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Diffuse Large B-Cell Lymphoma Associated with Chronic Inflammation

MedGen UID:
397630
•Concept ID:
C2699776
•
Neoplastic Process
Synonyms: Diffuse large B-cell lymphoma associated with chronic inflammation; DLBCL (diffuse large B-cell lymphoma) associated with chronic inflammation
SNOMED CT: DLBCL (diffuse large B-cell lymphoma) associated with chronic inflammation (734076008); Diffuse large B-cell lymphoma associated with chronic inflammation (734076008)

Definition

A diffuse large B-cell lymphoma arising in body cavities or narrow spaces of long standing chronic inflammation. The classic example is the pyothorax-associated lymphoma that arises in the pleural cavity of patients with a history of long standing pyothorax. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiffuse Large B-Cell Lymphoma Associated with Chronic Inflammation

Professional guidelines

PubMed

EBV-positive diffuse large B-cell lymphoma, not otherwise specified: 2022 update on diagnosis, risk-stratification, and management.
Malpica L, Marques-Piubelli ML, Beltran BE, Chavez JC, Miranda RN, Castillo JJ
Am J Hematol 2022 Jul;97(7):951-965. Epub 2022 May 3 doi: 10.1002/ajh.26579. PMID: 35472248
EBV-positive diffuse large B-cell lymphoma, not otherwise specified: 2020 update on diagnosis, risk-stratification and management.
Beltran BE, Castro D, Paredes S, Miranda RN, Castillo JJ
Am J Hematol 2020 Apr;95(4):435-445. Epub 2020 Feb 29 doi: 10.1002/ajh.25760. PMID: 32072672
EBV-positive diffuse large B-cell lymphoma, not otherwise specified: 2018 update on diagnosis, risk-stratification and management.
Castillo JJ, Beltran BE, Miranda RN, Young KH, Chavez JC, Sotomayor EM
Am J Hematol 2018 Jul;93(7):953-962. doi: 10.1002/ajh.25112. PMID: 29984868

Recent clinical studies

Diagnosis

Fibrin-Associated, EBV-Negative Diffuse Large B-Cell Lymphoma Arising in Atrial Myxoma: Expanding the Spectrum of the Entity.
Baugh L, Brown N, Song JY, Pandya S, Montoya V, Perry AM
Int J Surg Pathol 2022 Feb;30(1):39-45. Epub 2021 Apr 29 doi: 10.1177/10668969211014959. PMID: 33913371
Lymphomas arising in immune-privileged sites: insights into biology, diagnosis, and pathogenesis.
King RL, Goodlad JR, Calaminici M, Dotlic S, Montes-Moreno S, Oschlies I, Ponzoni M, Traverse-Glehen A, Ott G, Ferry JA
Virchows Arch 2020 May;476(5):647-665. Epub 2019 Dec 20 doi: 10.1007/s00428-019-02698-3. PMID: 31863183

Therapy

Lymphomas arising in immune-privileged sites: insights into biology, diagnosis, and pathogenesis.
King RL, Goodlad JR, Calaminici M, Dotlic S, Montes-Moreno S, Oschlies I, Ponzoni M, Traverse-Glehen A, Ott G, Ferry JA
Virchows Arch 2020 May;476(5):647-665. Epub 2019 Dec 20 doi: 10.1007/s00428-019-02698-3. PMID: 31863183

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