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Sinus node disease and myopia

MedGen UID:
401121
Concept ID:
C1866960
Disease or Syndrome
Synonyms: SICK SINUS SYNDROME AND MYOPIA; SSS-MYOPIA SYNDROME
 
Monarch Initiative: MONDO:0008423
OMIM®: 182190

Clinical features

From HPO
Sick sinus syndrome
MedGen UID:
20749
Concept ID:
C0037052
Disease or Syndrome
An abnormality involving the generation of the action potential by the sinus node and is characterized by an atrial rate inappropriate for physiological requirements. Manifestations include severe sinus bradycardia, sinus pauses or arrest, sinus node exit block, chronic atrial tachyarrhythmias, alternating periods of atrial bradyarrhythmias and tachyarrhythmias, and inappropriate responses of heart rate during exercise or stress.
Abnormal electrophysiology of sinoatrial node origin
MedGen UID:
868812
Concept ID:
C4023222
Anatomical Abnormality
An abnormality of the sinoatrial (SA) node in the right atrium. THe SA node acts as the pacemaker of the heart.
High myopia
MedGen UID:
78759
Concept ID:
C0271183
Disease or Syndrome
A severe form of myopia with greater than -6.00 diopters.

Recent clinical studies

Clinical prediction guides

Onat A
Hum Genet 1986 Feb;72(2):182-4. doi: 10.1007/BF00283944. PMID: 3943873

Supplemental Content

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