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Retroperitoneal leiomyosarcoma

MedGen UID:
412162
•Concept ID:
C2187547
•
Neoplastic Process
Synonyms: leiomyosarcoma of retroperitoneal space; Retroperitoneal Leiomyosarcoma; retroperitoneal leiomyosarcoma; retroperitoneal space leiomyosarcoma
 
Monarch Initiative: MONDO:0003370

Definition

An aggressive malignant smooth muscle neoplasm, arising from the retroperitoneum. It is characterized by a proliferation of neoplastic spindle cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRetroperitoneal leiomyosarcoma

Professional guidelines

PubMed

Serotonin Syndrome Complicating Treatment of Ifosfamide Neurotoxicity With Methylene Blue.
Snyder M, Gangadhara S, Brohl AS, Ludlow S, Nanjappa S
Cancer Control 2017 Oct-Dec;24(5):1073274817729070. doi: 10.1177/1073274817729070. PMID: 28975823Free PMC Article
Laboratory and clinical evidence of synergistic cytotoxicity of sequential treatment with gemcitabine followed by docetaxel in the treatment of sarcoma.
Leu KM, Ostruszka LJ, Shewach D, Zalupski M, Sondak V, Biermann JS, Lee JS, Couwlier C, Palazzolo K, Baker LH
J Clin Oncol 2004 May 1;22(9):1706-12. doi: 10.1200/JCO.2004.08.043. PMID: 15117993

Recent clinical studies

Etiology

A CT-based radiomics classification model for the prediction of histological type and tumour grade in retroperitoneal sarcoma (RADSARC-R): a retrospective multicohort analysis.
Arthur A, Orton MR, Emsley R, Vit S, Kelly-Morland C, Strauss D, Lunn J, Doran S, Lmalem H, Nzokirantevye A, Litiere S, Bonvalot S, Haas R, Gronchi A, Van Gestel D, Ducassou A, Raut CP, Meeus P, Spalek M, Hatton M, Le Pechoux C, Thway K, Fisher C, Jones R, Huang PH, Messiou C
Lancet Oncol 2023 Nov;24(11):1277-1286. doi: 10.1016/S1470-2045(23)00462-X. PMID: 37922931Free PMC Article
Potential application value of PET/computed tomography in retroperitoneal leiomyosarcoma and a literature review.
Gao YJ, Yang Z, Yu JY, Li N, Wang XJ, Zhou NN
Nucl Med Commun 2021 Jul 1;42(7):800-810. doi: 10.1097/MNM.0000000000001388. PMID: 33741860
CT imaging improves histopathological grading of retroperitoneal leiomyosarcomas.
Mcaddy NC, Hallin M, Strauss D, Smith M, Hayes A, Yusuf S, Moskovic E, Fotiadis N, van Houdt W, Jones RL, Gronchi A, Thway K, Messiou C
Eur J Surg Oncol 2020 Feb;46(2):288-292. Epub 2019 Oct 10 doi: 10.1016/j.ejso.2019.10.007. PMID: 31653457
Surgical resection for recurrent retroperitoneal leiomyosarcoma and liposarcoma.
Nathenson MJ, Barysauskas CM, Nathenson RA, Regine WF, Hanna N, Sausville E
World J Surg Oncol 2018 Oct 11;16(1):203. doi: 10.1186/s12957-018-1505-4. PMID: 30309356Free PMC Article
Retroperitoneal leiomyosarcoma: a review of the literature.
Fisher NW, Nutinsky CL
J Am Osteopath Assoc 1989 Aug;89(8):1058-60, 1065. PMID: 2670858

Diagnosis

Perivascular epithelioid cell tumour-mimicking retroperitoneal leiomyosarcoma.
Siddiqi S, Mesropyan L
BMJ Case Rep 2022 Aug 19;15(8) doi: 10.1136/bcr-2022-250252. PMID: 35985749Free PMC Article
Retroperitoneal Leiomyosarcoma with Elevated CA 19-9.
Wechsler B, Anton B, Yim D
S D Med 2022 Apr;75(4):154-157. PMID: 35709345
Surgical resection for recurrent retroperitoneal leiomyosarcoma and liposarcoma.
Nathenson MJ, Barysauskas CM, Nathenson RA, Regine WF, Hanna N, Sausville E
World J Surg Oncol 2018 Oct 11;16(1):203. doi: 10.1186/s12957-018-1505-4. PMID: 30309356Free PMC Article
Comparison between retroperitoneal leiomyosarcoma and dedifferentiated liposarcoma.
Ishii T, Kohashi K, Ootsuka H, Iura K, Maekawa A, Yamada Y, Bekki H, Yoshimoto M, Yamamoto H, Iwamoto Y, Oda Y
Pathol Res Pract 2017 Jun;213(6):634-638. Epub 2017 May 1 doi: 10.1016/j.prp.2017.04.022. PMID: 28552535
Retroperitoneal leiomyosarcoma.
De Waele B, Van Belle S, Claes H, Goovaerts G, Delvaux G, Willems G
Acta Chir Belg 1987 Jul-Aug;87(4):229-34. PMID: 3661002

