-5. PMID: 35962306
Clinical predictors and prognostic role of high Killip class in patients with a first episode of anterior ST-segment elevation acute myocardial infarction.
Del Buono MG, Montone RA, Rinaldi R, Gurgoglione FL, Meucci MC, Camilli M, Iannaccone G, Sanna T, Pedicino D, Trani C, Niccoli G, Crea F
J Cardiovasc Med (Hagerstown) 2021 Jul 1;22(7):530-538. doi: 10.2459/JCM.0000000000001168. PMID: 34076600
Prospective ARNI vs. ACE inhibitor trial to DetermIne Superiority in reducing heart failure Events after Myocardial Infarction (PARADISE-MI): design and baseline characteristics.
Jering KS, Claggett B, Pfeffer MA, Granger C, Køber L, Lewis EF, Maggioni AP, Mann D, McMurray JJV, Rouleau JL, Solomon SD, Steg PG, van der Meer P, Wernsing M, Carter K, Guo W, Zhou Y, Lefkowitz M, Gong J, Wang Y, Merkely B, Macin SM, Shah U, Nicolau JC, Braunwald E
Eur J Heart Fail 2021 Jun;23(6):1040-1048. Epub 2021 Apr 22 doi: 10.1002/ejhf.2191. PMID: 33847047
Do beta-blockers reduce short-term mortality following acute myocardial infarction? A systematic review and meta-analysis.
Al-Reesi A, Al-Zadjali N, Perry J, Fergusson D, Al-Shamsi M, Al-Thagafi M, Stiell I
CJEM 2008 May;10(3):215-23. doi: 10.1017/s1481803500010137. PMID: 19019272

Prognosis

Clinical predictors and prognostic role of high Killip class in patients with a first episode of anterior ST-segment elevation acute myocardial infarction.
Del Buono MG, Montone RA, Rinaldi R, Gurgoglione FL, Meucci MC, Camilli M, Iannaccone G, Sanna T, Pedicino D, Trani C, Niccoli G, Crea F
J Cardiovasc Med (Hagerstown) 2021 Jul 1;22(7):530-538. doi: 10.2459/JCM.0000000000001168. PMID: 34076600
Outcomes of Nonagenarians With ST Elevation Myocardial Infarction.
Cepas-Guillén PL, Borrego-Rodriguez J, Flores-Umanzor E, Echarte-Morales J, Fernandez-Valledor A, Menendez-Suarez P, Vazquez S, Alonso N, Ortiz JT, Regueiro A, Iglesias I, Andrea R, Masotti M, Perez de Prado A, Brugaletta S, Bayón-Fernandez J, Freixa X, Fernandez-Vazquez F, Sabaté M
Am J Cardiol 2020 Jan 1;125(1):11-18. Epub 2019 Oct 11 doi: 10.1016/j.amjcard.2019.09.046. PMID: 31732135
The effect of complete revascularization in patients with ST-segment elevation myocardial infarction with Killip class ≥ III.
Lee WC, Chen TY, Chen CJ, Yang CH, Fang CY, Wu CJ, Fang HY
Coron Artery Dis 2020 Jan;31(1):13-19. doi: 10.1097/MCA.0000000000000815. PMID: 31658147Free PMC Article
Long-term prognosis and risk heterogeneity of heart failure complicating acute myocardial infarction.
de Carvalho LP, Gao F, Chen Q, Sim LL, Koh TH, Foo D, Ong HY, Tong KL, Tan HC, Yeo TC, Chow KY, Richards AM, Peterson ED, Chua T, Chan MY
Am J Cardiol 2015 Apr 1;115(7):872-8. Epub 2015 Jan 15 doi: 10.1016/j.amjcard.2015.01.010. PMID: 25682439
Outcomes of patients with Killip class III acute myocardial infarction after primary percutaneous coronary intervention.
Tsai TH, Chua S, Hussein H, Leu S, Wu CJ, Hang CL, Fang HY, Chung SY, Fu M, Chen HC, Chang LT, Yeh KH, Yip HK
Crit Care Med 2011 Mar;39(3):436-42. doi: 10.1097/CCM.0b013e318206ccc3. PMID: 21242801

Clinical prediction guides

Clinical features of ST-segment elevation myocardial infarction in young Chinese patients.
Sun Y, Xu J, He Z, Cheng X, Jiang T
Cardiol J 2023;30(4):627-635. Epub 2021 Jul 27 doi: 10.5603/CJ.a2021.0059. PMID: 34312831Free PMC Article
Early Statin Therapy and In-Hospital Outcomes in Acute Coronary Syndrome Patients Presenting with Advanced Killip Class at Admission: Findings from the CCC-ACS Project.
Song X, Zhou X, Li Z, Sun H, Liu H, A G, Hao Y, Liu J, Liu J, Zhao D, Yang Q, Li Y; CCC-ACS Investigators
Am J Cardiovasc Drugs 2022 Nov;22(6):685-694. Epub 2022 Aug 13 doi: 10.1007/s40256-022-00546-5. PMID: 35962306
Clinical predictors and prognostic role of high Killip class in patients with a first episode of anterior ST-segment elevation acute myocardial infarction.
Del Buono MG, Montone RA, Rinaldi R, Gurgoglione FL, Meucci MC, Camilli M, Iannaccone G, Sanna T, Pedicino D, Trani C, Niccoli G, Crea F
J Cardiovasc Med (Hagerstown) 2021 Jul 1;22(7):530-538. doi: 10.2459/JCM.0000000000001168. PMID: 34076600
Outcomes of Nonagenarians With ST Elevation Myocardial Infarction.
Cepas-Guillén PL, Borrego-Rodriguez J, Flores-Umanzor E, Echarte-Morales J, Fernandez-Valledor A, Menendez-Suarez P, Vazquez S, Alonso N, Ortiz JT, Regueiro A, Iglesias I, Andrea R, Masotti M, Perez de Prado A, Brugaletta S, Bayón-Fernandez J, Freixa X, Fernandez-Vazquez F, Sabaté M
Am J Cardiol 2020 Jan 1;125(1):11-18. Epub 2019 Oct 11 doi: 10.1016/j.amjcard.2019.09.046. PMID: 31732135
Outcomes of patients with Killip class III acute myocardial infarction after primary percutaneous coronary intervention.
Tsai TH, Chua S, Hussein H, Leu S, Wu CJ, Hang CL, Fang HY, Chung SY, Fu M, Chen HC, Chang LT, Yeh KH, Yip HK
Crit Care Med 2011 Mar;39(3):436-42. doi: 10.1097/CCM.0b013e318206ccc3. PMID: 21242801

Recent systematic reviews

Mineralocorticoid receptor antagonists in patients with acute myocardial infarction - A systematic review and meta-analysis of randomized trials.
Bossard M, Binbraik Y, Beygui F, Pitt B, Zannad F, Montalescot G, Jolly SS
Am Heart J 2018 Jan;195:60-69. Epub 2017 Sep 15 doi: 10.1016/j.ahj.2017.09.010. PMID: 29224647
Do beta-blockers reduce short-term mortality following acute myocardial infarction? A systematic review and meta-analysis.
Al-Reesi A, Al-Zadjali N, Perry J, Fergusson D, Al-Shamsi M, Al-Thagafi M, Stiell I
CJEM 2008 May;10(3):215-23. doi: 10.1017/s1481803500010137. PMID: 19019272

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