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Grade 1 Follicular Lymphoma

MedGen UID:
408261
•Concept ID:
C1956130
•
Neoplastic Process
Synonyms: Follicular Lymphoma, Grade 1; Lymphoma, Follicular, Grade 1
SNOMED CT: Follicular lymphoma, grade 1 (46744002)

Definition

A follicular lymphoma which contains up to 5 centroblasts per 40X high-power microscopic field. [from NCI]

Professional guidelines

PubMed

Urinary albumin excretion is a predictor of response to treatment and disease progression in low-grade non-Hodgkin's lymphoma.
Pedersen LM, Sørensen PG
Leuk Lymphoma 2004 Mar;45(3):547-51. doi: 10.1080/10428190310001593049. PMID: 15160917

Recent clinical studies

Etiology

Higher World Health Organization grades of follicular lymphoma correlate with better outcome in two Nordic Lymphoma Group trials of rituximab without chemotherapy.
Wahlin BE, Sundström C, Sander B, Christensson B, Jeppsson-Ahlberg Å, Hjalmarsson E, Holte H, Østenstad B, Brown PD, Smeland EB, Kimby E
Leuk Lymphoma 2014 Feb;55(2):288-95. Epub 2013 Jun 14 doi: 10.3109/10428194.2013.802778. PMID: 23662992
Hematologic malignancies with primary retroperitoneal presentation: clinicopathologic study of 32 cases.
Chen L, Kuriakose P, Hawley RC, Janakiraman N, Maeda K
Arch Pathol Lab Med 2005 May;129(5):655-60. doi: 10.5858/2005-129-0655-HMWPRP. PMID: 15859638

Diagnosis

Histiocytic sarcoma transdifferentiated from follicular lymphoma presenting as a cutaneous tumor.
Zeng W, Meck J, Cheson BD, Ozdemirli M
J Cutan Pathol 2011 Dec;38(12):999-1003. Epub 2011 Aug 23 doi: 10.1111/j.1600-0560.2011.01769.x. PMID: 21883369
Low-grade follicular lymphoma in the dura: rare mimic of meningioma.
Low I, Allen J
Neuropathology 2006 Dec;26(6):564-8. doi: 10.1111/j.1440-1789.2006.00730.x. PMID: 17203594
Hematologic malignancies with primary retroperitoneal presentation: clinicopathologic study of 32 cases.
Chen L, Kuriakose P, Hawley RC, Janakiraman N, Maeda K
Arch Pathol Lab Med 2005 May;129(5):655-60. doi: 10.5858/2005-129-0655-HMWPRP. PMID: 15859638
Low-grade follicular lymphoma of the small intestine.
Poggi MM, Cong PJ, Coleman CN, Jaffe ES
J Clin Gastroenterol 2002 Feb;34(2):155-9. doi: 10.1097/00004836-200202000-00011. PMID: 11782611

Therapy

Higher World Health Organization grades of follicular lymphoma correlate with better outcome in two Nordic Lymphoma Group trials of rituximab without chemotherapy.
Wahlin BE, Sundström C, Sander B, Christensson B, Jeppsson-Ahlberg Å, Hjalmarsson E, Holte H, Østenstad B, Brown PD, Smeland EB, Kimby E
Leuk Lymphoma 2014 Feb;55(2):288-95. Epub 2013 Jun 14 doi: 10.3109/10428194.2013.802778. PMID: 23662992
Hematologic malignancies with primary retroperitoneal presentation: clinicopathologic study of 32 cases.
Chen L, Kuriakose P, Hawley RC, Janakiraman N, Maeda K
Arch Pathol Lab Med 2005 May;129(5):655-60. doi: 10.5858/2005-129-0655-HMWPRP. PMID: 15859638

Prognosis

Higher World Health Organization grades of follicular lymphoma correlate with better outcome in two Nordic Lymphoma Group trials of rituximab without chemotherapy.
Wahlin BE, Sundström C, Sander B, Christensson B, Jeppsson-Ahlberg Å, Hjalmarsson E, Holte H, Østenstad B, Brown PD, Smeland EB, Kimby E
Leuk Lymphoma 2014 Feb;55(2):288-95. Epub 2013 Jun 14 doi: 10.3109/10428194.2013.802778. PMID: 23662992
Histiocytic sarcoma transdifferentiated from follicular lymphoma presenting as a cutaneous tumor.
Zeng W, Meck J, Cheson BD, Ozdemirli M
J Cutan Pathol 2011 Dec;38(12):999-1003. Epub 2011 Aug 23 doi: 10.1111/j.1600-0560.2011.01769.x. PMID: 21883369
Different histopathological types of orbital lymphoma 16 years after systemic follicular lymphoma: immunohistochemical and immunogenetic analyses of two cases.
Matsuo T, Ichimura K, Shinagawa K, Yoshino T
J Clin Exp Hematop 2008 Apr;48(1):17-24. doi: 10.3960/jslrt.48.17. PMID: 18434689

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