Therapy

Nomogram predicting overall survival after surgical resection for retroperitoneal leiomyosarcoma patients.
Zhuang A, Yue X, Tong H, Zhang Y, He F, Lu W
Front Endocrinol (Lausanne) 2023;14:1160817. Epub 2023 Jul 17 doi: 10.3389/fendo.2023.1160817. PMID: 37534215Free PMC Article
Web-based nomograms for predicting overall survival and cancer-specific survival in retroperitoneal leiomyosarcoma: a population-based analysis.
Feng Z, Li Y
J Cancer Res Clin Oncol 2023 Oct;149(13):11735-11748. Epub 2023 Jul 5 doi: 10.1007/s00432-023-05052-y. PMID: 37405479
A novel nomogram model to predict the overall survival of patients with retroperitoneal leiomyosarcoma: a large cohort retrospective study.
Huang C, Yu QP, Li H, Ding Z, Zhou Z, Shi X
Sci Rep 2022 Jul 13;12(1):11851. doi: 10.1038/s41598-022-16055-z. PMID: 35831450Free PMC Article
(125)I brachytherapy seeds implantation for an inoperable large retroperitoneal leiomyosarcoma.
Di X, Liang Y, Yu H, Zhao J, Wang Z, Zhao J, Sui A, Zhang H, Wang J
J Cancer Res Ther 2020;16(2):397-400. doi: 10.4103/jcrt.JCRT_66_18. PMID: 32474530
Outcome of iliocaval resection and reconstruction for retroperitoneal sarcoma.
Ferraris M, Callegaro D, Barretta F, Fiore M, Radaelli S, Stacchiotti S, Miceli R, Socrate AM, Locati P, Gronchi A
J Vasc Surg Venous Lymphat Disord 2019 Jul;7(4):547-556. Epub 2019 Feb 18 doi: 10.1016/j.jvsv.2018.10.023. PMID: 30792153

Prognosis

A CT-based radiomics classification model for the prediction of histological type and tumour grade in retroperitoneal sarcoma (RADSARC-R): a retrospective multicohort analysis.
Arthur A, Orton MR, Emsley R, Vit S, Kelly-Morland C, Strauss D, Lunn J, Doran S, Lmalem H, Nzokirantevye A, Litiere S, Bonvalot S, Haas R, Gronchi A, Van Gestel D, Ducassou A, Raut CP, Meeus P, Spalek M, Hatton M, Le Pechoux C, Thway K, Fisher C, Jones R, Huang PH, Messiou C
Lancet Oncol 2023 Nov;24(11):1277-1286. doi: 10.1016/S1470-2045(23)00462-X. PMID: 37922931Free PMC Article
Surgical resection for recurrent retroperitoneal leiomyosarcoma and liposarcoma.
Nathenson MJ, Barysauskas CM, Nathenson RA, Regine WF, Hanna N, Sausville E
World J Surg Oncol 2018 Oct 11;16(1):203. doi: 10.1186/s12957-018-1505-4. PMID: 30309356Free PMC Article
Comparison between retroperitoneal leiomyosarcoma and dedifferentiated liposarcoma.
Ishii T, Kohashi K, Ootsuka H, Iura K, Maekawa A, Yamada Y, Bekki H, Yoshimoto M, Yamamoto H, Iwamoto Y, Oda Y
Pathol Res Pract 2017 Jun;213(6):634-638. Epub 2017 May 1 doi: 10.1016/j.prp.2017.04.022. PMID: 28552535
Retroperitoneal leiomyosarcoma: a review of the literature.
Fisher NW, Nutinsky CL
J Am Osteopath Assoc 1989 Aug;89(8):1058-60, 1065. PMID: 2670858
Retroperitoneal leiomyosarcoma.
De Waele B, Van Belle S, Claes H, Goovaerts G, Delvaux G, Willems G
Acta Chir Belg 1987 Jul-Aug;87(4):229-34. PMID: 3661002

Clinical prediction guides

A CT-based radiomics classification model for the prediction of histological type and tumour grade in retroperitoneal sarcoma (RADSARC-R): a retrospective multicohort analysis.
Arthur A, Orton MR, Emsley R, Vit S, Kelly-Morland C, Strauss D, Lunn J, Doran S, Lmalem H, Nzokirantevye A, Litiere S, Bonvalot S, Haas R, Gronchi A, Van Gestel D, Ducassou A, Raut CP, Meeus P, Spalek M, Hatton M, Le Pechoux C, Thway K, Fisher C, Jones R, Huang PH, Messiou C
Lancet Oncol 2023 Nov;24(11):1277-1286. doi: 10.1016/S1470-2045(23)00462-X. PMID: 37922931Free PMC Article
Nomogram predicting overall survival after surgical resection for retroperitoneal leiomyosarcoma patients.
Zhuang A, Yue X, Tong H, Zhang Y, He F, Lu W
Front Endocrinol (Lausanne) 2023;14:1160817. Epub 2023 Jul 17 doi: 10.3389/fendo.2023.1160817. PMID: 37534215Free PMC Article
Web-based nomograms for predicting overall survival and cancer-specific survival in retroperitoneal leiomyosarcoma: a population-based analysis.
Feng Z, Li Y
J Cancer Res Clin Oncol 2023 Oct;149(13):11735-11748. Epub 2023 Jul 5 doi: 10.1007/s00432-023-05052-y. PMID: 37405479
A novel nomogram model to predict the overall survival of patients with retroperitoneal leiomyosarcoma: a large cohort retrospective study.
Huang C, Yu QP, Li H, Ding Z, Zhou Z, Shi X
Sci Rep 2022 Jul 13;12(1):11851. doi: 10.1038/s41598-022-16055-z. PMID: 35831450Free PMC Article
CT imaging improves histopathological grading of retroperitoneal leiomyosarcomas.
Mcaddy NC, Hallin M, Strauss D, Smith M, Hayes A, Yusuf S, Moskovic E, Fotiadis N, van Houdt W, Jones RL, Gronchi A, Thway K, Messiou C
Eur J Surg Oncol 2020 Feb;46(2):288-292. Epub 2019 Oct 10 doi: 10.1016/j.ejso.2019.10.007. PMID: 31653457

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